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Optimizing Divalent Inhibitors of Pseudomonas aeruginosa Lectin LecA by Using A Rigid Spacer

Chemistry : a European journal, 2013-12, Vol.19 (50), p.16923-16927

2013

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Functionalization of a Rigid Divalent Ligand for LecA, a Bacterial Adhesion Lectin

ChemistryOpen (Weinheim), 2015-08, Vol.4 (4), p.463-470

2015

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ITAM-derived phosphopeptide-containing dendrimers as multivalent ligands for Syk tandem SH2 domain

Organic & biomolecular chemistry, 2009, Vol.7 (19), p.4088

2009

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Site-specific peptide and protein immobilization on surface plasmon resonance chips via strain-promoted cycloaddition

Lab on a chip, 2013-01, Vol.13 (10), p.1863-1867

2013

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Synthesis of Lactose Dendrimers and Multivalency Effects in Binding to the Cholera Toxin B Subunit

European journal of organic chemistry, 2001-12, Vol.2001 (24), p.4685-4692

2001

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Thiourea-based spacers in potent divalent inhibitors of Pseudomonas aeruginosa virulence lectin LecA

Organic & biomolecular chemistry, 2015-11, Vol.13 (44), p.10923-10928

2015

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Peptidomimetic Ligands for the Tandem SH2 Domain of the Syk Protein Involved in Signal Transduction

Advances in experimental medicine and biology, 2009, Vol.611, p.81-82

2009

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Handbook of surface plasmon resonance

1, 2008

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Unusual binding of Grb2 protein to a bivalent polyproline-ligand immobilized on a SPR sensor: Intermolecular bivalent binding

Biochimica et biophysica acta, 2013-02, Vol.1834 (2), p.524-535

2013

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Surface plasmon resonance: a general introduction

Methods in molecular biology (Clifton, N.J.), 2010-01, Vol.627, p.1

2010

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Affinity constants for small molecules from SPR competition experiments

Methods in molecular biology (Clifton, N.J.), 2010-01, Vol.627, p.101

de Mol, Nico J

2010

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ITAM-derived phosphopeptide-containing dendrimers as multivalent ligands for Syk tandem SH2 domain

Organic & biomolecular chemistry, 2009-10, Vol.7 (19), p.4088-4094

2009

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Cell permeable ITAM constructs for the modulation of mediator release in mast cells

Organic & biomolecular chemistry, 2011-02, Vol.9 (3), p.82-833

2011

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Tissue-type plasminogen activator binds to Aβ and AIAPP amyloid fibrils with multiple domains

Amyloid, 2013-06, Vol.20 (2), p.113-121

2013

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Switching between low and high affinity for the Syk tandem SH2 domain by irradiation of azobenzene containing ITAM peptidomimetics

Journal of peptide science, 2009-10, Vol.15 (10), p.685-691

2009

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Surface plasmon resonance for proteomics

Methods in molecular biology (Clifton, N.J.), 2012, Vol.800, p.33

de Mol, Nico J

2012

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Protein Flexibility and Ligand Rigidity: A Thermodynamic and Kinetic Study of ITAM-Based Ligand Binding to Syk Tandem SH2

Chembiochem : a European journal of chemical biology, 2005-12, Vol.6 (12), p.2261-2270

2005

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Cyclic phosphopeptides for interference with Grb2 SH2 domain signal transduction prepared by ring-closing metathesis and phosphorylation

Organic & biomolecular chemistry, 2003-10, Vol.1 (19), p.3297-3303

2003

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Surface Plasmon Resonance Thermodynamic and Kinetic Analysis as a Strategic Tool in Drug Design. Distinct Ways for Phosphopeptides to Plug into Src- and Grb2 SH2 Domains

Journal of medicinal chemistry, 2005-02, Vol.48 (3), p.753-763

2005

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Changes in structural dynamics of the Grb2 adaptor protein upon binding of phosphotyrosine ligand to its SH2 domain

Biochimica et biophysica acta, 2004-07, Vol.1700 (1), p.53-64

2004

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Effects of oxatomide and derivatives on high affinity IgE receptor-activated signal transduction pathways in rat basophilic leukemia cells: role of protein tyrosine hyperphosphorylation and inhibition of extracellular calcium influx

Biochemical pharmacology, 1998-09, Vol.56 (6), p.693-701

1998

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A photoswitchable ITAM peptidomimetic: Synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis– trans isomerization on binding

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (3), p.1393-1399

2008

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Replacement of the Intervening Amino Acid Sequence of a Syk-Binding Diphosphopeptide by a Nonpeptide Spacer with Preservation of High Affinity

Chembiochem : a European journal of chemical biology, 2002-03, Vol.3 (2-3), p.238-242

2002

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Amino propynyl benzoic acid building block in rigid spacers of divalent ligands binding to the syk SH2 domains with equally high affinity as the natural ligand

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (7), p.1241-1244

2003

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Role of solution conformation and flexibility of short peptide ligands that bind to the p56(lck) SH2 domain

Bioorganic & medicinal chemistry, 2003-03, Vol.11 (6), p.941-949

2003

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Optimizing Divalent Inhibitors of Pseudomonas aeruginosa Lectin LecA by Using A Rigid Spacer

Functionalization of a Rigid Divalent Ligand for LecA, a Bacterial Adhesion Lectin

ITAM-derived phosphopeptide-containing dendrimers as multivalent ligands for Syk tandem SH2 domain

Site-specific peptide and protein immobilization on surface plasmon resonance chips via strain-promoted cycloaddition

Synthesis of Lactose Dendrimers and Multivalency Effects in Binding to the Cholera Toxin B Subunit

Thiourea-based spacers in potent divalent inhibitors of Pseudomonas aeruginosa virulence lectin LecA

Peptidomimetic Ligands for the Tandem SH2 Domain of the Syk Protein Involved in Signal Transduction

Handbook of surface plasmon resonance

Unusual binding of Grb2 protein to a bivalent polyproline-ligand immobilized on a SPR sensor: Intermolecular bivalent binding

Surface plasmon resonance: a general introduction

Affinity constants for small molecules from SPR competition experiments

ITAM-derived phosphopeptide-containing dendrimers as multivalent ligands for Syk tandem SH2 domain

Cell permeable ITAM constructs for the modulation of mediator release in mast cells

Tissue-type plasminogen activator binds to Aβ and AIAPP amyloid fibrils with multiple domains

Switching between low and high affinity for the Syk tandem SH2 domain by irradiation of azobenzene containing ITAM peptidomimetics

Surface plasmon resonance for proteomics

Protein Flexibility and Ligand Rigidity: A Thermodynamic and Kinetic Study of ITAM-Based Ligand Binding to Syk Tandem SH2

Cyclic phosphopeptides for interference with Grb2 SH2 domain signal transduction prepared by ring-closing metathesis and phosphorylation

Surface Plasmon Resonance Thermodynamic and Kinetic Analysis as a Strategic Tool in Drug Design. Distinct Ways for Phosphopeptides to Plug into Src- and Grb2 SH2 Domains

Changes in structural dynamics of the Grb2 adaptor protein upon binding of phosphotyrosine ligand to its SH2 domain

Effects of oxatomide and derivatives on high affinity IgE receptor-activated signal transduction pathways in rat basophilic leukemia cells: role of protein tyrosine hyperphosphorylation and inhibition of extracellular calcium influx

A photoswitchable ITAM peptidomimetic: Synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis– trans isomerization on binding

Replacement of the Intervening Amino Acid Sequence of a Syk-Binding Diphosphopeptide by a Nonpeptide Spacer with Preservation of High Affinity

Amino propynyl benzoic acid building block in rigid spacers of divalent ligands binding to the syk SH2 domains with equally high affinity as the natural ligand

Role of solution conformation and flexibility of short peptide ligands that bind to the p56(lck) SH2 domain

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