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The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

Nature communications, 2019-01, Vol.10 (1), p.6-6, Article 6

2019

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Systematic analysis of protein turnover in primary cells

Nature communications, 2018-02, Vol.9 (1), p.689-10, Article 689

2018

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Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

Communications biology, 2020-03, Vol.3 (1), p.140, Article 140

2020

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De novo sequencing of peptides by MS/MS

Proteomics (Weinheim), 2010-02, Vol.10 (4), p.634-649

2010

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Delayed Fragmentation and Optimized Isolation Width Settings for Improvement of Protein Identification and Accuracy of Isobaric Mass Tag Quantification on Orbitrap-Type Mass Spectrometers

Analytical chemistry (Washington), 2011-12, Vol.83 (23), p.8959-8967

2011

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Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

Nature communications, 2020-09, Vol.11 (1), p.4680-4680, Article 4680

2020

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Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor

ACS medicinal chemistry letters, 2019-05, Vol.10 (5), p.780-785

2019

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Improved Proteomics-Based Drug Mechanism-of-Action Studies Using 16-Plex Isobaric Mass Tags

Journal of proteome research, 2021-03, Vol.20 (3), p.1792-1801

2021

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Gel Electrophoresis Coupled to Inductively Coupled Plasma−Mass Spectrometry Using Species-Specific Isotope Dilution for Iodide and Iodate Determination in Aerosols

Analytical chemistry (Washington), 2007-02, Vol.79 (4), p.1714-1719

2007

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Measuring and Managing Ratio Compression for Accurate iTRAQ/TMT Quantification

Journal of proteome research, 2013-08, Vol.12 (8), p.3586-3598

2013

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Biological plasticity rescues target activity in CRISPR knock outs

Nature methods, 2019-11, Vol.16 (11), p.1087-1093

2019

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Catalytic in vivo protein knockdown by small-molecule PROTACs

Nature chemical biology, 2015-08, Vol.11 (8), p.611-617

2015

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Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

Cell, 2018-03, Vol.173 (1), p.260-274.e25

2018

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Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

Angewandte Chemie International Edition, 2021-10, Vol.60 (43), p.23327-23334

International ed. in English, 2021

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An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices

The European respiratory journal, 2021-07, Vol.58 (1), p.2000221

2021

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Chemoproteomics-Based Design of Potent LRRK2-Selective Lead Compounds That Attenuate Parkinson’s Disease-Related Toxicity in Human Neurons

ACS chemical biology, 2011-10, Vol.6 (10), p.1021-1028

2011

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Mass spectrometry approaches to monitor protein–drug interactions

Methods (San Diego, Calif.), 2012-08, Vol.57 (4), p.430-440

2012

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Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2)

The Journal of biological chemistry, 2015-02, Vol.290 (7), p.4178-4191

2015

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Microquantification of phospholipid classes by stable isotope dilution and nanoESI mass spectrometry

Analytical and bioanalytical chemistry, 2016-11, Vol.408 (27), p.7663-7667

2016

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Recombinant Isotope Labeled and Selenium Quantified Proteins for Absolute Protein Quantification

Analytical chemistry (Washington), 2010-03, Vol.82 (6), p.2334-2340

2010

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Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS

ACS medicinal chemistry letters, 2018-07, Vol.9 (7), p.623-628

2018

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Preparation of heteroelement-incorporated and stable isotope-labeled protein standards for quantitative proteomics

Methods in molecular biology (Clifton, N.J.), 2014, Vol.1156, p.337

2014

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Mo1602 - Identification of a Ret Kinase Inhibitor, GSK589, as a Peripheral Analgesic for the Treatment Visceral Pain Associated with Irritable Bowel Syndrome

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S731-S731

2017

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μLC coupled to ICP-SFMS with post-column isotope dilution analysis of sulfur for absolute protein quantification

Analytical and bioanalytical chemistry, 2008-05, Vol.391 (2), p.537-543

2008

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Phosphorus-Based Absolutely Quantified Standard Peptides for Quantitative Proteomics

Journal of proteome research, 2009-10, Vol.8 (10), p.4870-4875

2009

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The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

Systematic analysis of protein turnover in primary cells

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

De novo sequencing of peptides by MS/MS

Delayed Fragmentation and Optimized Isolation Width Settings for Improvement of Protein Identification and Accuracy of Isobaric Mass Tag Quantification on Orbitrap-Type Mass Spectrometers

Author Correction: The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor

Improved Proteomics-Based Drug Mechanism-of-Action Studies Using 16-Plex Isobaric Mass Tags

Gel Electrophoresis Coupled to Inductively Coupled Plasma−Mass Spectrometry Using Species-Specific Isotope Dilution for Iodide and Iodate Determination in Aerosols

Measuring and Managing Ratio Compression for Accurate iTRAQ/TMT Quantification

Biological plasticity rescues target activity in CRISPR knock outs

Catalytic in vivo protein knockdown by small-molecule PROTACs

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis

Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices

Chemoproteomics-Based Design of Potent LRRK2-Selective Lead Compounds That Attenuate Parkinson’s Disease-Related Toxicity in Human Neurons

Mass spectrometry approaches to monitor protein–drug interactions

Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2)

Microquantification of phospholipid classes by stable isotope dilution and nanoESI mass spectrometry

Recombinant Isotope Labeled and Selenium Quantified Proteins for Absolute Protein Quantification

Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS

Preparation of heteroelement-incorporated and stable isotope-labeled protein standards for quantitative proteomics

Mo1602 - Identification of a Ret Kinase Inhibitor, GSK589, as a Peripheral Analgesic for the Treatment Visceral Pain Associated with Irritable Bowel Syndrome

μLC coupled to ICP-SFMS with post-column isotope dilution analysis of sulfur for absolute protein quantification

Phosphorus-Based Absolutely Quantified Standard Peptides for Quantitative Proteomics

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