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Allosteric modulators of NMDA receptors: multiple sites and mechanisms

Current opinion in pharmacology, 2015-02, Vol.20, p.14-23

2015

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Cryo-EM structure of human heptameric Pannexin 1 channel

Cell research, 2020-05, Vol.30 (5), p.446-448

2020

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NMDA receptors as therapeutic targets for depression treatment: Evidence from clinical to basic research

Neuropharmacology, 2023-03, Vol.225, p.109378-109378, Article 109378

2023

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Structural basis of ketamine action on human NMDA receptors

Nature (London), 2021-08, Vol.596 (7871), p.301-305

2021

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Mechanism of NMDA Receptor Inhibition and Activation

Cell, 2016-04, Vol.165 (3), p.704-714

2016

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Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines

The EMBO journal, 2011-08, Vol.30 (15), p.3134-3146

2011

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A pannexin 1 channelopathy causes human oocyte death

Science translational medicine, 2019-03, Vol.11 (485)

2019

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Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors

Cell reports (Cambridge), 2018-12, Vol.25 (13), p.3582-3590.e4

2018

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Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain

Nature structural & molecular biology, 2013-04, Vol.20 (4), p.477-485

2013

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Homozygous variants in PANX1 cause human oocyte death and female infertility

European journal of human genetics : EJHG, 2021-09, Vol.29 (9), p.1396-1404

2021

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Structure and symmetry inform gating principles of ionotropic glutamate receptors

Neuropharmacology, 2017-01, Vol.112 (Pt A), p.11-15

2017

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Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.6081-6086

2014

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Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors

Frontiers in pharmacology, 2022-06, Vol.13, p.888308-888308

2022

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Structural insights into gating mechanism and allosteric regulation of NMDA receptors

Current opinion in neurobiology, 2023-12, Vol.83, p.102806-102806, Article 102806

2023

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Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors

Neuron (Cambridge, Mass.), 2021-08, Vol.109 (15), p.2443-2456.e5

2021

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Expression and Purification of Mammalian NMDA Receptor Protein for Functional Characterization

Methods in molecular biology (Clifton, N.J.), 2024, Vol.2799, p.13

2024

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Prediction of ligand modulation patterns on membrane receptors via lysine reactivity profiling

Chemical communications (Cambridge, England), 2019-04, Vol.55 (30), p.4311-4314

2019

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Controlling NMDA receptor subunit composition using ectopic retention signals

The Journal of neuroscience, 2014-12, Vol.34 (50), p.16630-16636

2014

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Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits

Nature structural & molecular biology, 2023-05, Vol.30 (5), p.629-639

2023

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Author Correction: Structural basis of ketamine action on human NMDA receptors

Nature (London), 2021-10, Vol.598 (7882), p.E3-E3

2021

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Author Correction: Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis

Nature structural & molecular biology, 2024-10

2024

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Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis

Nature structural & molecular biology, 2024-09

2024

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Sevoflurane acts as an antidepressant by suppression of GluN2D‐containing NMDA receptors on interneurons

British journal of pharmacology, 2024-09, Vol.181 (18), p.3483-3502

2024

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Prediction of ligand modulation patterns on membrane receptors via lysine reactivity profilingElectronic supplementary information (ESI) available: Experimental details and supplementary figures and tables. See DOI: 10.1039/c9cc00520j

2019-04

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Novel heterozygous USH1C mutation impacts hair cell mechanotransduction and causes progressive hearing loss

Science bulletin, 2024-01, Vol.69 (2), p.167-172

2024

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Allosteric modulators of NMDA receptors: multiple sites and mechanisms

Cryo-EM structure of human heptameric Pannexin 1 channel

NMDA receptors as therapeutic targets for depression treatment: Evidence from clinical to basic research

Structural basis of ketamine action on human NMDA receptors

Mechanism of NMDA Receptor Inhibition and Activation

Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines

A pannexin 1 channelopathy causes human oocyte death

Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors

Allosteric signaling and dynamics of the clamshell-like NMDA receptor GluN1 N-terminal domain

Homozygous variants in PANX1 cause human oocyte death and female infertility

Structure and symmetry inform gating principles of ionotropic glutamate receptors

Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces

Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors

Structural insights into gating mechanism and allosteric regulation of NMDA receptors

Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors

Expression and Purification of Mammalian NMDA Receptor Protein for Functional Characterization

Prediction of ligand modulation patterns on membrane receptors via lysine reactivity profiling

Controlling NMDA receptor subunit composition using ectopic retention signals

Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits

Author Correction: Structural basis of ketamine action on human NMDA receptors

Author Correction: Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis

Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis

Sevoflurane acts as an antidepressant by suppression of GluN2D‐containing NMDA receptors on interneurons

Prediction of ligand modulation patterns on membrane receptors via lysine reactivity profilingElectronic supplementary information (ESI) available: Experimental details and supplementary figures and tables. See DOI: 10.1039/c9cc00520j

Novel heterozygous USH1C mutation impacts hair cell mechanotransduction and causes progressive hearing loss

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