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Isosteric ribavirin analogues: Synthesis and antiviral activities

Bioorganic & medicinal chemistry letters, 2018-01, Vol.28 (1), p.11-14

2018

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Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835

Bioorganic & medicinal chemistry, 2016-11, Vol.24 (21), p.5481-5494

2016

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Novel FFA1 (GPR40) agonists containing spirocyclic periphery: polar azine periphery as a driver of potency

Journal of enzyme inhibition and medicinal chemistry, 2017-01, Vol.32 (1), p.29-36

2017

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Diversity-oriented synthesis of N,N-dimethylamino-substituted azoles employing TBTU

Tetrahedron letters, 2018-07, Vol.59 (28), p.2732-2735

2018

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Spirocyclic amino alcohol building blocks prepared via a Prins-type cyclization in aqueous sulfuric acid

Tetrahedron letters, 2016-07, Vol.57 (30), p.3311-3314

2016

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Exploration of the nitrogen heterocyclic periphery around the core of the advanced FFA1 agonist fasiglifam (TAK‐875)

Archiv der Pharmazie (Weinheim), 2021-04, Vol.354 (4), p.e2000275-n/a

2021

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Novel agonists of free fatty acid receptor 1 (GPR40) based on 3-(1,3,4-thiadiazol-2-yl)propanoic acid scaffold

Journal of enzyme inhibition and medicinal chemistry, 2016-11, Vol.31 (6), p.1404-1410

2016

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Continued SAR exploration of 1,2,4-thiadiazole-containing scaffolds in the design of free fatty acid receptor 1 (GPR40) agonists

European journal of medicinal chemistry, 2017-11, Vol.140, p.229-238

2017

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Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold

Bioorganic & medicinal chemistry, 2016-07, Vol.24 (13), p.2954-2963

2016

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Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH 2 : a novel entry into the 1,2,4-triazine core

RSC advances, 2016, Vol.6 (63), p.57956-57959

2016

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Polar aromatic periphery increases agonist potency of spirocyclic free fatty acid receptor (GPR40) agonists inspired by LY2881835

European journal of medicinal chemistry, 2017-02, Vol.127, p.357-368

2017

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Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase

Bioorganic chemistry, 2018-10, Vol.80, p.655-667

2018

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Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH2: a novel entry into the 1,2,4-triazine coreElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ra12664b

2016-06

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Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH sub(2): a novel entry into the 1,2,4-triazine core

RSC advances, 2016-06, Vol.6 (63), p.57956-57959

2016

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ChemInform Abstract: Spirocyclic Amino Alcohol Building Blocks Prepared via a Prins‐Type Cyclization in Aqueous Sulfuric Acid

ChemInform, 2016-11, Vol.47 (47), p.no-no

2016

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ChemInform Abstract: Zn‐Catalyzed Hydrohydrazination of Propargylamides with BocNHNH2: A Novel Entry into the 1,2,4‐Triazine Core

ChemInform, 2016-10, Vol.47 (45), p.no-no

2016

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ChemInform Abstract: Zn‐Catalyzed Hydrohydrazination of Propargylamides with BocNHNH 2 : A Novel Entry into the 1,2,4‐Triazine Core

ChemInform, 2016-10, Vol.47 (45)

2016

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Isosteric ribavirin analogues: Synthesis and antiviral activities

Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835

Novel FFA1 (GPR40) agonists containing spirocyclic periphery: polar azine periphery as a driver of potency

Diversity-oriented synthesis of N,N-dimethylamino-substituted azoles employing TBTU

Spirocyclic amino alcohol building blocks prepared via a Prins-type cyclization in aqueous sulfuric acid

Exploration of the nitrogen heterocyclic periphery around the core of the advanced FFA1 agonist fasiglifam (TAK‐875)

Novel agonists of free fatty acid receptor 1 (GPR40) based on 3-(1,3,4-thiadiazol-2-yl)propanoic acid scaffold

Continued SAR exploration of 1,2,4-thiadiazole-containing scaffolds in the design of free fatty acid receptor 1 (GPR40) agonists

Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold

Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH 2 : a novel entry into the 1,2,4-triazine core

Polar aromatic periphery increases agonist potency of spirocyclic free fatty acid receptor (GPR40) agonists inspired by LY2881835

Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase

Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH2: a novel entry into the 1,2,4-triazine coreElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ra12664b

Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH sub(2): a novel entry into the 1,2,4-triazine core

ChemInform Abstract: Spirocyclic Amino Alcohol Building Blocks Prepared via a Prins‐Type Cyclization in Aqueous Sulfuric Acid

ChemInform Abstract: Zn‐Catalyzed Hydrohydrazination of Propargylamides with BocNHNH2: A Novel Entry into the 1,2,4‐Triazine Core

ChemInform Abstract: Zn‐Catalyzed Hydrohydrazination of Propargylamides with BocNHNH 2 : A Novel Entry into the 1,2,4‐Triazine Core

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