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THE 5-HT6 RECEPTOR ANTAGONIST IDALOPIRDINE (LU AE58054) AND ACETYLCHOLINESTERASE INHIBITOR DONEPEZIL HAVE SYNERGISTIC EFFECTS ON BRAIN ACTIVITY: A PHARMACOLOGICAL MRI STUDY IN THE AWAKE RAT

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P1020-P1020

2016

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Antagonism of the 5-HT6 receptor – Preclinical rationale for the treatment of Alzheimer's disease

Neuropharmacology, 2017-10, Vol.125, p.50-63

2017

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THE 5-HT6 RECEPTOR ANTAGONIST LU AE58054 ALONE AND IN COMBINATION WITH DONEPEZIL POTENTIATES GAMMA OSCILLATIONS IN RAT MEDIAL PREFRONTAL CORTEX

Alzheimer's & dementia, 2014-07, Vol.10 (4), p.P780-P781

2014

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The 5-ht6 receptor antagonist idalopirdine in combination with donepezil potentiates theta and gamma eeg oscillations in the frontal cortex of the freely moving rat

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P616-P617

2015

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SCH 23390 in the prefrontal cortex enhances the effect of apomorphine on prepulse inhibition of rats

Neuropharmacology, 2006-09, Vol.51 (3), p.438-446

2006

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Reducing falls in Parkinson's disease: interactions between donepezil and the 5‐HT6 receptor antagonist idalopirdine on falls in a rat model of impaired cognitive control of complex movements

The European journal of neuroscience, 2017-01, Vol.45 (2), p.217-231

2017

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Co-treatment with rivastigmine and idalopirdine reduces the propensity for falls in a rat model of falls in Parkinson’s disease

Psychopharmacology, 2019-06, Vol.236 (6), p.1701-1715

2019

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Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model

Journal of Alzheimer's disease, 2016-01, Vol.49 (3), p.783-795

2016

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Effects of the 5-HT6 receptor antagonist idalopirdine on extracellular levels of monoamines, glutamate and acetylcholine in the rat medial prefrontal cortex

European journal of pharmacology, 2017-03, Vol.799, p.1-6

2017

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The 5-HT6 receptor antagonist idalopirdine potentiates the effects of acetylcholinesterase inhibition on neuronal network oscillations and extracellular acetylcholine levels in the rat dorsal hippocampus

Neuropharmacology, 2016-08, Vol.107, p.351-363

2016

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Altered dopaminergic firing pattern and novelty response underlie ADHD-like behavior of SorCS2-deficient mice

Translational psychiatry, 2021-01, Vol.11 (1), p.74-74, Article 74

2021

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Antagonism of the 5-HT 6 receptor - Preclinical rationale for the treatment of Alzheimer's disease

Neuropharmacology, 2017-10, Vol.125, p.50-63

2017

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Effects of the 5-HT 6 receptor antagonist idalopirdine on extracellular levels of monoamines, glutamate and acetylcholine in the rat medial prefrontal cortex

European journal of pharmacology, 2017-03, Vol.799, p.1-6

2017

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Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)

Physiological reports, 2018-12, Vol.6 (23), p.e13920-n/a

2018

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The 5-HT6 receptor antagonist idalopirdine potentiates the effects of donepezil on gamma oscillations in the frontal cortex of anesthetized and awake rats without affecting sleep-wake architecture

Neuropharmacology, 2017-02, Vol.113, p.45-59

2017

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Glucocorticoids and Vulnerability to Psychostimulant Drugs: Toward Substrate and Mechanism

Annals of the New York Academy of Sciences, 2004-06, Vol.1018 (1), p.192-198

2004

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The Serotonin Receptor 6 Antagonist Idalopirdine and Acetylcholinesterase Inhibitor Donepezil Have Synergistic Effects on Brain Activity-A Functional MRI Study in the Awake Rat

Frontiers in pharmacology, 2017-06, Vol.8, p.279-279

2017

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The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (1), p.177-180

2014

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Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex

Acta crystallographica. Section D, Biological crystallography., 2014-02, Vol.70 (2), p.451-460

2014

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Behavioral sensitization to cocaine: cooperation between glucocorticoids and epinephrine

Psychopharmacologia, 2009-07, Vol.204 (4), p.693-703

2009

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P4‐015: The 5‐HT 6 Receptor Antagonist Idalopirdine (LU AE58054) and Acetylcholinesterase Inhibitor Donepezil have Synergistic Effects on Brain Activity: A Pharmacological MRI Study in the Awake Rat

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_21)

2016

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P2‐319: The 5‐ht 6 receptor antagonist idalopirdine in combination with donepezil potentiates theta and gamma eeg oscillations in the frontal cortex of the freely moving rat

Alzheimer's & dementia, 2015-07, Vol.11 (7S_Part_13)

2015

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Neuropharmacology of glucocorticoids: Focus on emotion, cognition and cocaine

European journal of pharmacology, 2008-05, Vol.585 (2-3), p.473-482

2008

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Hippocampal CA1 region shows differential regulation of gene expression in mice displaying extremes in behavioral sensitization to amphetamine: relevance for psychosis susceptibility?

Psychopharmacologia, 2011-10, Vol.217 (4), p.525-538

2011

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P3‐411: THE 5‐HT6 RECEPTOR ANTAGONIST LU AE58054 ALONE AND IN COMBINATION WITH DONEPEZIL POTENTIATES GAMMA OSCILLATIONS IN RAT MEDIAL PREFRONTAL CORTEX

Alzheimer's & dementia, 2014-07, Vol.10 (4S_Part_21), p.P780-P781

2014

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THE 5-HT6 RECEPTOR ANTAGONIST IDALOPIRDINE (LU AE58054) AND ACETYLCHOLINESTERASE INHIBITOR DONEPEZIL HAVE SYNERGISTIC EFFECTS ON BRAIN ACTIVITY: A PHARMACOLOGICAL MRI STUDY IN THE AWAKE RAT

Antagonism of the 5-HT6 receptor – Preclinical rationale for the treatment of Alzheimer's disease

THE 5-HT6 RECEPTOR ANTAGONIST LU AE58054 ALONE AND IN COMBINATION WITH DONEPEZIL POTENTIATES GAMMA OSCILLATIONS IN RAT MEDIAL PREFRONTAL CORTEX

The 5-ht6 receptor antagonist idalopirdine in combination with donepezil potentiates theta and gamma eeg oscillations in the frontal cortex of the freely moving rat

SCH 23390 in the prefrontal cortex enhances the effect of apomorphine on prepulse inhibition of rats

Reducing falls in Parkinson's disease: interactions between donepezil and the 5‐HT6 receptor antagonist idalopirdine on falls in a rat model of impaired cognitive control of complex movements

Co-treatment with rivastigmine and idalopirdine reduces the propensity for falls in a rat model of falls in Parkinson’s disease

Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model

Effects of the 5-HT6 receptor antagonist idalopirdine on extracellular levels of monoamines, glutamate and acetylcholine in the rat medial prefrontal cortex

The 5-HT6 receptor antagonist idalopirdine potentiates the effects of acetylcholinesterase inhibition on neuronal network oscillations and extracellular acetylcholine levels in the rat dorsal hippocampus

Altered dopaminergic firing pattern and novelty response underlie ADHD-like behavior of SorCS2-deficient mice

Antagonism of the 5-HT 6 receptor - Preclinical rationale for the treatment of Alzheimer's disease

Effects of the 5-HT 6 receptor antagonist idalopirdine on extracellular levels of monoamines, glutamate and acetylcholine in the rat medial prefrontal cortex

Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)

The 5-HT6 receptor antagonist idalopirdine potentiates the effects of donepezil on gamma oscillations in the frontal cortex of anesthetized and awake rats without affecting sleep-wake architecture

Glucocorticoids and Vulnerability to Psychostimulant Drugs: Toward Substrate and Mechanism

The Serotonin Receptor 6 Antagonist Idalopirdine and Acetylcholinesterase Inhibitor Donepezil Have Synergistic Effects on Brain Activity-A Functional MRI Study in the Awake Rat

The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin

Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex

Behavioral sensitization to cocaine: cooperation between glucocorticoids and epinephrine

P4‐015: The 5‐HT 6 Receptor Antagonist Idalopirdine (LU AE58054) and Acetylcholinesterase Inhibitor Donepezil have Synergistic Effects on Brain Activity: A Pharmacological MRI Study in the Awake Rat

P2‐319: The 5‐ht 6 receptor antagonist idalopirdine in combination with donepezil potentiates theta and gamma eeg oscillations in the frontal cortex of the freely moving rat

Neuropharmacology of glucocorticoids: Focus on emotion, cognition and cocaine

Hippocampal CA1 region shows differential regulation of gene expression in mice displaying extremes in behavioral sensitization to amphetamine: relevance for psychosis susceptibility?

P3‐411: THE 5‐HT6 RECEPTOR ANTAGONIST LU AE58054 ALONE AND IN COMBINATION WITH DONEPEZIL POTENTIATES GAMMA OSCILLATIONS IN RAT MEDIAL PREFRONTAL CORTEX

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