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Altered intestinal microbial flora and impaired epithelial barrier structure and function in CKD: the nature, mechanisms, consequences and potential treatment

Nephrology, dialysis, transplantation, 2016-05, Vol.31 (5), p.737-746

2016

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Traditional uses, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus (Pers.) Fries: A review

Journal of ethnopharmacology, 2013-08, Vol.149 (1), p.35-48

Zhao, Ying-Yong

2013

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Novel inhibitors of the cellular renin‐angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β‐catenin pathway against renal fibrosis

British journal of pharmacology, 2018-07, Vol.175 (13), p.2689-2708

2018

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Gut microbiota-derived tryptophan metabolism mediates renal fibrosis by aryl hydrocarbon receptor signaling activation

Cellular and molecular life sciences : CMLS, 2021-02, Vol.78 (3), p.909-922

2021

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Small molecule inhibitors of epithelial‐mesenchymal transition for the treatment of cancer and fibrosis

Medicinal research reviews, 2020-01, Vol.40 (1), p.54-78

2020

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Architectures and accuracy of artificial neural network for disease classification from omics data

BMC genomics, 2019-03, Vol.20 (1), p.167-167, Article 167

2019

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Metabolomics highlights pharmacological bioactivity and biochemical mechanism of traditional Chinese medicine

Chemico-biological interactions, 2017-08, Vol.273, p.133-141

2017

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Microbiome–metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease

Cellular and molecular life sciences : CMLS, 2019-12, Vol.76 (24), p.4961-4978

2019

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Microbiome-metabolome reveals the contribution of gut-kidney axis on kidney disease

Journal of translational medicine, 2019-01, Vol.17 (1), p.5-5, Article 5

2019

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Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan‐produced indole metabolites

British journal of pharmacology, 2024-01, Vol.181 (1), p.162-179

2024

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Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

Experimental and Molecular Medicine, 2019, 51(0), , pp.1-18

2019

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Identification of endogenous 1‐aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation

British journal of pharmacology, 2020-08, Vol.177 (15), p.3415-3435

2020

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Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan

Nature communications, 2019-04, Vol.10 (1), p.1476-1476, Article 1476

2019

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1‐Hydroxypyrene mediates renal fibrosis through aryl hydrocarbon receptor signalling pathway

British journal of pharmacology, 2022-01, Vol.179 (1), p.103-124

2022

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Small molecules from natural products targeting the Wnt/β-catenin pathway as a therapeutic strategy

Biomedicine & pharmacotherapy, 2019-09, Vol.117, p.108990-108990, Article 108990

2019

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Metabolomic Signatures of Chronic Kidney Disease of Diverse Etiologies in the Rats and Humans

Journal of proteome research, 2016-10, Vol.15 (10), p.3802-3812

2016

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TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis

Frontiers in pharmacology, 2022-03, Vol.13, p.860588-860588

2022

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Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma

Journal of translational medicine, 2019-09, Vol.17 (1), p.302-302, Article 302

2019

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Ultra performance liquid chromatography-based metabonomic study of therapeutic effect of the surface layer of Poria cocos on adenine-induced chronic kidney disease provides new insight into anti-fibrosis mechanism

PloS one, 2013-03, Vol.8 (3), p.e59617

2013

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Metabolomics analysis reveals the association between lipid abnormalities and oxidative stress, inflammation, fibrosis and Nrf2 dysfunction in aristolochic acid-induced nephropathy

Scientific reports, 2015-08, Vol.5 (1), p.12936-12936, Article 12936

2015

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Ultra-performance liquid chromatography–mass spectrometry as a sensitive and powerful technology in lipidomic applications

Chemico-biological interactions, 2014-09, Vol.220, p.181-192

2014

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The Matrix Metalloproteinase‐13 Inhibitor Poricoic Acid ZI Ameliorates Renal Fibrosis by Mitigating Epithelial‐Mesenchymal Transition

Molecular nutrition & food research, 2019-07, Vol.63 (13), p.e1900132-n/a

2019

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Combined Clinical Phenotype and Lipidomic Analysis Reveals the Impact of Chronic Kidney Disease on Lipid Metabolism

Journal of proteome research, 2017-04, Vol.16 (4), p.1566-1578

2017

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Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis

Frontiers in pharmacology, 2021-08, Vol.12, p.719880-719880

2021

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An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure

Scientific reports, 2016-02, Vol.6 (1), p.22151-22151, Article 22151

2016

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Altered intestinal microbial flora and impaired epithelial barrier structure and function in CKD: the nature, mechanisms, consequences and potential treatment

Traditional uses, phytochemistry, pharmacology, pharmacokinetics and quality control of Polyporus umbellatus (Pers.) Fries: A review

Novel inhibitors of the cellular renin‐angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β‐catenin pathway against renal fibrosis

Gut microbiota-derived tryptophan metabolism mediates renal fibrosis by aryl hydrocarbon receptor signaling activation

Small molecule inhibitors of epithelial‐mesenchymal transition for the treatment of cancer and fibrosis

Architectures and accuracy of artificial neural network for disease classification from omics data

Metabolomics highlights pharmacological bioactivity and biochemical mechanism of traditional Chinese medicine

Microbiome–metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease

Microbiome-metabolome reveals the contribution of gut-kidney axis on kidney disease

Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan‐produced indole metabolites

Unilateral ureteral obstruction causes gut microbial dysbiosis and metabolome disorders contributing to tubulointerstitial fibrosis

Identification of endogenous 1‐aminopyrene as a novel mediator of progressive chronic kidney disease via aryl hydrocarbon receptor activation

Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan

1‐Hydroxypyrene mediates renal fibrosis through aryl hydrocarbon receptor signalling pathway

Small molecules from natural products targeting the Wnt/β-catenin pathway as a therapeutic strategy

Metabolomic Signatures of Chronic Kidney Disease of Diverse Etiologies in the Rats and Humans

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis

Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma

Ultra performance liquid chromatography-based metabonomic study of therapeutic effect of the surface layer of Poria cocos on adenine-induced chronic kidney disease provides new insight into anti-fibrosis mechanism

Metabolomics analysis reveals the association between lipid abnormalities and oxidative stress, inflammation, fibrosis and Nrf2 dysfunction in aristolochic acid-induced nephropathy

Ultra-performance liquid chromatography–mass spectrometry as a sensitive and powerful technology in lipidomic applications

The Matrix Metalloproteinase‐13 Inhibitor Poricoic Acid ZI Ameliorates Renal Fibrosis by Mitigating Epithelial‐Mesenchymal Transition

Combined Clinical Phenotype and Lipidomic Analysis Reveals the Impact of Chronic Kidney Disease on Lipid Metabolism

Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis

An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure

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