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Transient Receptor Potential Melastatin 8 (TRPM8) Channels are Involved in Body Temperature Regulation

Molecular pain, 2012-05, Vol.8 (1), p.36-36

2012

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Pharmacologic Characterization of AMG 334, a Potent and Selective Human Monoclonal Antibody against the Calcitonin Gene-Related Peptide Receptor

The Journal of pharmacology and experimental therapeutics, 2016-01, Vol.356 (1), p.223

2016

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Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.3427-3438

2021

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Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats

The Journal of pharmacology and experimental therapeutics, 2008-07, Vol.326 (1), p.218

2008

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AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.474

2005

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Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade

The Journal of pharmacology and experimental therapeutics, 2007-10, Vol.323 (1), p.128

2007

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Antibodies to nerve growth factor reverse established tactile allodynia in rodent models of neuropathic pain without tolerance

The Journal of pharmacology and experimental therapeutics, 2007-07, Vol.322 (1), p.282

2007

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Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel Na V 1.7

The Journal of pharmacology and experimental therapeutics, 2017-07, Vol.362 (1), p.146

2017

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Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles

Journal of medicinal chemistry, 2006-06, Vol.49 (12), p.3719-3742

2006

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PAC1 receptor blockade reduces central nociceptive activity: new approach for primary headache?

Pain (Amsterdam), 2020-07, Vol.161 (7), p.1670-1681

2020

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Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

Journal of medicinal chemistry, 2017-07, Vol.60 (14), p.5990-6017

2017

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The Vanilloid Receptor TRPV1 Is Tonically Activated In Vivo and Involved in Body Temperature Regulation

The Journal of neuroscience, 2007-03, Vol.27 (13), p.3366-3374

2007

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Sulfonamides as Selective Na V 1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

Journal of medicinal chemistry, 2017-07, Vol.60 (14), p.5990-6017

2017

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Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1 H -benzimidazoles

Journal of medicinal chemistry, 2006-06, Vol.49 (12), p.3719-3742

2006

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ATP-Sensitive Potassium Channels Regulate In Vivo Dopamine Release in Rat Striatum

The Japanese Journal of Pharmacology, 1999, Vol.79(1), pp.59-64

1999

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The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets

Oncotarget, 2016-07, Vol.7 (29), p.46750-46767

2016

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Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

The New England journal of medicine, 2018-01, Vol.378 (1), p.11-21

2018

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Dynamic pricing and matching in ride‐hailing platforms

Naval research logistics, 2020-12, Vol.67 (8), p.705-724

2020

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Impacts of COVID-19 on sexual behaviors, HIV prevention and care among men who have sex with men: A comparison of New York City and Metropolitan Atlanta

PloS one, 2023-03, Vol.18 (3), p.e0282503-e0282503

2023

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A Validated Smartphone-Based Assessment of Gait and Gait Variability in Parkinson's Disease

PloS one, 2015-10, Vol.10 (10), p.e0141694-e0141694

2015

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A chemical genetic roadmap to improved tomato flavor

Science (American Association for the Advancement of Science), 2017-01, Vol.355 (6323), p.391-394

2017

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ATP-Sensitive Potassium Channels Regulate In Vivo Dopamine Release in Rat striatum

Japanese Journal of Pharmacology, 1999, Vol.79 (1), p.59-64

1999

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Deletion of Interleukin-6 Attenuates Pressure Overload-Induced Left Ventricular Hypertrophy and Dysfunction

Circulation research, 2016-06, Vol.118 (12), p.1918-1929

2016

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Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

Nature communications, 2021-04, Vol.12 (1), p.2229-2229, Article 2229

2021

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The Many Faces of Robustness: A Critical Analysis of Out-of-Distribution Generalization

2021 IEEE/CVF International Conference on Computer Vision (ICCV), 2021, p.8320-8329

2021

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Transient Receptor Potential Melastatin 8 (TRPM8) Channels are Involved in Body Temperature Regulation

Pharmacologic Characterization of AMG 334, a Potent and Selective Human Monoclonal Antibody against the Calcitonin Gene-Related Peptide Receptor

Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model

Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats

AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties

Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade

Antibodies to nerve growth factor reverse established tactile allodynia in rodent models of neuropathic pain without tolerance

Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel Na V 1.7

Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles

PAC1 receptor blockade reduces central nociceptive activity: new approach for primary headache?

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

The Vanilloid Receptor TRPV1 Is Tonically Activated In Vivo and Involved in Body Temperature Regulation

Sulfonamides as Selective Na V 1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity

Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1 H -benzimidazoles

ATP-Sensitive Potassium Channels Regulate In Vivo Dopamine Release in Rat Striatum

The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets

Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

Dynamic pricing and matching in ride‐hailing platforms

Impacts of COVID-19 on sexual behaviors, HIV prevention and care among men who have sex with men: A comparison of New York City and Metropolitan Atlanta

A Validated Smartphone-Based Assessment of Gait and Gait Variability in Parkinson's Disease

A chemical genetic roadmap to improved tomato flavor

ATP-Sensitive Potassium Channels Regulate In Vivo Dopamine Release in Rat striatum

Deletion of Interleukin-6 Attenuates Pressure Overload-Induced Left Ventricular Hypertrophy and Dysfunction

Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

The Many Faces of Robustness: A Critical Analysis of Out-of-Distribution Generalization

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