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Membrane potential shapes regulation of dopamine transporter trafficking at the plasma membrane

Nature communications, 2016-01, Vol.7 (1), p.10423-10423, Article 10423

2016

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Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists

Psychopharmacology, 2012-01, Vol.219 (2), p.341-352

2012

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Relationship between Conformational Changes in the Dopamine Transporter and Cocaine-Like Subjective Effects of Uptake Inhibitors

Molecular pharmacology, 2008-03, Vol.73 (3), p.813-823

2008

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Tyr-95 and Ile-172 in Transmembrane Segments 1 and 3 of Human Serotonin Transporters Interact to Establish High Affinity Recognition of Antidepressants

The Journal of biological chemistry, 2006-01, Vol.281 (4), p.2012-2023

2006

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A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats

Addiction biology, 2014-03, Vol.19 (2), p.195-209

2014

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Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D2 Receptor (D2R) Biased Agonism

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2890-2907

2017

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Novel Analogues of (R)‑5-(Methylamino)-5,6-dihydro‑4H‑imidazo[4,5,1-ij]quinolin-2(1H)‑one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity

Journal of medicinal chemistry, 2016-04, Vol.59 (7), p.2973-2988

2016

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Probing Binding Pocket of Serotonin Transporter by Single Molecular Force Spectroscopy on Living Cells

The Journal of biological chemistry, 2012-01, Vol.287 (1), p.105-113

2012

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Structure–Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders

Journal of medicinal chemistry, 2017-12, Vol.60 (24), p.10172-10187

2017

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Visualization of Dopamine Transporter Trafficking in Live Neurons by Use of Fluorescent Cocaine Analogs

The Journal of neuroscience, 2009-05, Vol.29 (21), p.6794-6808

2009

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Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs

Biochemical pharmacology, 2017-10, Vol.142, p.204-215

2017

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2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter

The Journal of pharmacology and experimental therapeutics, 2014-05, Vol.349 (2), p.297

2014

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Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change

Psychopharmacology, 2013-09, Vol.229 (2), p.307-321

2013

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Structure−Activity Relationships Comparing N-(6-Methylpyridin-yl)-Substituted Aryl Amides to 2-Methyl-6-(substituted-arylethynyl)pyridines or 2-Methyl-4-(substituted-arylethynyl)thiazoles as Novel Metabotropic Glutamate Receptor Subtype 5 Antagonists

Journal of medicinal chemistry, 2009-06, Vol.52 (11), p.3563-3575

2009

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Design and synthesis of substituted N-(1,3-diphenyl-1 H-pyrazol-5-yl)benzamides as positive allosteric modulators of the metabotropic glutamate receptor subtype 5

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (9), p.2650-2654

2011

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Structure–activity relationships in a novel series of 7-substituted-aryl quinolines and 5-substituted-aryl benzothiazoles at the metabotropic glutamate receptor subtype 5

Bioorganic & medicinal chemistry, 2010-05, Vol.18 (9), p.3026-3035

2010

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Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators as Novel Tools for in Vivo Investigation

ACS medicinal chemistry letters, 2012-07, Vol.3 (7), p.544-549

2012

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Rhodamine-Labeled 2β-Carbomethoxy-3β-(3,4-dichlorophenyl)tropane Analogues as High-Affinity Fluorescent Probes for the Dopamine Transporter

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7513-7516

2005

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Efficient Synthesis of B-Iododialkyl- and B-Alkyldiiodoboranes as Their Acetonitrile Complexes: Application for the Enolboration-Aldolization of Ethyl Ketones

Helvetica chimica acta, 2002-10, Vol.85 (10), p.3027-3032

2002

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Structure−Activity Relationship Comparison of (S)-2β-Substituted 3α-(Bis[4-fluorophenyl]methoxy)tropanes and (R)-2β-Substituted 3β-(3,4-Dichlorophenyl)tropanes at the Dopamine Transporter

Journal of medicinal chemistry, 2003-07, Vol.46 (14), p.2908-2916

2003

Volltextzugriff (PDF)

Radioiodinated Azide and Isothiocyanate Derivatives of Cocaine for Irreversible Labeling of Dopamine Transporters: Synthesis and Covalent Binding Studies

Bioconjugate chemistry, 2005-05, Vol.16 (3), p.644-649

2005

Volltextzugriff (PDF)

Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D 2 Receptor (D 2 R) Biased Agonism

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2890-2907

2017

Volltextzugriff (PDF)

Enantioselective synthesis of S-(+)-2β-carboalkoxy-3α-[bis(4-fluorophenyl)methoxy]tropanes as novel probes for the dopamine transporter

Bioorganic & medicinal chemistry letters, 2002-05, Vol.12 (9), p.1249-1252

2002

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[ 3H]MFZ 2-12: A Novel Radioligand for the Dopamine Transporter

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (13), p.1659-1661

2001

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Efficient diastereoselective synthesis of anti-α-bromo-β-hydroxyketones

Tetrahedron letters, 1999-11, Vol.40 (45), p.7875-7877

1999

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Membrane potential shapes regulation of dopamine transporter trafficking at the plasma membrane

Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists

Relationship between Conformational Changes in the Dopamine Transporter and Cocaine-Like Subjective Effects of Uptake Inhibitors

Tyr-95 and Ile-172 in Transmembrane Segments 1 and 3 of Human Serotonin Transporters Interact to Establish High Affinity Recognition of Antidepressants

A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats

Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D2 Receptor (D2R) Biased Agonism

Novel Analogues of (R)‑5-(Methylamino)-5,6-dihydro‑4H‑imidazo[4,5,1-ij]quinolin-2(1H)‑one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity

Probing Binding Pocket of Serotonin Transporter by Single Molecular Force Spectroscopy on Living Cells

Structure–Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders

Visualization of Dopamine Transporter Trafficking in Live Neurons by Use of Fluorescent Cocaine Analogs

Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs

2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter

Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change

Structure−Activity Relationships Comparing N-(6-Methylpyridin-yl)-Substituted Aryl Amides to 2-Methyl-6-(substituted-arylethynyl)pyridines or 2-Methyl-4-(substituted-arylethynyl)thiazoles as Novel Metabotropic Glutamate Receptor Subtype 5 Antagonists

Design and synthesis of substituted N-(1,3-diphenyl-1 H-pyrazol-5-yl)benzamides as positive allosteric modulators of the metabotropic glutamate receptor subtype 5

Structure–activity relationships in a novel series of 7-substituted-aryl quinolines and 5-substituted-aryl benzothiazoles at the metabotropic glutamate receptor subtype 5

Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators as Novel Tools for in Vivo Investigation

Rhodamine-Labeled 2β-Carbomethoxy-3β-(3,4-dichlorophenyl)tropane Analogues as High-Affinity Fluorescent Probes for the Dopamine Transporter

Efficient Synthesis of B-Iododialkyl- and B-Alkyldiiodoboranes as Their Acetonitrile Complexes: Application for the Enolboration-Aldolization of Ethyl Ketones

Structure−Activity Relationship Comparison of (S)-2β-Substituted 3α-(Bis[4-fluorophenyl]methoxy)tropanes and (R)-2β-Substituted 3β-(3,4-Dichlorophenyl)tropanes at the Dopamine Transporter

Radioiodinated Azide and Isothiocyanate Derivatives of Cocaine for Irreversible Labeling of Dopamine Transporters: Synthesis and Covalent Binding Studies

Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D 2 Receptor (D 2 R) Biased Agonism

Enantioselective synthesis of S-(+)-2β-carboalkoxy-3α-[bis(4-fluorophenyl)methoxy]tropanes as novel probes for the dopamine transporter

[ 3H]MFZ 2-12: A Novel Radioligand for the Dopamine Transporter

Efficient diastereoselective synthesis of anti-α-bromo-β-hydroxyketones

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