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Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake

Science translational medicine, 2017-06, Vol.9 (393)

2017

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Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge

PloS one, 2016-08, Vol.11 (8), p.e0161193-e0161193

2016

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From empiricism to rational design: a personal perspective of the evolution of vaccine development

Nature reviews. Immunology, 2014-07, Vol.14 (7), p.505

2014

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Vaccines for the 21st century

EMBO molecular medicine, 2014-06, Vol.6 (6), p.708-720

2014

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Technologies to address antimicrobial resistance

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (51), p.12887-12895

2018

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Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (34), p.12294-12299

2014

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Vaccines, new opportunities for a new society

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (34), p.12288-12293

2014

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Vaccines for the twenty-first century society

Nature reviews. Immunology, 2011-12, Vol.11 (12), p.865

2011

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Vaccinology in the post-COVID-19 era

Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (3)

2021

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Alum adjuvanticity: Unraveling a century old mystery

European journal of immunology, 2008-08, Vol.38 (8), p.2068-2071

2008

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Mechanism of action of licensed vaccine adjuvants

Vaccine, 2009-05, Vol.27 (25), p.3331-3334

2009

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The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect

Vaccine, 2013-07, Vol.31 (33), p.3363-3369

2013

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Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin

Journal of virology, 2016-01, Vol.90 (1), p.332-344

2016

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Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

Scientific reports, 2016-01, Vol.6 (1), p.19570-19570, Article 19570

2016

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adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (52), p.21095-21100

2013

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Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (12), p.3680-3685

2015

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MF59 and Pam3CSK4 boost adaptive responses to influenza subunit vaccine through an IFN type I-independent mechanism of action

The Journal of immunology (1950), 2012-04, Vol.188 (7), p.3088-3098

2012

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Rational design of small molecules as vaccine adjuvants

Science translational medicine, 2014-11, Vol.6 (263), p.263ra160

2014

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Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (27), p.11169-11174

2011

Volltextzugriff (PDF)

Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells

PloS one, 2017-10, Vol.12 (10), p.e0185843-e0185843

2017

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Immunology of TLR-independent vaccine adjuvants

Current opinion in immunology, 2009-06, Vol.21 (3), p.339-345

2009

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Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization

Nature communications, 2015-04, Vol.6 (1), p.6565, Article 6565

2015

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Four-component Staphylococcus aureus vaccine 4C-staph enhances Fcγ receptor expression in neutrophils and monocytes and mitigates S. aureus infection in neutropenic mice

Infection and immunity, 2015-08, Vol.83 (8), p.3157-3163

2015

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Staphylococcus aureus-dependent septic arthritis in murine knee joints: local immune response and beneficial effects of vaccination

Scientific reports, 2016-11, Vol.6 (1), p.38043-38043, Article 38043

2016

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Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake

Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge

From empiricism to rational design: a personal perspective of the evolution of vaccine development

Vaccines for the 21st century

Technologies to address antimicrobial resistance

Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

Vaccines, new opportunities for a new society

Vaccines for the twenty-first century society

Vaccinology in the post-COVID-19 era

Alum adjuvanticity: Unraveling a century old mystery

Mechanism of action of licensed vaccine adjuvants

The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect

Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus

MF59 and Pam3CSK4 boost adaptive responses to influenza subunit vaccine through an IFN type I-independent mechanism of action

Rational design of small molecules as vaccine adjuvants

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells

Immunology of TLR-independent vaccine adjuvants

Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization

Four-component Staphylococcus aureus vaccine 4C-staph enhances Fcγ receptor expression in neutrophils and monocytes and mitigates S. aureus infection in neutropenic mice

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A

Staphylococcus aureus-dependent septic arthritis in murine knee joints: local immune response and beneficial effects of vaccination

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