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A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion

Nature communications, 2024-06, Vol.15 (1), p.4866-17, Article 4866

2024

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The long-term effect of mTOR inhibition on lipid and glucose metabolism in tuberous sclerosis complex: data from the Dutch TSC registry

Orphanet journal of rare diseases, 2022-07, Vol.17 (1), p.252-252, Article 252

2022

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Evolution of the TOR Pathway

Journal of molecular evolution, 2011-10, Vol.73 (3-4), p.209-220

2011

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Metabolic Alterations in NADSYN1-Deficient Cells

Metabolites, 2023-12, Vol.13 (12), p.1196

2023

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A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization

PloS one, 2018-11, Vol.13 (11), p.e0207159-e0207159

2018

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Direct Infusion Mass Spectrometry to Rapidly Map Metabolic Flux of Substrates Labeled with Stable Isotopes

Metabolites, 2024-05, Vol.14 (5), p.246

2024

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

Nature (London), 1998-12, Vol.396 (6710), p.474-477

1998

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Rheb and mammalian target of rapamycin in mitochondrial homoeostasis

Open biology, 2013-12, Vol.3 (12), p.130185-130185

2013

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CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

Neuron (Cambridge, Mass.), 2013-09, Vol.79 (6), p.1169-1182

2013

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Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress

Brain pathology (Zurich, Switzerland), 2021-09, Vol.31 (5), p.e12949-n/a

2021

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Rap1A-Deficient T and B Cells Show Impaired Integrin-Mediated Cell Adhesion

Molecular and Cellular Biology, 2006-01, Vol.26 (2), p.643-653

2006

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Amino Acids Mediate mTOR/Raptor Signaling through Activation of Class 3 Phosphatidylinositol 3OH-Kinase

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (40), p.14238-14243

2005

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Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy

JAMA neurology, 2019-03, Vol.76 (3), p.342

2019

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Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity

BMC evolutionary biology, 2010-02, Vol.10, p.55

2010

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Ras and macropinocytosis： trick and treat

Cell research, 2013-08, Vol.23 (8), p.982-983

2013

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Rap1 Signaling Is Required for Suppression of Ras-Generated Reactive Oxygen Species and Protection Against Oxidative Stress in T Lymphocytes

The Journal of immunology (1950), 2004-07, Vol.173 (2), p.920-931

2004

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Mammalian target of rapamycin complex I (mTORC1) activity in ras homologue enriched in brain (Rheb)-deficient mouse embryonic fibroblasts

PloS one, 2013-11, Vol.8 (11), p.e81649-e81649

2013

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Rheb and Rags come together at the lysosome to activate mTORC1

Biochemical Society transactions, 2013-08, Vol.41 (4), p.951

2013

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Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP

Oncogene, 2005-03, Vol.24 (12), p.2087-2095

2005

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Maintenance of cellular vitamin B6 levels and mitochondrial oxidative function depend on pyridoxal 5′-phosphate homeostasis protein

The Journal of biological chemistry, 2023-09, Vol.299 (9), p.105047-105047, Article 105047

2023

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Pyridox(am)ine 5′-phosphate oxidase (PNPO) deficiency in zebrafish results in fatal seizures and metabolic aberrations

Biochimica et biophysica acta. Molecular basis of disease, 2020-03, Vol.1866 (3), p.165607-165607, Article 165607

2020

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Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines

Molecular & cellular proteomics, 2022-09, Vol.21 (9), p.100263, Article 100263

2022

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The malate-aspartate shuttle is important for de novo serine biosynthesis

Cell reports (Cambridge), 2023-09, Vol.42 (9), p.113043-113043, Article 113043

2023

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Rap1 Regulates E-cadherin-mediated Cell-Cell Adhesion

The Journal of biological chemistry, 2004-08, Vol.279 (34), p.35127-35132

2004

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A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion

The long-term effect of mTOR inhibition on lipid and glucose metabolism in tuberous sclerosis complex: data from the Dutch TSC registry

Evolution of the TOR Pathway

Metabolic Alterations in NADSYN1-Deficient Cells

A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization

Direct Infusion Mass Spectrometry to Rapidly Map Metabolic Flux of Substrates Labeled with Stable Isotopes

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

Rheb and mammalian target of rapamycin in mitochondrial homoeostasis

CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress

Rap1A-Deficient T and B Cells Show Impaired Integrin-Mediated Cell Adhesion

Amino Acids Mediate mTOR/Raptor Signaling through Activation of Class 3 Phosphatidylinositol 3OH-Kinase

Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy

Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity

Ras and macropinocytosis： trick and treat

Rap1 Signaling Is Required for Suppression of Ras-Generated Reactive Oxygen Species and Protection Against Oxidative Stress in T Lymphocytes

Mammalian target of rapamycin complex I (mTORC1) activity in ras homologue enriched in brain (Rheb)-deficient mouse embryonic fibroblasts

Rheb and Rags come together at the lysosome to activate mTORC1

Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP

Maintenance of cellular vitamin B6 levels and mitochondrial oxidative function depend on pyridoxal 5′-phosphate homeostasis protein

Pyridox(am)ine 5′-phosphate oxidase (PNPO) deficiency in zebrafish results in fatal seizures and metabolic aberrations

Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines

The malate-aspartate shuttle is important for de novo serine biosynthesis

GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay

Rap1 Regulates E-cadherin-mediated Cell-Cell Adhesion

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