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Focal adhesion kinase is activated by microtubule‐depolymerizing agents and regulates membrane blebbing in human endothelial cells

Journal of cellular and molecular medicine, 2020-07, Vol.24 (13), p.7228-7238

2020

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A CD13‐targeting peptide integrated protein inhibits human liver cancer growth by killing cancer stem cells and suppressing angiogenesis

Molecular carcinogenesis, 2017-05, Vol.56 (5), p.1395-1404

2017

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Pingyangmycin enhances the antitumor efficacy of anti-PD-1 therapy associated with tumor-infiltrating CD8+ T cell augmentation

Cancer chemotherapy and pharmacology, 2021-03, Vol.87 (3), p.425-436

2021

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An EGFR‐targeting antibody–drug conjugate LR004‐VC‐MMAE: potential in esophageal squamous cell carcinoma and other malignancies

Molecular oncology, 2019-02, Vol.13 (2), p.246-263

2019

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EGFR-targeting, β-defensin-tailored fusion protein exhibits high therapeutic efficacy against EGFR-expressed human carcinoma via mitochondria-mediated apoptosis

Acta pharmacologica Sinica, 2018-11, Vol.39 (11), p.1777-1786

2018

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The ionophore antibiotic gramicidin A inhibits pancreatic cancer stem cells associated with CD47 down-regulation

Cancer cell international, 2019-05, Vol.19 (1), p.145-145, Article 145

2019

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Dexamethasone enhances the antitumor efficacy of Gemcitabine by glucocorticoid receptor signaling

Cancer biology & therapy, 2020-04, Vol.21 (4), p.332-343

2020

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Excellent effects and possible mechanisms of action of a new antibody-drug conjugate against EGFR-positive triple-negative breast cancer

Military medical research, 2021-12, Vol.8 (1), p.63-63, Article 63

2021

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Enediyne anticancer antibiotic lidamycin: chemistry, biology and pharmacology

Anti-cancer agents in medicinal chemistry, 2008-02, Vol.8 (2), p.123

2008

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An EGFR/HER2-Bispecific and enediyne-energized fusion protein shows high efficacy against esophageal cancer

PloS one, 2014-03, Vol.9 (3), p.e92986

2014

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Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer

Journal of pharmaceutical analysis, 2022-04, Vol.12 (2), p.232-242

2022

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The development of human serum albumin-based drugs and relevant fusion proteins for cancer therapy

International journal of biological macromolecules, 2021-09, Vol.187, p.24-34

2021

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A multifunctional drug combination shows highly potent therapeutic efficacy against human cancer xenografts in athymic mice

PloS one, 2014-12, Vol.9 (12), p.e115790

2014

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A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers

NPJ precision oncology, 2024-04, Vol.8 (1), p.94-94, Article 94

2024

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Intensive fibrosarcoma-binding capability of the reconstituted analog and its antitumor activity

Drug delivery, 2018-01, Vol.25 (1), p.102-111

2018

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Preparation and Evaluation of a CD13/APN-Targeting and Hydrolase-Resistant Conjugate that Comprises Pingyangmycin and NGR Motif-Integrated Apoprotein

Journal of pharmaceutical sciences, 2014-04, Vol.103 (4), p.1204-1213

2014

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IMB5476, a novel microtubule inhibitor, induces mitotic catastrophe and overcomes multidrug resistance in tumors

European journal of pharmacology, 2022-03, Vol.919, p.174802-174802, Article 174802

2022

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HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin

Cancer chemotherapy and pharmacology, 2005-08, Vol.56 (2), p.212-220

2005

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hIMB1636-MMAE, a Novel TROP2-Targeting Antibody-Drug Conjugate Exerting Potent Antitumor Efficacy in Pancreatic Cancer

Journal of medicinal chemistry, 2023-11, Vol.66 (21), p.14700-14715

2023

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Elucidating the development, characterization, and antitumor potential of a novel humanized antibody against Trop2

International journal of biological macromolecules, 2023-12, Vol.253, p.127105-127105, Article 127105

2023

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Targeting Telomere Dynamics as an Effective Approach for the Development of Cancer Therapeutics

International journal of nanomedicine, 2024-01, Vol.19, p.3805-3825

2024

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DBDx-based drug combinations show highly potent therapeutic efficacy against human pancreatic cancer xenografts in athymic mice

Cancer biology & therapy, 2020-08, Vol.21 (8), p.749-757

2020

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The Recombinant and Reconstituted Novel Albumin–Lidamycin Conjugate Shows Lasting Tumor Imaging and Intensively Enhanced Therapeutic Efficacy

Bioconjugate chemistry, 2018-09, Vol.29 (9), p.3104-3112

2018

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Enediyne lidamycin induces apoptosis in human multiple myeloma cells through activation of p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase

International journal of hematology, 2009-07, Vol.90 (1), p.44-51

2009

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Recombinant EGFR/MMP-2 bi-targeted fusion protein markedly binding to non-small-cell lung carcinoma and exerting potent therapeutic efficacy

Pharmacological research, 2017-12, Vol.126, p.66-76

2017

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Focal adhesion kinase is activated by microtubule‐depolymerizing agents and regulates membrane blebbing in human endothelial cells

A CD13‐targeting peptide integrated protein inhibits human liver cancer growth by killing cancer stem cells and suppressing angiogenesis

Pingyangmycin enhances the antitumor efficacy of anti-PD-1 therapy associated with tumor-infiltrating CD8+ T cell augmentation

An EGFR‐targeting antibody–drug conjugate LR004‐VC‐MMAE: potential in esophageal squamous cell carcinoma and other malignancies

EGFR-targeting, β-defensin-tailored fusion protein exhibits high therapeutic efficacy against EGFR-expressed human carcinoma via mitochondria-mediated apoptosis

The ionophore antibiotic gramicidin A inhibits pancreatic cancer stem cells associated with CD47 down-regulation

Dexamethasone enhances the antitumor efficacy of Gemcitabine by glucocorticoid receptor signaling

Excellent effects and possible mechanisms of action of a new antibody-drug conjugate against EGFR-positive triple-negative breast cancer

Enediyne anticancer antibiotic lidamycin: chemistry, biology and pharmacology

An EGFR/HER2-Bispecific and enediyne-energized fusion protein shows high efficacy against esophageal cancer

Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer

The development of human serum albumin-based drugs and relevant fusion proteins for cancer therapy

A multifunctional drug combination shows highly potent therapeutic efficacy against human cancer xenografts in athymic mice

A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers

Intensive fibrosarcoma-binding capability of the reconstituted analog and its antitumor activity

Preparation and Evaluation of a CD13/APN-Targeting and Hydrolase-Resistant Conjugate that Comprises Pingyangmycin and NGR Motif-Integrated Apoprotein

IMB5476, a novel microtubule inhibitor, induces mitotic catastrophe and overcomes multidrug resistance in tumors

HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin

hIMB1636-MMAE, a Novel TROP2-Targeting Antibody-Drug Conjugate Exerting Potent Antitumor Efficacy in Pancreatic Cancer

Elucidating the development, characterization, and antitumor potential of a novel humanized antibody against Trop2

Targeting Telomere Dynamics as an Effective Approach for the Development of Cancer Therapeutics

DBDx-based drug combinations show highly potent therapeutic efficacy against human pancreatic cancer xenografts in athymic mice

The Recombinant and Reconstituted Novel Albumin–Lidamycin Conjugate Shows Lasting Tumor Imaging and Intensively Enhanced Therapeutic Efficacy

Enediyne lidamycin induces apoptosis in human multiple myeloma cells through activation of p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase

Recombinant EGFR/MMP-2 bi-targeted fusion protein markedly binding to non-small-cell lung carcinoma and exerting potent therapeutic efficacy

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