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Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

Nature medicine, 2016-04, Vol.22 (4), p.427-432

2016

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Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions

Nature communications, 2020-08, Vol.11 (1), p.3635-3635, Article 3635

2020

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Model-driven mitigation measures for reopening schools during the COVID-19 pandemic

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (39), p.1-10

2021

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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (35), p.15449-15454

2010

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Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores

Genome medicine, 2019-11, Vol.11 (1), p.74-74, Article 74

2019

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Multi-Gene Panel Testing of 23,179 Individuals for Hereditary Cancer Risk Identifies Pathogenic Variant Carriers Missed by Current Genetic Testing Guidelines

The Journal of molecular diagnostics : JMD, 2019-07, Vol.21 (4), p.646-657

2019

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Cancer cells exploit an orphan RNA to drive metastatic progression

Nature medicine, 2018-11, Vol.24 (11), p.1743-1751

2018

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Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1

Cell reports (Cambridge), 2013-03, Vol.3 (3), p.747-758

2013

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A machine learning model to determine the accuracy of variant calls in capture-based next generation sequencing

BMC genomics, 2018-04, Vol.19 (1), p.263-263, Article 263

2018

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IκB Kinase ε Phosphorylates TRAF2 To Promote Mammary Epithelial Cell Transformation

Molecular and Cellular Biology, 2012-12, Vol.32 (23), p.4756-4768

2012

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Whole-genome sequencing as an investigational device for return of hereditary disease risk and pharmacogenomic results as part of the All of Us Research Program

Genome medicine, 2022-03, Vol.14 (1), p.34-34, Article 34

2022

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Machine learning enables new insights into genetic contributions to liver fat accumulation

Cell genomics, 2021-12, Vol.1 (3), p.100066, Article 100066

2021

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Choosing a New Direction on a One-Way Street

Cell, 2020-04, Vol.181 (2), p.212-218

Zhou, Alicia Y.

2020

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IKKε-Mediated Tumorigenesis Requires K63-Linked Polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 Ubiquitin Ligase Complex

Cell reports (Cambridge), 2013-03, Vol.3 (3), p.724-733

2013

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Burden of hereditary cancer susceptibility in unselected patients with pancreatic ductal adenocarcinoma referred for germline screening

Cancer medicine (Malden, MA), 2020-06, Vol.9 (11), p.4004-4013

2020

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A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis

eLife, 2013-10, Vol.2, p.e00822-e00822

2013

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Cascade Genetic Testing of Relatives for Hereditary Cancer Risk: Results of an Online Initiative

JNCI : Journal of the National Cancer Institute, 2019-01, Vol.111 (1), p.95-98

2019

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Digital health-enabled genomics: Opportunities and challenges

American journal of human genetics, 2022-07, Vol.109 (7), p.1190-1198

2022

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Sounding out solutions: using SONAR to connect participants with relevant healthcare resources

Journal of the American Medical Informatics Association : JAMIA, 2024-08

2024

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The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Cell, 2008-05, Vol.133 (4), p.704-715

2008

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PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression

Nature medicine, 2016-11, Vol.22 (11), p.1321-1329

2016

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Prevalence of Inherited Mutations in Breast Cancer Predisposition Genes among Women in Uganda and Cameroon

Cancer epidemiology, biomarkers & prevention, 2020-02, Vol.29 (2), p.359-367

2020

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LEAP: Using machine learning to support variant classification in a clinical setting

Human mutation, 2020-06, Vol.41 (6), p.1079-1090

2020

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Inherited predisposition to breast and ovarian cancer in non-Jewish populations in Israel

Breast cancer research and treatment, 2017-12, Vol.166 (3), p.881-885

2017

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A Randomized Trial of Two Remote Health Care Delivery Models on the Uptake of Genetic Testing and Impact on Patient-Reported Psychological Outcomes in Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, and Testing (GENERATE) Study

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.872-885.e2

2024

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Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions

Model-driven mitigation measures for reopening schools during the COVID-19 pandemic

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores

Multi-Gene Panel Testing of 23,179 Individuals for Hereditary Cancer Risk Identifies Pathogenic Variant Carriers Missed by Current Genetic Testing Guidelines

Cancer cells exploit an orphan RNA to drive metastatic progression

Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1

A machine learning model to determine the accuracy of variant calls in capture-based next generation sequencing

IκB Kinase ε Phosphorylates TRAF2 To Promote Mammary Epithelial Cell Transformation

Whole-genome sequencing as an investigational device for return of hereditary disease risk and pharmacogenomic results as part of the All of Us Research Program

Machine learning enables new insights into genetic contributions to liver fat accumulation

Choosing a New Direction on a One-Way Street

IKKε-Mediated Tumorigenesis Requires K63-Linked Polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 Ubiquitin Ligase Complex

Burden of hereditary cancer susceptibility in unselected patients with pancreatic ductal adenocarcinoma referred for germline screening

A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis

Cascade Genetic Testing of Relatives for Hereditary Cancer Risk: Results of an Online Initiative

Digital health-enabled genomics: Opportunities and challenges

Sounding out solutions: using SONAR to connect participants with relevant healthcare resources

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression

Prevalence of Inherited Mutations in Breast Cancer Predisposition Genes among Women in Uganda and Cameroon

LEAP: Using machine learning to support variant classification in a clinical setting

Inherited predisposition to breast and ovarian cancer in non-Jewish populations in Israel

A Randomized Trial of Two Remote Health Care Delivery Models on the Uptake of Genetic Testing and Impact on Patient-Reported Psychological Outcomes in Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, and Testing (GENERATE) Study

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