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Tedizolid for the Management of Human Infections: In Vitro Characteristics

Clinical infectious diseases, 2014-01, Vol.58 (suppl_1), p.S35-S42

2014

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Besifloxacin, a Novel Fluoroquinolone, Has Broad-Spectrum In Vitro Activity against Aerobic and Anaerobic Bacteria

Antimicrobial Agents and Chemotherapy, 2009-08, Vol.53 (8), p.3552-3560

2009

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In Vitro Activities of Linezolid Combined with Other Antimicrobial Agents against Staphylococci, Enterococci, Pneumococci, and Selected Gram-Negative Organisms

Antimicrobial Agents and Chemotherapy, 2003-06, Vol.47 (6), p.1902-1906

2003

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Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

Journal of medicinal chemistry, 1996-02, Vol.39 (3), p.673-679

1996

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Discovery and Characterization of QPT-1, the Progenitor of a New Class of Bacterial Topoisomerase Inhibitors

Antimicrobial Agents and Chemotherapy, 2008-08, Vol.52 (8), p.2806-2812

2008

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Oxazolidinones: a new class of antibacterials

Current Opinion in Pharmacology, 2001-10, Vol.1 (5), p.470-476

2001

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Novel oxazolidinone–quinolone hybrid antimicrobials

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4213-4216

2003

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Ribosomes from an Oxazolidinone-Resistant Mutant Confer Resistance to Eperezolid in a Staphylococcus aureus Cell-Free Transcription-Translation Assay

Antimicrobial Agents and Chemotherapy, 1998-04, Vol.42 (4), p.947-950

1998

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Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity

Journal of medicinal chemistry, 1996-02, Vol.39 (3), p.680-685

1996

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Pharmacokinetics and Efficacy of Linezolid in a Gerbil Model of Streptococcus pneumoniae-Induced Acute Otitis Media

Antimicrobial Agents and Chemotherapy, 2003-04, Vol.47 (4), p.1355-1363

2003

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The synthesis and antibacterial activity of 1,3,4-Thiadiazole phenyl oxazolidinone analogues

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4193-4196

2003

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Identification of Phenylisoxazolines as Novel and Viable Antibacterial Agents Active against Gram-Positive Pathogens

Journal of medicinal chemistry, 2003-01, Vol.46 (2), p.284-302

2003

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Bacterial translation inhibitors, 1-acylindazol-3-ols as anthranilic acid mimics

Bioorganic & medicinal chemistry letters, 2008-12, Vol.18 (23), p.6293-6297

2008

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Structure–activity relationships of bioisosteres of a carboxylic acid in a novel class of bacterial translation inhibitors

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (14), p.4040-4043

2007

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Preparation of novel anthranilic acids as antibacterial agents. Extensive evaluation of alternative amide bioisosteres connecting the A- and the B-rings

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (10), p.2823-2827

2007

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Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2347-2350

2007

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Preparation of novel anthranilic acids as antibacterial agents: Extensive evaluation of structural and physical properties on antibacterial activity and human serum albumin affinity

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3113-3116

2007

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New Antibacterial tetrahydro-4(2 H)-thiopyran and thiomorpholine S-oxide and S, S-dioxide phenyloxazolidinones

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4209-4212

2003

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Piperazinyl Oxazolidinone Antibacterial Agents Containing a Pyridine, Diazene, or Triazene Heteroaromatic Ring

Journal of medicinal chemistry, 1998-09, Vol.41 (19), p.3727-3735

1998

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Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4197-4200

2003

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Correlation of carboxylic acid pKa to protein binding and antibacterial activity of a novel class of bacterial translation inhibitors

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (19), p.5479-5482

2007

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The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4235-4239

2003

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3-arylpiperidines as potentiators of existing antibacterial agents

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (14), p.1903-1906

2001

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Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.953-970

2000

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Tedizolid for the Management of Human Infections: In Vitro Characteristics

Besifloxacin, a Novel Fluoroquinolone, Has Broad-Spectrum In Vitro Activity against Aerobic and Anaerobic Bacteria

In Vitro Activities of Linezolid Combined with Other Antimicrobial Agents against Staphylococci, Enterococci, Pneumococci, and Selected Gram-Negative Organisms

Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

Discovery and Characterization of QPT-1, the Progenitor of a New Class of Bacterial Topoisomerase Inhibitors

Oxazolidinones: a new class of antibacterials

Novel oxazolidinone–quinolone hybrid antimicrobials

Ribosomes from an Oxazolidinone-Resistant Mutant Confer Resistance to Eperezolid in a Staphylococcus aureus Cell-Free Transcription-Translation Assay

Identification of a Novel Oxazolidinone (U-100480) with Potent Antimycobacterial Activity

Pharmacokinetics and Efficacy of Linezolid in a Gerbil Model of Streptococcus pneumoniae-Induced Acute Otitis Media

The synthesis and antibacterial activity of 1,3,4-Thiadiazole phenyl oxazolidinone analogues

Identification of Phenylisoxazolines as Novel and Viable Antibacterial Agents Active against Gram-Positive Pathogens

Antibacterial Oxazolidinones Possessing a Novel C-5 Side Chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic Acid Amide (PF-00422602), a New Lead Compound

Bacterial translation inhibitors, 1-acylindazol-3-ols as anthranilic acid mimics

Structure–activity relationships of bioisosteres of a carboxylic acid in a novel class of bacterial translation inhibitors

Preparation of novel anthranilic acids as antibacterial agents. Extensive evaluation of alternative amide bioisosteres connecting the A- and the B-rings

Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles

Preparation of novel anthranilic acids as antibacterial agents: Extensive evaluation of structural and physical properties on antibacterial activity and human serum albumin affinity

New Antibacterial tetrahydro-4(2 H)-thiopyran and thiomorpholine S-oxide and S, S-dioxide phenyloxazolidinones

Piperazinyl Oxazolidinone Antibacterial Agents Containing a Pyridine, Diazene, or Triazene Heteroaromatic Ring

Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials

Correlation of carboxylic acid pKa to protein binding and antibacterial activity of a novel class of bacterial translation inhibitors

The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones

3-arylpiperidines as potentiators of existing antibacterial agents

Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

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