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Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis

Circulation (New York, N.Y.), 2015-12, Vol.132 (22), p.2134-2145

2015

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Female Sex, a Major Risk Factor for Salt-Sensitive Hypertension

Current hypertension reports, 2020-12, Vol.22 (12), p.99-99, Article 99

2020

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Perivascular Adipocytes in Vascular Disease

Arteriosclerosis, thrombosis, and vascular biology, 2019-11, Vol.39 (11), p.2220-2227

2019

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Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice

Hypertension (Dallas, Tex. 1979), 2016-05, Vol.67 (5), p.1020-1028

2016

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Dietary sodium restriction sex specifically impairs endothelial function via mineralocorticoid receptor-dependent reduction in NO bioavailability in Balb/C mice

American journal of physiology. Heart and circulatory physiology, 2021-01, Vol.320 (1), p.H211-H220

2021

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Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease

Antioxidants & redox signaling, 2021-06, Vol.34 (16), p.1319-1354

2021

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Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress

Life sciences (1973), 2019-03, Vol.221, p.29-34

2019

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Sex Differences in Mechanisms of Hypertension Associated With Obesity

Hypertension (Dallas, Tex. 1979), 2018-01, Vol.71 (1), p.15-21

2018

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Reduced Endothelial Leptin Signaling Increases Vascular Adrenergic Reactivity in a Mouse Model of Congenital Generalized Lipodystrophy

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10596

2021

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Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice

International journal of molecular sciences, 2021-10, Vol.22 (20), p.10977

2021

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Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration‐approved drugs

British journal of pharmacology, 2018-09, Vol.175 (18), p.3640-3655

2018

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Sex hormones, aging and cardiometabolic syndrome

Biology of sex differences, 2019-07, Vol.10 (1), p.30-30, Article 30

2019

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Selective deficiency in endothelial PTP1B protects from diabetes and endoplasmic reticulum stress-associated endothelial dysfunction via preventing endothelial cell apoptosis

Biomedicine & pharmacotherapy, 2020-07, Vol.127, p.110200-110200, Article 110200

2020

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Progesterone Predisposes Females to Obesity-Associated Leptin-Mediated Endothelial Dysfunction via Upregulating Endothelial MR (Mineralocorticoid Receptor) Expression

Hypertension (Dallas, Tex. 1979), 2019-09, Vol.74 (3), p.678-686

2019

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Impact of Leptin-Mediated Sympatho-Activation on Cardiovascular Function in Obese Mice

Hypertension (Dallas, Tex. 1979), 2011-08, Vol.58 (2), p.271-279

2011

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Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD‐fed mice

British journal of pharmacology, 2022-04, Vol.179 (8), p.1661-1678

2022

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Mineralocorticoid Receptor and Endothelial Dysfunction in Hypertension

Current hypertension reports, 2019-10, Vol.21 (10), p.78-5, Article 78

2019

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Protein Tyrosine Phosphatase 1B, a Major Regulator of Leptin-Mediated Control of Cardiovascular Function

Circulation (New York, N.Y.), 2009-09, Vol.120 (9), p.753-763

2009

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Long Term High Fat Diet Treatment: An Appropriate Approach to Study the Sex-Specificity of the Autonomic and Cardiovascular Responses to Obesity in Mice

Frontiers in physiology, 2017-01, Vol.8, p.32-32

2017

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Female Sex, a Major Risk Factor for Salt-Sensitive Hypertension

Current hypertension reports, 2020-10, Vol.22 (12), p.99

2020

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The regulation of aldosterone secretion by leptin: implications in obesity-related cardiovascular disease

Current opinion in nephrology and hypertension, 2018-03, Vol.27 (2), p.63-69

2018

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Perivascular adipose tissue in autoimmune rheumatic diseases

Pharmacological research, 2022-08, Vol.182, p.106354-106354, Article 106354

2022

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Midgestation Leptin Infusion Induces Characteristics of Clinical Preeclampsia in Mice, Which Is Ablated by Endothelial Mineralocorticoid Receptor Deletion

Hypertension (Dallas, Tex. 1979), 2022-07, Vol.79 (7), p.1536-1547

2022

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Reviving the use of aldosterone inhibitors in treating hypertension in obesity

American journal of physiology. Regulatory, integrative and comparative physiology, 2015-11, Vol.309 (9), p.R1065-R1067

2015

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HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor-Dependent Increases in NADPH Oxidase 1 (Nox1), C-C Chemokine Receptor Type 5 (CCR5), and Inflammation

Journal of the American Heart Association, 2020-10, Vol.9 (19), p.e018074

2020

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Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis

Female Sex, a Major Risk Factor for Salt-Sensitive Hypertension

Perivascular Adipocytes in Vascular Disease

Leptin Induces Hypertension and Endothelial Dysfunction via Aldosterone-Dependent Mechanisms in Obese Female Mice

Dietary sodium restriction sex specifically impairs endothelial function via mineralocorticoid receptor-dependent reduction in NO bioavailability in Balb/C mice

Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease

Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress

Sex Differences in Mechanisms of Hypertension Associated With Obesity

Reduced Endothelial Leptin Signaling Increases Vascular Adrenergic Reactivity in a Mouse Model of Congenital Generalized Lipodystrophy

Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration‐approved drugs

Sex hormones, aging and cardiometabolic syndrome

Selective deficiency in endothelial PTP1B protects from diabetes and endoplasmic reticulum stress-associated endothelial dysfunction via preventing endothelial cell apoptosis

Progesterone Predisposes Females to Obesity-Associated Leptin-Mediated Endothelial Dysfunction via Upregulating Endothelial MR (Mineralocorticoid Receptor) Expression

Impact of Leptin-Mediated Sympatho-Activation on Cardiovascular Function in Obese Mice

Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD‐fed mice

Mineralocorticoid Receptor and Endothelial Dysfunction in Hypertension

Protein Tyrosine Phosphatase 1B, a Major Regulator of Leptin-Mediated Control of Cardiovascular Function

Long Term High Fat Diet Treatment: An Appropriate Approach to Study the Sex-Specificity of the Autonomic and Cardiovascular Responses to Obesity in Mice

Female Sex, a Major Risk Factor for Salt-Sensitive Hypertension

The regulation of aldosterone secretion by leptin: implications in obesity-related cardiovascular disease

Perivascular adipose tissue in autoimmune rheumatic diseases

Midgestation Leptin Infusion Induces Characteristics of Clinical Preeclampsia in Mice, Which Is Ablated by Endothelial Mineralocorticoid Receptor Deletion

Reviving the use of aldosterone inhibitors in treating hypertension in obesity

HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor-Dependent Increases in NADPH Oxidase 1 (Nox1), C-C Chemokine Receptor Type 5 (CCR5), and Inflammation

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