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Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements

Nature communications, 2018-04, Vol.9 (1), p.1337-13, Article 1337

2018

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Defining a conformational ensemble that directs activation of PPARγ

Nature communications, 2018-05, Vol.9 (1), p.1794-16, Article 1794

2018

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Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication

Antimicrobial agents and chemotherapy, 2016-04, Vol.60 (4), p.2195-2208

2016

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Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes

Nucleic acids research, 2017-08, Vol.45 (14), p.8596

2017

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Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate

Nature communications, 2014-11, Vol.5 (1), p.5395-5395, Article 5395

2014

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Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1

Structure (London), 2019-01, Vol.27 (1), p.66-77.e5

2019

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Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

The Journal of biological chemistry, 2023-12, Vol.299 (12), p.105475, Article 105475

2023

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Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

ACS chemical biology, 2016-07, Vol.11 (7), p.1795-1799

2016

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Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection

PloS one, 2015-08, Vol.10 (8), p.e0134474-e0134474

2015

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Elucidating a Relationship between Conformational Sampling and Drug Resistance in HIV‑1 Protease

Biochemistry (Easton), 2013-05, Vol.52 (19), p.3278-3288

2013

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Identification of potent small molecule inhibitors of SARS-CoV-2 entry

SLAS discovery, 2022-01, Vol.27 (1), p.8-19

2022

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Enhanced archaeal laccase production in recombinant Escherichia coli by modification of N-terminal propeptide and twin arginine translocation motifs

Journal of industrial microbiology & biotechnology, 2012-10, Vol.39 (10), p.1523-1532

2012

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Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

Journal of medicinal chemistry, 2020-12, Vol.63 (24), p.15639-15654

2020

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Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates

Molecular microbiology, 2012-11, Vol.86 (4), p.971-987

2012

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An alternate binding site for PPARγ ligands

Nature communications, 2014-04, Vol.5 (1), p.3571-3571, Article 3571

2014

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The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids

Cell chemical biology, 2020-10, Vol.27 (10), p.1272-1284.e4

2020

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Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA

Structure (London), 2017-10, Vol.25 (10), p.1506-1518.e4

2017

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Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915

European journal of medicinal chemistry, 2023-10, Vol.258, p.115582, Article 115582

2023

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Correction to Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

Journal of medicinal chemistry, 2021-04, Vol.64 (8), p.5216-5220

2021

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The Tat inhibitor didehydro‐cortistatin A suppresses SIV replication and reactivation

The FASEB journal, 2019-07, Vol.33 (7), p.8280-8293

2019

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Advances in Orphan Nuclear Receptor Pharmacology: A New Era in Drug Discovery

ACS pharmacology & translational science, 2018-11, Vol.1 (2), p.134-137

de Vera, Ian Mitchelle S

2018

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Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin‐like proteins of Archaea

The FEBS journal, 2016-10, Vol.283 (19), p.3567-3586

2016

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Probing the Complex Binding Modes of the PPARγ Partial Agonist 2‑Chloro‑N‑(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy

Journal of medicinal chemistry, 2016-11, Vol.59 (22), p.10335-10341

2016

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Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements

Defining a conformational ensemble that directs activation of PPARγ

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes

Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate

Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1

Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection

Elucidating a Relationship between Conformational Sampling and Drug Resistance in HIV‑1 Protease

Identification of potent small molecule inhibitors of SARS-CoV-2 entry

Enhanced archaeal laccase production in recombinant Escherichia coli by modification of N-terminal propeptide and twin arginine translocation motifs

Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates

An alternate binding site for PPARγ ligands

The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids

Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA

Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915

Correction to Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

The Tat inhibitor didehydro‐cortistatin A suppresses SIV replication and reactivation

Advances in Orphan Nuclear Receptor Pharmacology: A New Era in Drug Discovery

International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023

Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin‐like proteins of Archaea

Probing the Complex Binding Modes of the PPARγ Partial Agonist 2‑Chloro‑N‑(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy

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