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Characterization of a Novel, Non-peptidyl Antagonist of the Human Glucagon Receptor

The Journal of biological chemistry, 1999-03, Vol.274 (13), p.8694-8697

1999

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The discovery of sulfonylated dipeptides as Potent VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2709-2713

2001

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N-(3-Phenylsulfonyl-3-piperidinoyl)-phenylalanine derivatives as potent, selective VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (5), p.885-890

2003

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Identification of Unique VLA-4 Antagonists from a Combinatorial Library

Bioorganic & medicinal chemistry letters, 2002-02, Vol.12 (4), p.685-688

2002

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N-(Arylacetyl)-biphenylalanines as Potent VLA-4 Antagonists

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (16), p.2141-2144

2002

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N-Tetrahydrofuroyl-( l)-phenylalanine derivatives as potent VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (11), p.1497-1500

2002

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A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor

Journal of medicinal chemistry, 1993-10, Vol.36 (21), p.3207-3210

1993

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N-Aryl-prolyl-dipeptides as potent antagonists of VLA-4

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (16), p.2205-2208

2002

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Potent, orally absorbed glucagon receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-03, Vol.9 (5), p.641-646

1999

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Total synthesis of (.+-.)-dysidin, a marine metabolite containing an N-acyl-O-methyltetramic acid

Journal of organic chemistry, 1984-09, Vol.49 (19), p.3489-3493

1984

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Pyrroles and other heterocycles as inhibitors of P38 kinase

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (19), p.2689-2694

1998

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Total synthesis of halogenated monoterpene marine natural products via the Diels-Alder reaction

Journal of organic chemistry, 1985-10, Vol.50 (20), p.3738-3749

1985

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Deprotection of N- tert-butoxycarbonyl (Boc) groups in the presence of tert-butyl esters

Tetrahedron letters, 2000-09, Vol.41 (36), p.7013-7016

2000

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The synthesis of (2S,4S,5S) -5-(N-BOC)-amino-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid lactone, an hydroxyethylene dipeptide isostere precusor

Tetrahedron letters, 1989, Vol.30 (4), p.415-418

1989

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Molecular Basis for p38 Protein Kinase Inhibitor Specificity

Biochemistry (Easton), 1998-11, Vol.37 (47), p.16573-16581

1998

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Carbohydroxamido-oxazolidines: antibacterial agents that target lipid A biosynthesis

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (3), p.313-318

1999

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Total synthesis of (+)-demethyldysidenin and (-)-demethylisodysidenin, hexachlorinated amino acids from the marine sponge Dysidea herbacea. Assignment of absolute stereochemistry

Journal of the American Chemical Society, 1985-01, Vol.107 (1), p.199-203

1985

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Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow

The Journal of pharmacology and experimental therapeutics, 2002-07, Vol.302 (1), p.153

2002

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A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence

The Journal of pharmacology and experimental therapeutics, 2003-09, Vol.306 (3), p.903

2003

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The Discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2002-02, Vol.12 (4), p.611-614

2002

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CorrigendumCorrigendum to “The discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists”[Bioorg. Med. Chem. Lett. 12 (2002) 611]

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (12), p.1695-1695

2002

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Synthesis of costatolide, a halogenated monoterpenoid from the red alga Plocamium costatum

Journal of organic chemistry, 1983-04, Vol.48 (7), p.1123-1125

1983

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The design, binding affinity prediction and synthesis of macrocyclic angiotensin II AT1 and AT2 receptor antagonists

Bioorganic & medicinal chemistry letters, 1996-04, Vol.6 (8), p.923-928

1996

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Molecular Basis for p38 Protein Kinase Inhibitor Specificity

Biochemistry (Easton), 1999-03, Vol.38 (11), p.3456-3456

1999

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The SAR of 6-(N-alkyl-N-acyl)-2-propyl-3-[(2′-tetrazol-5-yl)biphen-4-yl)methyl]-quinazolinones as balanced affinity antagonists of the human AT1 and AT2 receptors

Bioorganic & medicinal chemistry letters, 1995-07, Vol.5 (13), p.1359-1364

1995

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Characterization of a Novel, Non-peptidyl Antagonist of the Human Glucagon Receptor

The discovery of sulfonylated dipeptides as Potent VLA-4 antagonists

N-(3-Phenylsulfonyl-3-piperidinoyl)-phenylalanine derivatives as potent, selective VLA-4 antagonists

Identification of Unique VLA-4 Antagonists from a Combinatorial Library

N-(Arylacetyl)-biphenylalanines as Potent VLA-4 Antagonists

N-Tetrahydrofuroyl-( l)-phenylalanine derivatives as potent VLA-4 antagonists

A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor

N-Aryl-prolyl-dipeptides as potent antagonists of VLA-4

Potent, orally absorbed glucagon receptor antagonists

Total synthesis of (.+-.)-dysidin, a marine metabolite containing an N-acyl-O-methyltetramic acid

Pyrroles and other heterocycles as inhibitors of P38 kinase

Total synthesis of halogenated monoterpene marine natural products via the Diels-Alder reaction

Deprotection of N- tert-butoxycarbonyl (Boc) groups in the presence of tert-butyl esters

The synthesis of (2S,4S,5S) -5-(N-BOC)-amino-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid lactone, an hydroxyethylene dipeptide isostere precusor

Molecular Basis for p38 Protein Kinase Inhibitor Specificity

Carbohydroxamido-oxazolidines: antibacterial agents that target lipid A biosynthesis

Total synthesis of (+)-demethyldysidenin and (-)-demethylisodysidenin, hexachlorinated amino acids from the marine sponge Dysidea herbacea. Assignment of absolute stereochemistry

Alpha(4)beta(7)/alpha(4)beta(1) dual integrin antagonists block alpha(4)beta(7)-dependent adhesion under shear flow

A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence

The Discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists

CorrigendumCorrigendum to “The discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists”[Bioorg. Med. Chem. Lett. 12 (2002) 611]

Synthesis of costatolide, a halogenated monoterpenoid from the red alga Plocamium costatum

The design, binding affinity prediction and synthesis of macrocyclic angiotensin II AT1 and AT2 receptor antagonists

Molecular Basis for p38 Protein Kinase Inhibitor Specificity

The SAR of 6-(N-alkyl-N-acyl)-2-propyl-3-[(2′-tetrazol-5-yl)biphen-4-yl)methyl]-quinazolinones as balanced affinity antagonists of the human AT1 and AT2 receptors

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