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Tight junctions: from simple barriers to multifunctional molecular gates

Nature reviews. Molecular cell biology, 2016-09, Vol.17 (9), p.564

2016

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Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly

Cell reports (Cambridge), 2020-07, Vol.32 (3), p.107924-107924, Article 107924

2020

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Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex

The Journal of cell biology, 2012-08, Vol.198 (4), p.677-693

2012

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MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival

The Journal of cell biology, 2014-03, Vol.204 (5), p.821-838

2014

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Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation

The Journal of cell biology, 2014-01, Vol.204 (1), p.111-127

2014

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ZO-1 Regulates Hippo-Independent YAP Activity and Cell Proliferation via a GEF-H1- and TBK1-Regulated Signalling Network

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.640

2024

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ZO-1 Guides Tight Junction Assembly and Epithelial Morphogenesis via Cytoskeletal Tension-Dependent and -Independent Functions

Cells (Basel, Switzerland), 2022-11, Vol.11 (23), p.3775

2022

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MRCK: a master regulator of tissue remodeling or another 'ROCK' in the epithelial block?

Tissue barriers, 2021-07, Vol.9 (3), p.1916380-1916380

Zihni, Ceniz

2021

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Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion

PloS one, 2012-11, Vol.7 (11), p.e50188-e50188

2012

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Signalling at tight junctions during epithelial differentiation and microbial pathogenesis

Journal of cell science, 2014-08, Vol.127 (Pt 16), p.3401-3413

2014

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RhoGTPase signalling at epithelial tight junctions: Bridging the GAP between polarity and cancer

The international journal of biochemistry & cell biology, 2015-07, Vol.64, p.120-125

2015

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Prostate-derived Sterile 20-like Kinase 2 (PSK2) Regulates Apoptotic Morphology via C-Jun N-terminal Kinase and Rho Kinase-1

The Journal of biological chemistry, 2006-03, Vol.281 (11), p.7317-7323

2006

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An apical MRCK-driven morphogenetic pathway controls epithelial polarity

Nature cell biology, 2017-09, Vol.19 (9), p.1049

2017

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The Prostate-derived Sterile 20-like Kinase (PSK) Regulates Microtubule Organization and Stability

The Journal of biological chemistry, 2003-05, Vol.278 (20), p.18085-18091

2003

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Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

Nature cell biology, 2011-02, Vol.13 (2), p.159

2011

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Spatiotemporal control of actomyosin contractility by MRCKβ signaling drives phagocytosis

The Journal of cell biology, 2022-11, Vol.221 (11), p.1

2022

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Prostate-derived Sterile 20-like Kinase 1-α Induces Apoptosis: JNK- AND CASPASE-DEPENDENT NUCLEAR LOCALIZATION IS A REQUIREMENT FOR MEMBRANE BLEBBING

The Journal of biological chemistry, 2007-03, Vol.282 (9), p.6484-6493

2007

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Prostate-derived Sterile 20-like Kinase 1-α Induces Apoptosis

The Journal of biological chemistry, 2007-03, Vol.282 (9), p.6484-6493

2007

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Prostate-derived Sterile 20-like Kinase 1-Î± Induces Apoptosis

The Journal of biological chemistry, 2007-03, Vol.282 (9), p.6484

2007

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An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

FEMS immunology and medical microbiology, 1999-04, Vol.23 (4), p.289-293

1999

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The effect of adrenomedullin on growth-associated signalling pathways in vascular cells

Zihni, Ceniz

2002

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An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

FEMS immunology and medical microbiology, 1999-04, Vol.23 (4), p.289-293

1999

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Signal Transduction
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Myosin
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Tight Junctions - Metabolism
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Cytoskeleton
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Epithelial Cells - Metabolism
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Guanine Nucleotide Exchange Factors - Metabolism
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Kinases
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Caco-2 Cells
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Tight junctions: from simple barriers to multifunctional molecular gates

Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly

Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex

MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival

Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation

ZO-1 Regulates Hippo-Independent YAP Activity and Cell Proliferation via a GEF-H1- and TBK1-Regulated Signalling Network

ZO-1 Guides Tight Junction Assembly and Epithelial Morphogenesis via Cytoskeletal Tension-Dependent and -Independent Functions

MRCK: a master regulator of tissue remodeling or another 'ROCK' in the epithelial block?

Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion

Signalling at tight junctions during epithelial differentiation and microbial pathogenesis

RhoGTPase signalling at epithelial tight junctions: Bridging the GAP between polarity and cancer

Prostate-derived Sterile 20-like Kinase 2 (PSK2) Regulates Apoptotic Morphology via C-Jun N-terminal Kinase and Rho Kinase-1

An apical MRCK-driven morphogenetic pathway controls epithelial polarity

The Prostate-derived Sterile 20-like Kinase (PSK) Regulates Microtubule Organization and Stability

Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

Spatiotemporal control of actomyosin contractility by MRCKβ signaling drives phagocytosis

Prostate-derived Sterile 20-like Kinase 1-α Induces Apoptosis: JNK- AND CASPASE-DEPENDENT NUCLEAR LOCALIZATION IS A REQUIREMENT FOR MEMBRANE BLEBBING

Prostate-derived Sterile 20-like Kinase 1-α Induces Apoptosis

Prostate-derived Sterile 20-like Kinase 1-Î± Induces Apoptosis

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

The effect of adrenomedullin on growth-associated signalling pathways in vascular cells

An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora

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