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Reaction phenotyping: advances in the experimental strategies used to characterize the contribution of drug-metabolizing enzymes

Drug metabolism and disposition, 2015-01, Vol.43 (1), p.163-181

2015

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Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Clinical pharmacology and therapeutics, 2019-09, Vol.106 (3), p.525-543

2019

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Relative contributions of cytochrome CYP3A4 versus CYP3A5 for CYP3A-cleared drugs assessed in vitro using a CYP3A4-selective inactivator (CYP3cide)

Drug metabolism and disposition, 2014-07, Vol.42 (7), p.1163

2014

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Contribution of Extrahepatic Aldehyde Oxidase Activity to Human Clearance

Drug metabolism and disposition, 2021-09, Vol.49 (9), p.743-749

2021

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Strategies for a comprehensive understanding of metabolism by aldehyde oxidase

Expert opinion on drug metabolism & toxicology, 2013-02, Vol.9 (2), p.153-168

2013

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Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs

Drug metabolism and disposition, 2023-10, Vol.51 (10), p.1362

2023

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Ontogeny of Human Liver Aldehyde Oxidase: Developmental Changes and Implications for Drug Metabolism

Molecular pharmaceutics, 2024-06, Vol.21 (6), p.2740-2750

2024

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Clearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance Mechanisms

Drug metabolism and disposition, 2017-01, Vol.45 (1), p.1-7

2017

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Quantifying and predicting the promiscuity and isoform specificity of small-molecule cytochrome P450 inhibitors

Drug metabolism and disposition, 2010-12, Vol.38 (12), p.2195

2010

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The crystal structure of CYP3A4 in complex with bromocriptine

The FASEB journal, 2009-04, Vol.23 (S1)

2009

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Characterization of endothelin converting enzyme from intact cells of a permanent human endothelial cell line EA.hy926

Biochemistry and molecular biology international, 1996-06, Vol.39 (3), p.573-580

1996

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CYP and UGT inhibition to assess perpetrator drug-drug interaction potential

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100547, Article 100547

Zientek, Michael

2024

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Reaction phenotyping for UGT enzymes

Drug metabolism and pharmacokinetics, 2018-01, Vol.33 (1), p.S1-S1

Zientek, Michael

2018

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Process control with compact NMR

TrAC, Trends in analytical chemistry (Regular ed.), 2016-10, Vol.83, p.39-52

2016

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Effect of micro-plastic particles on coral reef foraminifera

Scientific reports, 2024-05, Vol.14 (1), p.12423-10, Article 12423

2024

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The Geochemical and Textural Transition between the Reef Package and its Hanging Wall, Stillwater Complex, Montana, USA

Journal of petrology, 2022-07, Vol.63 (7)

2022

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Mineral deposit discovery order and three-part quantitative assessments

Ore geology reviews, 2021-12, Vol.139, p.104566, Article 104566

2021

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Higher HbA1c levels associate with lower hippocampal serotonin transporter availability in non-diabetic adults with obesity

Scientific reports, 2020-12, Vol.10 (1), p.21383-21383, Article 21383

2020

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Are CYP3A5 expresser subpopulations at an increased risk for acetaminophen toxicity?

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S26-S26

2019

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In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase

Drug metabolism and disposition, 2010-08, Vol.38 (8), p.1322

2010

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In situ determination of Os, Ir, and Ru in chromites formed from komatiite, tholeiite and boninite magmas: Implications for chromite control of Os, Ir and Ru during partial melting and crystal fractionation

Chemical geology, 2012-04, Vol.302-303, p.3-15

2012

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Sigma-1 and dopamine D2/D3 receptor occupancy of pridopidine in healthy volunteers and patients with Huntington disease: a [18F] fluspidine and [18F] fallypride PET study

European journal of nuclear medicine and molecular imaging, 2021-04, Vol.48 (4), p.1103-1115

2021

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Origin of the J-M Reef and Lower Banded series, Stillwater Complex, Montana, USA

Precambrian research, 2021-12, Vol.367, p.106457, Article 106457

2021

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Identification of novel substrates for human cytochrome P450 2J2

Drug metabolism and disposition, 2010-02, Vol.38 (2), p.347

2010

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Mapping the 3D extent of the Stillwater Complex, Montana—Implications for potential platinum group element exploration and development

Precambrian research, 2020-09, Vol.348, p.105860, Article 105860

2020

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Reaction phenotyping: advances in the experimental strategies used to characterize the contribution of drug-metabolizing enzymes

Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Relative contributions of cytochrome CYP3A4 versus CYP3A5 for CYP3A-cleared drugs assessed in vitro using a CYP3A4-selective inactivator (CYP3cide)

Contribution of Extrahepatic Aldehyde Oxidase Activity to Human Clearance

Strategies for a comprehensive understanding of metabolism by aldehyde oxidase

Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs

Ontogeny of Human Liver Aldehyde Oxidase: Developmental Changes and Implications for Drug Metabolism

Clearance Prediction of Targeted Covalent Inhibitors by In Vitro-In Vivo Extrapolation of Hepatic and Extrahepatic Clearance Mechanisms

Quantifying and predicting the promiscuity and isoform specificity of small-molecule cytochrome P450 inhibitors

The crystal structure of CYP3A4 in complex with bromocriptine

Characterization of endothelin converting enzyme from intact cells of a permanent human endothelial cell line EA.hy926

CYP and UGT inhibition to assess perpetrator drug-drug interaction potential

Reaction phenotyping for UGT enzymes

Process control with compact NMR

Effect of micro-plastic particles on coral reef foraminifera

The Geochemical and Textural Transition between the Reef Package and its Hanging Wall, Stillwater Complex, Montana, USA

Mineral deposit discovery order and three-part quantitative assessments

Higher HbA1c levels associate with lower hippocampal serotonin transporter availability in non-diabetic adults with obesity

Are CYP3A5 expresser subpopulations at an increased risk for acetaminophen toxicity?

In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase

In situ determination of Os, Ir, and Ru in chromites formed from komatiite, tholeiite and boninite magmas: Implications for chromite control of Os, Ir and Ru during partial melting and crystal fractionation

Sigma-1 and dopamine D2/D3 receptor occupancy of pridopidine in healthy volunteers and patients with Huntington disease: a [18F] fluspidine and [18F] fallypride PET study

Origin of the J-M Reef and Lower Banded series, Stillwater Complex, Montana, USA

Identification of novel substrates for human cytochrome P450 2J2

Mapping the 3D extent of the Stillwater Complex, Montana—Implications for potential platinum group element exploration and development

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