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Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment

mAbs, 2020-01, Vol.12 (1), p.1682866

2020

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Binding and functional profiling of antibody mutants guides selection of optimal candidates as antibody drug conjugates

PloS one, 2019-12, Vol.14 (12), p.e0226593

2019

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Isolation of TGF-β-neutralizing single-domain antibodies of predetermined epitope specificity using next-generation DNA sequencing

Protein engineering, design and selection, 2016-10, Vol.29 (10), p.439-443

2016

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Engineering and therapeutic application of single-chain bivalent TGF-β family traps

Molecular cancer therapeutics, 2012-07, Vol.11 (7), p.1477-1487

2012

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Analysis of the contribution of receptor subdomains to the cooperative binding and internalization of transforming growth factor-β (TGF-β) type I and type II receptors

Experimental cell research, 2008-08, Vol.314 (14), p.2553-2568

2008

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Abstract PO-049: Exploiting tumor acidic microenvironment for improved therapeutics

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (21_Supplement), p.PO-049-PO-049

2020

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Predominant Intracellular Localization of the Type I Transforming Growth Factor-β Receptor and Increased Nuclear Accumulation after Growth Arrest

Experimental cell research, 2000-07, Vol.258 (1), p.121-134

2000

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Identification of a functional site on the type I TGF-β receptor by mutational analysis of its ectodomain

FEBS letters, 2002-02, Vol.513 (2-3), p.147-152

2002

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Identification of a major regulatory sequence in the latency associated transcript (LAT) promoter of herpes simplex virus type 1 (HSV-1)

Virology (New York, N.Y.), 1991-05, Vol.182 (1), p.287-297

1991

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Analysis of the contribution of receptor subdomains to the cooperative binding and internalization of transforming growth factor-[beta] (TGF-[beta]) type I and type II receptors

Experimental cell research, 2008-08, Vol.314 (14), p.2553

2008

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Transforming growth factor (TGF)-beta 1 internalization: modulation by ligand interaction with TGF-beta receptors types I and II and a mechanism that is distinct from clathrin-mediated endocytosis

The Journal of biological chemistry, 2001-07, Vol.276 (29), p.27237-27245

2001

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Molecular diversity in the adenylylcyclase family. Evidence for eight forms of the enzyme and cloning of type VI

The Journal of biological chemistry, 1992-12, Vol.267 (34), p.24858-24862

1992

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Down-regulation of Transforming Growth Factor-β Receptors: Cooperativity between the Types I, II, and III Receptors and Modulation at the Cell Surface

Experimental cell research, 1999-11, Vol.252 (2), p.352-362

1999

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Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript

Journal of Virology, 1990-10, Vol.64 (10), p.5019-5028

1990

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Transforming Growth Factor (TGF)-Î²1 Internalization

The Journal of biological chemistry, 2001-07, Vol.276 (29), p.27237

2001

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Transforming Growth Factor (TGF)-β1 Internalization

The Journal of biological chemistry, 2001-07, Vol.276 (29), p.27237-27245

2001

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The nucleotide sequence of herpes simplex virus type 2 (333) glycoprotein gB2 and analysis of predicted antigenic sites

Canadian journal of microbiology, 1987-10, Vol.33 (10), p.879-887

1987

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A role for cAMP in angiotensin II mediated inhibition of cell growth in AT1A receptor-transfected CHO-K1 cells

Molecular and cellular biochemistry, 1995-11, Vol.152 (1), p.77-86

1995

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Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment

mAbs, 2020, Vol.12 (1)

2020

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The use of lectin affinity columns for selection of precursor or fully glycosylated forms of glycoprotein gD1 of herpes simplex virus type 1

Journal of virological methods, 1988-05, Vol.20 (1), p.21-32

1988

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What's wrong with our schools: And how we can fix them

Rowman & Littlefield Education, 2010

2010

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Adenovirus-delivered antisense RNA and shRNA exhibit different silencing efficiencies for the endogenous transforming growth factor-beta (TGF-beta) type II receptor

Oligonucleotides, 2006-01, Vol.16 (1), p.2-14

2006

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Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment

Binding and functional profiling of antibody mutants guides selection of optimal candidates as antibody drug conjugates

Isolation of TGF-β-neutralizing single-domain antibodies of predetermined epitope specificity using next-generation DNA sequencing

Engineering and therapeutic application of single-chain bivalent TGF-β family traps

Analysis of the contribution of receptor subdomains to the cooperative binding and internalization of transforming growth factor-β (TGF-β) type I and type II receptors

Abstract PO-049: Exploiting tumor acidic microenvironment for improved therapeutics

Predominant Intracellular Localization of the Type I Transforming Growth Factor-β Receptor and Increased Nuclear Accumulation after Growth Arrest

Identification of a functional site on the type I TGF-β receptor by mutational analysis of its ectodomain

Identification of a major regulatory sequence in the latency associated transcript (LAT) promoter of herpes simplex virus type 1 (HSV-1)

Analysis of the contribution of receptor subdomains to the cooperative binding and internalization of transforming growth factor-[beta] (TGF-[beta]) type I and type II receptors

Transforming growth factor (TGF)-beta 1 internalization: modulation by ligand interaction with TGF-beta receptors types I and II and a mechanism that is distinct from clathrin-mediated endocytosis

Molecular diversity in the adenylylcyclase family. Evidence for eight forms of the enzyme and cloning of type VI

Down-regulation of Transforming Growth Factor-β Receptors: Cooperativity between the Types I, II, and III Receptors and Modulation at the Cell Surface

Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript

Transforming Growth Factor (TGF)-Î²1 Internalization

Transforming Growth Factor (TGF)-β1 Internalization

The nucleotide sequence of herpes simplex virus type 2 (333) glycoprotein gB2 and analysis of predicted antigenic sites

A role for cAMP in angiotensin II mediated inhibition of cell growth in AT1A receptor-transfected CHO-K1 cells

Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment

The use of lectin affinity columns for selection of precursor or fully glycosylated forms of glycoprotein gD1 of herpes simplex virus type 1

What's wrong with our schools: And how we can fix them

Adenovirus-delivered antisense RNA and shRNA exhibit different silencing efficiencies for the endogenous transforming growth factor-beta (TGF-beta) type II receptor

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