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Pyrazolopyrimidines Establish MurC as a Vulnerable Target in Pseudomonas aeruginosa and Escherichia coli

ACS chemical biology, 2014-10, Vol.9 (10), p.2274-2282

2014

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In Vitro Susceptibility of Global Surveillance Isolates of Pseudomonas aeruginosa to Ceftazidime-Avibactam (INFORM 2012 to 2014)

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4743-4749

2016

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In Vitro Susceptibility to Ceftazidime-Avibactam of Carbapenem-Nonsusceptible Enterobacteriaceae Isolates Collected during the INFORM Global Surveillance Study (2012 to 2014)

Antimicrobial agents and chemotherapy, 2016-05, Vol.60 (5), p.3163-3169

2016

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Epidemiology of Carbapenem Resistance Determinants Identified in Meropenem-Nonsusceptible Enterobacterales Collected as Part of a Global Surveillance Program, 2012 to 2017

Antimicrobial agents and chemotherapy, 2021-06, Vol.65 (7), p.e0200020-e0200020

2021

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In Vitro Activity of Aztreonam-Avibactam against Enterobacteriaceae and Pseudomonas aeruginosa Isolated by Clinical Laboratories in 40 Countries from 2012 to 2015

Antimicrobial agents and chemotherapy, 2017-09, Vol.61 (9)

2017

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Longitudinal analysis of ESBL and carbapenemase carriage among Enterobacterales and Pseudomonas aeruginosa isolates collected in Europe as part of the International Network for Optimal Resistance Monitoring (INFORM) global surveillance programme, 2013–17

Journal of antimicrobial chemotherapy, 2020-05, Vol.75 (5), p.1165-1173

2020

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In Vitro Activity of Ceftazidime-Avibactam and Aztreonam-Avibactam against OXA-48-Carrying Enterobacteriaceae Isolated as Part of the International Network for Optimal Resistance Monitoring (INFORM) Global Surveillance Program from 2012 to 2015

Antimicrobial agents and chemotherapy, 2018-12, Vol.62 (12)

2018

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Global Dissemination of blaKPC into Bacterial Species beyond Klebsiella pneumoniae and In Vitro Susceptibility to Ceftazidime-Avibactam and Aztreonam-Avibactam

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4490-4500

2016

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In Vitro Activity of Ceftazidime-Avibactam against Clinical Isolates of Enterobacteriaceae and Pseudomonas aeruginosa Collected in Asia-Pacific Countries: Results from the INFORM Global Surveillance Program, 2012 to 2015

Antimicrobial agents and chemotherapy, 2018-07, Vol.62 (7)

2018

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In vitro activity of ceftazidime/avibactam against isolates of Pseudomonas aeruginosa collected in European countries: INFORM global surveillance 2012-15

Journal of antimicrobial chemotherapy, 2018-10, Vol.73 (10), p.2777-2781

2018

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Frequency and Mechanism of Spontaneous Resistance to Sulbactam Combined with the Novel β-Lactamase Inhibitor ETX2514 in Clinical Isolates of Acinetobacter baumannii

Antimicrobial agents and chemotherapy, 2018-02, Vol.62 (2)

2018

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In Vitro Activity of Ceftazidime-Avibactam against Clinical Isolates of Enterobacteriaceae and Pseudomonas aeruginosa Collected in Latin American Countries: Results from the INFORM Global Surveillance Program, 2012 to 2015

Antimicrobial agents and chemotherapy, 2019-04, Vol.63 (4)

2019

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In vitro activity of ceftazidime/avibactam against isolates of Enterobacteriaceae collected in European countries: INFORM global surveillance 2012-15

Journal of antimicrobial chemotherapy, 2018-10, Vol.73 (10), p.2782-2788

2018

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Assessment of the In Vitro Activity of Ceftazidime-Avibactam against Multidrug-Resistant Klebsiella spp. Collected in the INFORM Global Surveillance Study, 2012 to 2014

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4677-4683

2016

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Discovery of Inhibitors of 4′-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy

Antimicrobial Agents and Chemotherapy, 2013-12, Vol.57 (12), p.6005-6015

2013

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Exploitation of structural and regulatory diversity in glutamate racemases

Nature, 2007-06, Vol.447 (7146), p.817-822

2007

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In Vitro Activity of AZD0914, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor, against Clinically Relevant Gram-Positive and Fastidious Gram-Negative Pathogens

Antimicrobial agents and chemotherapy, 2015-10, Vol.59 (10), p.6053-6063

2015

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A novel high-throughput cell-based assay aimed at identifying inhibitors of DNA metabolism in bacteria

Antimicrobial agents and chemotherapy, 2014-12, Vol.58 (12), p.7264-7272

2014

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Pyridodiazepine amines are selective therapeutic agents for helicobacter pylori by suppressing growth through inhibition of glutamate racemase but are predicted to require continuous elevated levels in plasma to achieve clinical efficacy

Antimicrobial agents and chemotherapy, 2015-04, Vol.59 (4), p.2337-2342

2015

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Compound Efflux in Helicobacter pylori

Antimicrobial Agents and Chemotherapy, 2005-07, Vol.49 (7), p.3009-3010

2005

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The Carboxyl Terminus of Peptidoglycan Stem Peptides Is a Determinant for Methicillin Resistance in Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2002-10, Vol.46 (10), p.3151-3155

2002

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Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. The role of penicillin binding protein 2A

The Journal of biological chemistry, 1992-06, Vol.267 (16), p.11248-11254

1992

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The Staphylococcus aureus scdA gene: a novel locus that affects cell division and morphogenesis

Microbiology (Society for General Microbiology), 1997-09, Vol.143 ( Pt 9) (9), p.2877-2882

1997

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Structural Characterization of an Abnormally Cross-linked Muropeptide Dimer That Is Accumulated in the Peptidoglycan of Methicillin- and Cefotaxime-resistant Mutants of Staphylococcus aureus

The Journal of biological chemistry, 1997-11, Vol.272 (46), p.29053-29059

1997

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Peptidoglycan composition in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain

The Journal of biological chemistry, 1992-06, Vol.267 (16), p.11255-11259

1992

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Pyrazolopyrimidines Establish MurC as a Vulnerable Target in Pseudomonas aeruginosa and Escherichia coli

In Vitro Susceptibility of Global Surveillance Isolates of Pseudomonas aeruginosa to Ceftazidime-Avibactam (INFORM 2012 to 2014)

In Vitro Susceptibility to Ceftazidime-Avibactam of Carbapenem-Nonsusceptible Enterobacteriaceae Isolates Collected during the INFORM Global Surveillance Study (2012 to 2014)

Epidemiology of Carbapenem Resistance Determinants Identified in Meropenem-Nonsusceptible Enterobacterales Collected as Part of a Global Surveillance Program, 2012 to 2017

In Vitro Activity of Aztreonam-Avibactam against Enterobacteriaceae and Pseudomonas aeruginosa Isolated by Clinical Laboratories in 40 Countries from 2012 to 2015

Longitudinal analysis of ESBL and carbapenemase carriage among Enterobacterales and Pseudomonas aeruginosa isolates collected in Europe as part of the International Network for Optimal Resistance Monitoring (INFORM) global surveillance programme, 2013–17

In Vitro Activity of Ceftazidime-Avibactam and Aztreonam-Avibactam against OXA-48-Carrying Enterobacteriaceae Isolated as Part of the International Network for Optimal Resistance Monitoring (INFORM) Global Surveillance Program from 2012 to 2015

Global Dissemination of blaKPC into Bacterial Species beyond Klebsiella pneumoniae and In Vitro Susceptibility to Ceftazidime-Avibactam and Aztreonam-Avibactam

In Vitro Activity of Ceftazidime-Avibactam against Clinical Isolates of Enterobacteriaceae and Pseudomonas aeruginosa Collected in Asia-Pacific Countries: Results from the INFORM Global Surveillance Program, 2012 to 2015

In vitro activity of ceftazidime/avibactam against isolates of Pseudomonas aeruginosa collected in European countries: INFORM global surveillance 2012-15

Frequency and Mechanism of Spontaneous Resistance to Sulbactam Combined with the Novel β-Lactamase Inhibitor ETX2514 in Clinical Isolates of Acinetobacter baumannii

In Vitro Activity of Ceftazidime-Avibactam against Clinical Isolates of Enterobacteriaceae and Pseudomonas aeruginosa Collected in Latin American Countries: Results from the INFORM Global Surveillance Program, 2012 to 2015

In vitro activity of ceftazidime/avibactam against isolates of Enterobacteriaceae collected in European countries: INFORM global surveillance 2012-15

Assessment of the In Vitro Activity of Ceftazidime-Avibactam against Multidrug-Resistant Klebsiella spp. Collected in the INFORM Global Surveillance Study, 2012 to 2014

Discovery of Inhibitors of 4′-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy

Exploitation of structural and regulatory diversity in glutamate racemases

In Vitro Activity of AZD0914, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor, against Clinically Relevant Gram-Positive and Fastidious Gram-Negative Pathogens

A novel high-throughput cell-based assay aimed at identifying inhibitors of DNA metabolism in bacteria

Pyridodiazepine amines are selective therapeutic agents for helicobacter pylori by suppressing growth through inhibition of glutamate racemase but are predicted to require continuous elevated levels in plasma to achieve clinical efficacy

Compound Efflux in Helicobacter pylori

The Carboxyl Terminus of Peptidoglycan Stem Peptides Is a Determinant for Methicillin Resistance in Staphylococcus aureus

Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain. The role of penicillin binding protein 2A

The Staphylococcus aureus scdA gene: a novel locus that affects cell division and morphogenesis

Structural Characterization of an Abnormally Cross-linked Muropeptide Dimer That Is Accumulated in the Peptidoglycan of Methicillin- and Cefotaxime-resistant Mutants of Staphylococcus aureus

Peptidoglycan composition in heterogeneous Tn551 mutants of a methicillin-resistant Staphylococcus aureus strain

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