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Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition

Clinical cancer research, 2017-05, Vol.23 (9), p.2255-2266

2017

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Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9

Protein & cell, 2017-09, Vol.8 (9), p.634-643

2017

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Increasing the safety and efficacy of chimeric antigen receptor T cell therapy

Protein & cell, 2017-08, Vol.8 (8), p.573-589

2017

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Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18

Cell reports (Cambridge), 2017-09, Vol.20 (13), p.3025-3033

2017

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Tim-4 in Health and Disease: Friend or Foe?

Frontiers in immunology, 2020-04, Vol.11, p.537

2020

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Adoptive Immunotherapy for Cancer or Viruses

Annual review of immunology, 2014-01, Vol.32 (1), p.189-225

2014

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Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies

Cancer immunology research, 2014-02, Vol.2 (2), p.112-120

2014

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Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor

Cancer research (Chicago, Ill.), 2010-11, Vol.70 (22), p.9053-9061

2010

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Treatment of advanced leukemia in mice with mRNA engineered T cells

Human gene therapy, 2011-12, Vol.22 (12), p.1575-1586

2011

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Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability

Cancer research (Chicago, Ill.), 2006-09, Vol.66 (17), p.8878-8886

2006

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iGUIDE: an improved pipeline for analyzing CRISPR cleavage specificity

Genome Biology, 2019-01, Vol.20 (1), p.14-14, Article 14

2019

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Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice

The Journal of clinical investigation, 2010-11, Vol.120 (11), p.3953-3968

2010

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Construction and preclinical evaluation of an anti-CD19 chimeric antigen receptor

Journal of immunotherapy, 2009-09, Vol.32 (7), p.689-702

2009

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Novel T cells with improved in vivo anti-tumor activity generated by RNA electroporation

Protein & cell, 2017-07, Vol.8 (7), p.514-526

2017

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CRISPR/Cas9 genome editing: Fueling the revolution in cancer immunotherapy

Current research in translational medicine, 2018-05, Vol.66 (2), p.39-42

2018

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TCR affinity and specificity requirements for human regulatory T-cell function

Blood, 2012-04, Vol.119 (15), p.3420-3430

2012

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A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8), p.3027-3033

2010

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Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes

Human gene therapy, 2009-06, Vol.20 (6), p.630-640

2009

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A prospective, randomized study on hepatotoxicity of anastrozole compared with tamoxifen in women with breast cancer

Cancer science, 2014-09, Vol.105 (9), p.1182-1188

2014

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Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via notch signaling

Cancer research (Chicago, Ill.), 2007-03, Vol.67 (6), p.2425-2429

2007

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Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

Cancer Immunology, Immunotherapy, 2009-03, Vol.58 (3), p.383-394

2009

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A versatile system for rapid multiplex genome-edited CAR T cell generation

Oncotarget, 2017-03, Vol.8 (10), p.17002-17011

2017

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Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication

Molecular therapy, 2018-07, Vol.26 (7), p.1855-1866

2018

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A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors

Cancer research (Chicago, Ill.), 2016-03, Vol.76 (6), p.1578-1590

2016

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Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition

Advancing chimeric antigen receptor T cell therapy with CRISPR/Cas9

Increasing the safety and efficacy of chimeric antigen receptor T cell therapy

Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18

Tim-4 in Health and Disease: Friend or Foe?

Adoptive Immunotherapy for Cancer or Viruses

Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid Malignancies

Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor

Treatment of advanced leukemia in mice with mRNA engineered T cells

Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability

iGUIDE: an improved pipeline for analyzing CRISPR cleavage specificity

Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice

Construction and preclinical evaluation of an anti-CD19 chimeric antigen receptor

Novel T cells with improved in vivo anti-tumor activity generated by RNA electroporation

CRISPR/Cas9 genome editing: Fueling the revolution in cancer immunotherapy

TCR affinity and specificity requirements for human regulatory T-cell function

A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas

Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes

A prospective, randomized study on hepatotoxicity of anastrozole compared with tamoxifen in women with breast cancer

Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via notch signaling

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

A versatile system for rapid multiplex genome-edited CAR T cell generation

Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication

PSMA-targeting TGFβ-insensitive armored CAR T cells in metastatic castration-resistant prostate cancer: a phase 1 trial

A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors

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