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1,3-Diaryl-4,5,6,7-tetrahydro-2H-isoindole Derivatives: A New Series of Potent and Selective COX-2 Inhibitors in Which a Sulfonyl Group Is Not a Structural Requisite

Journal of medicinal chemistry, 2000-11, Vol.43 (24), p.4582-4593

2000

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S35972, a direct‐acting thrombin inhibitor with high oral bioavailability and antithrombotic efficacy

Journal of thrombosis and haemostasis, 2011-07, Vol.9 (7), p.1375-1382

2011

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Psychotropic Profile of S 17092, a Prolyl Endopeptidase Inhibitor, Using Quantitative EEG in Young Healthy Volunteers

Neuropsychobiology, 2007-01, Vol.55 (3-4), p.176-183

2007

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P.2.d.004 S41744, a dual NK1 antagonist/5-HT reuptake inhibitor and antidepressant: a comparison to aprepitant and paroxetine

European neuropsychopharmacology, 2009, Vol.19, p.S432-S432

2009

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Pharmacodynamic and pharmacokinetic profile of S 17092, a new orally active prolyl endopeptidase inhibitor, in elderly healthy volunteers. A phase I study

British journal of clinical pharmacology, 2000-10, Vol.50 (4), p.350-359

2000

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S 18326: a thrombin inhibitor that shows potential for oral treatment of thromboembolic disorders

Expert opinion on investigational drugs, 1999-02, Vol.8 (2), p.173-180

1999

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Pharmacological profile of a novel series of NK1 antagonists. In vitro and in vivo potency of benzimidazolone derivatives

European journal of medicinal chemistry, 1997-11, Vol.32 (11), p.843-868

1997

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Selection of S18326 as a new potent and selective boronic acid direct thrombin inhibitor

Thrombosis and haemostasis, 1997-10, Vol.78 (4), p.1221-1227

1997

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Biguanide derivatives: agonist pharmacology at 5-hydroxytryptamine type 3 receptors in vitro

Molecular pharmacology, 1994-10, Vol.46 (4), p.732-742

1994

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Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury

FEBS letters, 1997-01, Vol.402 (2), p.111-115

1997

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Selective blockade of neurokinin (NK)(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats

Journal of neurochemistry, 2001-03, Vol.76 (6), p.1949-1954

2001

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Effects of Ceramide on Apoptosis, Proteoglycan Degradation, and Matrix Metalloproteinase Expression in Rabbit Articular Cartilage

Biochemical and biophysical research communications, 2000-01, Vol.267 (1), p.438-444

2000

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Invertebres marins du lagon neo-caledonien-V : Isolement et identification des metabolites d'une nouvelle espece de spongiaire, pseudaxinyssa cantharella

Tetrahedron, 1985, Vol.41 (24), p.6019-6033

1985

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New fibrinolytic agents: benzothiophene derivatives as inhibitors of the t-PA–PAI-1 complex formation

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1705-1708

2003

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ID: 171 S-35225 decreases plasma PAI-1 activity both in vitro and in vivo

Journal of thrombosis and haemostasis, 2006-10, Vol.4 (s1), p.166-166

2006

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S 17092-1, a Highly Potent, Specific and Cell Permeant Inhibitor of Human Proline Endopeptidase

Biochemical and biophysical research communications, 1999-04, Vol.257 (3), p.657-661

1999

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An expeditious multigram preparation of the marine protein kinase inhibitor debromohymenialdisine

Tetrahedron letters, 2003-12, Vol.44 (52), p.9263-9265

2003

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Further evidence for a dissociation between different forms of mnemonic expressions in a mouse model of age-related cognitive decline: effects of tacrine and S 17092, a novel prolyl endopeptidase inhibitor

Learning & memory (Cold Spring Harbor, N.Y.), 2000-05, Vol.7 (3), p.159-169

2000

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Effects of Ceramide on Aggrecanase Activity in Rabbit Articular Cartilage

Biochemical and biophysical research communications, 2001-05, Vol.283 (5), p.1105-1110

2001

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Anti-thrombotic and anticoagulant effects of S35898 an orally active thrombin inhibitor

Journal of thrombosis and haemostasis, 2003-07, Vol.1, p.P2042-P2042

2003

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Synthesis of benzyl (6 S)-1,3-dichloro-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2- a]pyrazine-6-carboxylic ester, a new conformationally constrained peptidomimetic derivative

Tetrahedron letters, 2002-05, Vol.43 (19), p.3499-3501

2002

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Invertebres marins du lagon neo-caledonien—VI : Isolement et identification de onze sterols de type hydroxymethyl-3β nor-a cholestane du spongiaire, pseudaxinyssa cantharella

Tetrahedron, 1985, Vol.41 (24), p.6035-6039

1985

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Selective blockade of neurokinin (NK) sub(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats

Journal of neurochemistry, 2001-03, Vol.76 (6), p.1949-1954

2001

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Invertebres marins du lagon neo-caledonien—VI

Tetrahedron, 1985-01, Vol.41 (24), p.6035-6039

1985

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Phosphoramidon Inhibits the Conversion of Big ET-1 into ET-1 in the Pithed Rat and in Isolated Perfused Rat Kidneys

Journal of cardiovascular pharmacology, 1993, Vol.22 Suppl 8 (Supplement 8), p.S81-S84

1993

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1,3-Diaryl-4,5,6,7-tetrahydro-2H-isoindole Derivatives: A New Series of Potent and Selective COX-2 Inhibitors in Which a Sulfonyl Group Is Not a Structural Requisite

S35972, a direct‐acting thrombin inhibitor with high oral bioavailability and antithrombotic efficacy

Psychotropic Profile of S 17092, a Prolyl Endopeptidase Inhibitor, Using Quantitative EEG in Young Healthy Volunteers

P.2.d.004 S41744, a dual NK1 antagonist/5-HT reuptake inhibitor and antidepressant: a comparison to aprepitant and paroxetine

Pharmacodynamic and pharmacokinetic profile of S 17092, a new orally active prolyl endopeptidase inhibitor, in elderly healthy volunteers. A phase I study

S 18326: a thrombin inhibitor that shows potential for oral treatment of thromboembolic disorders

Pharmacological profile of a novel series of NK1 antagonists. In vitro and in vivo potency of benzimidazolone derivatives

Selection of S18326 as a new potent and selective boronic acid direct thrombin inhibitor

Biguanide derivatives: agonist pharmacology at 5-hydroxytryptamine type 3 receptors in vitro

Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury

Selective blockade of neurokinin (NK)(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats

Effects of Ceramide on Apoptosis, Proteoglycan Degradation, and Matrix Metalloproteinase Expression in Rabbit Articular Cartilage

Invertebres marins du lagon neo-caledonien-V : Isolement et identification des metabolites d'une nouvelle espece de spongiaire, pseudaxinyssa cantharella

New fibrinolytic agents: benzothiophene derivatives as inhibitors of the t-PA–PAI-1 complex formation

ID: 171 S-35225 decreases plasma PAI-1 activity both in vitro and in vivo

S 17092-1, a Highly Potent, Specific and Cell Permeant Inhibitor of Human Proline Endopeptidase

An expeditious multigram preparation of the marine protein kinase inhibitor debromohymenialdisine

Further evidence for a dissociation between different forms of mnemonic expressions in a mouse model of age-related cognitive decline: effects of tacrine and S 17092, a novel prolyl endopeptidase inhibitor

Effects of Ceramide on Aggrecanase Activity in Rabbit Articular Cartilage

Anti-thrombotic and anticoagulant effects of S35898 an orally active thrombin inhibitor

Synthesis of benzyl (6 S)-1,3-dichloro-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2- a]pyrazine-6-carboxylic ester, a new conformationally constrained peptidomimetic derivative

Invertebres marins du lagon neo-caledonien—VI : Isolement et identification de onze sterols de type hydroxymethyl-3β nor-a cholestane du spongiaire, pseudaxinyssa cantharella

Selective blockade of neurokinin (NK) sub(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats

Invertebres marins du lagon neo-caledonien—VI

Phosphoramidon Inhibits the Conversion of Big ET-1 into ET-1 in the Pithed Rat and in Isolated Perfused Rat Kidneys

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