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Future avenues for Alzheimer's disease detection and therapy: liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery

Neuropharmacology, 2021-03, Vol.185, p.108081-108081, Article 108081

2021

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Small GTPases of the Rab and Arf Families: Key Regulators of Intracellular Trafficking in Neurodegeneration

International journal of molecular sciences, 2021-04, Vol.22 (9), p.4425

2021

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Amyloid β / PKC-dependent alterations in NMDA receptor composition are detected in early stages of Alzheimer´s disease

Cell death & disease, 2022-03, Vol.13 (3), p.253-253, Article 253

2022

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An overview of international regulatory frameworks for mesenchymal stromal cell‐based medicinal products: From laboratory to patient

Medicinal research reviews, 2020-07, Vol.40 (4), p.1315-1334

2020

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Rac1/p21‐activated kinase pathway controls retinoblastoma protein phosphorylation and E2F transcription factor activation in B lymphocytes

The FEBS journal, 2016-02, Vol.283 (4), p.647-661

2016

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H-Chain Ferritin: A Natural Nuclei Targeting and Bioactive Delivery Nanovector

Advanced healthcare materials, 2015-06, Vol.4 (9), p.1305-1310

2015

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Successful aging: insights from proteome analyses of healthy centenarians

Aging (Albany, NY.), 2020-02, Vol.12 (4), p.3502-3515

2020

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Identification of Potential Muscle Biomarkers in McArdle Disease: Insights from Muscle Proteome Analysis

International journal of molecular sciences, 2022-04, Vol.23 (9), p.4650

2022

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Lck/PLCγ control migration and proliferation of interleukin (IL)-2-stimulated T cells via the Rac1 GTPase/glycogen phosphorylase pathway

Cellular signalling, 2016-11, Vol.28 (11), p.1713-1724

2016

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Epidermal growth factor receptor controls glycogen phosphorylase in T cells through small GTPases of the RAS family

The Journal of biological chemistry, 2019-03, Vol.294 (12), p.4345-4358

2019

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Recombinant Integrin β1 Signal Peptide Blocks Gliosis Induced by Aβ Oligomers

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5747

2022

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Muscle molecular adaptations to endurance exercise training are conditioned by glycogen availability: a proteomics‐based analysis in the McArdle mouse model

The Journal of physiology, 2018-03, Vol.596 (6), p.1035-1061

2018

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Exercise Benefits in Pulmonary Hypertension

Journal of the American College of Cardiology, 2019-06, Vol.73 (22), p.2906-2907

2019

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Mesenchymal Stem Cells as Therapeutics Agents: Quality and Environmental Regulatory Aspects

Stem cells international, 2016-01, Vol.2016 (1), p.9783408

2016

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Guanine Nucleotide Exchange Factor αPIX Leads to Activation of the Rac 1 GTPase/Glycogen Phosphorylase Pathway in Interleukin (IL)-2-stimulated T Cells

The Journal of biological chemistry, 2015-04, Vol.290 (14), p.9171-9182

2015

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Rac1 Protein Regulates Glycogen Phosphorylase Activation and Controls Interleukin (IL)-2-dependent T Cell Proliferation

The Journal of biological chemistry, 2012-04, Vol.287 (15), p.11878-11890

2012

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Cell Signaling in Neurodegeneration

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8978

Zugaza, José L.

2021

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PLAGL1: an important player in diverse pathological processes

Journal of applied genetics, 2017-02, Vol.58 (1), p.71-78

2017

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Crosstalk between Rap1 and Rac regulates secretion of sAPPα

Nature cell biology, 2003-07, Vol.5 (7), p.633-639

2003

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Exchange Factors of the RasGRP Family Mediate Ras Activation in the Golgi

The Journal of biological chemistry, 2003-08, Vol.278 (35), p.33465-33473

2003

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Epac signaling pathway involves STEF, a guanine nucleotide exchange factor for Rac, to regulate APP processing

FEBS letters, 2007-12, Vol.581 (30), p.5814-5818

2007

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Expression of the DYRK1A gene correlates with its 3D positioning in the interphase nucleus of Down syndrome cells

Chromosome research, 2015-06, Vol.23 (2), p.285-298

2015

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The interaction between Cdc42 and WASP is required for SDF-1–induced T-lymphocyte chemotaxis

Blood, 2001-01, Vol.97 (1), p.33-38

2001

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Mechanistic Analysis of the Amplification and Diversification Events Induced by Vav Proteins in B-lymphocytes

The Journal of biological chemistry, 2008-12, Vol.283 (52), p.36454-36464

2008

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Structural Determinants for the Biological Activity of Vav Proteins

The Journal of biological chemistry, 2002-11, Vol.277 (47), p.45377-45392

2002

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Future avenues for Alzheimer's disease detection and therapy: liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery

Small GTPases of the Rab and Arf Families: Key Regulators of Intracellular Trafficking in Neurodegeneration

Amyloid β / PKC-dependent alterations in NMDA receptor composition are detected in early stages of Alzheimer´s disease

An overview of international regulatory frameworks for mesenchymal stromal cell‐based medicinal products: From laboratory to patient

Rac1/p21‐activated kinase pathway controls retinoblastoma protein phosphorylation and E2F transcription factor activation in B lymphocytes

H-Chain Ferritin: A Natural Nuclei Targeting and Bioactive Delivery Nanovector

Successful aging: insights from proteome analyses of healthy centenarians

Identification of Potential Muscle Biomarkers in McArdle Disease: Insights from Muscle Proteome Analysis

Lck/PLCγ control migration and proliferation of interleukin (IL)-2-stimulated T cells via the Rac1 GTPase/glycogen phosphorylase pathway

Epidermal growth factor receptor controls glycogen phosphorylase in T cells through small GTPases of the RAS family

Recombinant Integrin β1 Signal Peptide Blocks Gliosis Induced by Aβ Oligomers

Muscle molecular adaptations to endurance exercise training are conditioned by glycogen availability: a proteomics‐based analysis in the McArdle mouse model

Exercise Benefits in Pulmonary Hypertension

Mesenchymal Stem Cells as Therapeutics Agents: Quality and Environmental Regulatory Aspects

Guanine Nucleotide Exchange Factor αPIX Leads to Activation of the Rac 1 GTPase/Glycogen Phosphorylase Pathway in Interleukin (IL)-2-stimulated T Cells

Rac1 Protein Regulates Glycogen Phosphorylase Activation and Controls Interleukin (IL)-2-dependent T Cell Proliferation

Cell Signaling in Neurodegeneration

PLAGL1: an important player in diverse pathological processes

Crosstalk between Rap1 and Rac regulates secretion of sAPPα

Exchange Factors of the RasGRP Family Mediate Ras Activation in the Golgi

Epac signaling pathway involves STEF, a guanine nucleotide exchange factor for Rac, to regulate APP processing

Expression of the DYRK1A gene correlates with its 3D positioning in the interphase nucleus of Down syndrome cells

The interaction between Cdc42 and WASP is required for SDF-1–induced T-lymphocyte chemotaxis

Mechanistic Analysis of the Amplification and Diversification Events Induced by Vav Proteins in B-lymphocytes

Structural Determinants for the Biological Activity of Vav Proteins

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