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Determination of critical quality attributes for monoclonal antibodies using quality by design principles

Biologicals, 2016-09, Vol.44 (5), p.291-305

2016

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Characterization and Stability Study of Polysorbate 20 in Therapeutic Monoclonal Antibody Formulation by Multidimensional Ultrahigh-Performance Liquid Chromatography–Charged Aerosol Detection–Mass Spectrometry

Analytical chemistry (Washington), 2014-05, Vol.86 (10), p.5150-5157

2014

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Isolation and characterization of therapeutic antibody charge variants using cation exchange displacement chromatography

Journal of Chromatography A, 2011-08, Vol.1218 (31), p.5079-5086

2011

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Native Hydrophobic Interaction Chromatography Hyphenated to Mass Spectrometry for Characterization of Monoclonal Antibody Minor Variants

Analytical chemistry (Washington), 2019-12, Vol.91 (24), p.15360-15364

2019

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Effect of Individual Fc Methionine Oxidation on FcRn Binding: Met252 Oxidation Impairs FcRn Binding More Profoundly than Met428 Oxidation

Journal of pharmaceutical sciences, 2015-02, Vol.104 (2), p.368-377

2015

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Development of a rapid RP-UHPLC–MS method for analysis of modifications in therapeutic monoclonal antibodies

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-10, Vol.1032, p.172-181

2016

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Glycation of antibodies: Modification, methods and potential effects on biological functions

mAbs, 2017-05, Vol.9 (4), p.586-594

2017

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Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation

mAbs, 2021-01, Vol.13 (1), p.1893427-1893427

2021

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High resolution separation of recombinant monoclonal antibodies by size-exclusion ultra-high performance liquid chromatography (SE-UHPLC)

Journal of pharmaceutical and biomedical analysis, 2015-05, Vol.109, p.52-61

2015

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Pure Pleasure

The Massachusetts review, 2021-07, Vol.62 (2), p.332-332

Zhang, Taylor

2021

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Identification of a single base-pair mutation of TAA (Stop codon) → GAA (Glu) that causes light chain extension in a CHO cell derived IgG1

mAbs, 2012-11, Vol.4 (6), p.694-700

2012

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Developing patient-centric specifications for autologous chimeric antigen receptor T cell therapies

Current opinion in biomedical engineering, 2021-12, Vol.20, p.100328, Article 100328

2021

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Quantitation of polysorbate 20 in protein solutions using mixed-mode chromatography and evaporative light scattering detection

Journal of Chromatography A, 2008-12, Vol.1215 (1), p.156-160

2008

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Mixed-mode and reversed-phase liquid chromatography–tandem mass spectrometry methodologies to study composition and base hydrolysis of polysorbate 20 and 80

Journal of Chromatography A, 2011-04, Vol.1218 (15), p.2138-2145

2011

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Identification and Characterization of Buried Unpaired Cysteines in a Recombinant Monoclonal IgG1 Antibody

Analytical chemistry (Washington), 2012-08, Vol.84 (16), p.7112-7123

2012

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High resolution reversed phase analysis of recombinant monoclonal antibodies by ultra-high pressure liquid chromatography column coupling

Journal of pharmaceutical and biomedical analysis, 2013-09, Vol.83, p.273-278

2013

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Structure-Based Correlation of Light-Induced Histidine Reactivity in A Model Protein

Analytical chemistry (Washington), 2017-07, Vol.89 (13), p.7225-7231

2017

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Reversed-phase chromatography with large pore superficially porous particles for high throughput immunoglobulin G 2 disulfide isoform separation

Journal of Chromatography A, 2017-12, Vol.1526, p.104-111

2017

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Reversed-phase chromatography with large pore superficially porous particles for high throughput immunoglobulin G2 disulfide isoform separation

Journal of Chromatography A, 2017-12, Vol.1526, p.104-111

2017

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Reactive impurities in large and small molecule pharmaceutical excipients – A review

TrAC, Trends in analytical chemistry (Regular ed.), 2018-04, Vol.101, p.34-42

2018

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Promoting remyelination for the treatment of multiple sclerosis： opportunities and challenges

Neuroscience bulletin, 2013-04, Vol.29 (2), p.144-154

2013

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Rapid Identification of Low Level Glycation Sites in Recombinant Antibodies by Isotopic Labeling with 13 C 6 -Reducing Sugars

Analytical chemistry (Washington), 2012-03, Vol.84 (5), p.2313-2320

2012

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Rapid Identification of Low Level Glycation Sites in Recombinant Antibodies by Isotopic Labeling with ^sup 13^C^sub 6^-Reducing Sugars

Analytical chemistry (Washington), 2012-03, Vol.84 (5), p.2313

2012

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Asparagine Deamidation Dependence on Buffer Type, pH, and Temperature

Journal of pharmaceutical sciences, 2013-06, Vol.102 (6), p.1712-1723

2013

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Rapid Identification of Low Level Glycation Sites in Recombinant Antibodies by Isotopic Labeling with 13C6-Reducing Sugars

Analytical chemistry (Washington), 2012-03, Vol.84 (5), p.2313-2320

2012

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Determination of critical quality attributes for monoclonal antibodies using quality by design principles

Characterization and Stability Study of Polysorbate 20 in Therapeutic Monoclonal Antibody Formulation by Multidimensional Ultrahigh-Performance Liquid Chromatography–Charged Aerosol Detection–Mass Spectrometry

Isolation and characterization of therapeutic antibody charge variants using cation exchange displacement chromatography

Native Hydrophobic Interaction Chromatography Hyphenated to Mass Spectrometry for Characterization of Monoclonal Antibody Minor Variants

Effect of Individual Fc Methionine Oxidation on FcRn Binding: Met252 Oxidation Impairs FcRn Binding More Profoundly than Met428 Oxidation

Development of a rapid RP-UHPLC–MS method for analysis of modifications in therapeutic monoclonal antibodies

Glycation of antibodies: Modification, methods and potential effects on biological functions

Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation

High resolution separation of recombinant monoclonal antibodies by size-exclusion ultra-high performance liquid chromatography (SE-UHPLC)

Pure Pleasure

Identification of a single base-pair mutation of TAA (Stop codon) → GAA (Glu) that causes light chain extension in a CHO cell derived IgG1

Developing patient-centric specifications for autologous chimeric antigen receptor T cell therapies

Quantitation of polysorbate 20 in protein solutions using mixed-mode chromatography and evaporative light scattering detection

Mixed-mode and reversed-phase liquid chromatography–tandem mass spectrometry methodologies to study composition and base hydrolysis of polysorbate 20 and 80

Identification and Characterization of Buried Unpaired Cysteines in a Recombinant Monoclonal IgG1 Antibody

High resolution reversed phase analysis of recombinant monoclonal antibodies by ultra-high pressure liquid chromatography column coupling

Structure-Based Correlation of Light-Induced Histidine Reactivity in A Model Protein

Reversed-phase chromatography with large pore superficially porous particles for high throughput immunoglobulin G 2 disulfide isoform separation

Reversed-phase chromatography with large pore superficially porous particles for high throughput immunoglobulin G2 disulfide isoform separation

Reactive impurities in large and small molecule pharmaceutical excipients – A review

Promoting remyelination for the treatment of multiple sclerosis： opportunities and challenges

Rapid Identification of Low Level Glycation Sites in Recombinant Antibodies by Isotopic Labeling with 13 C 6 -Reducing Sugars

Rapid Identification of Low Level Glycation Sites in Recombinant Antibodies by Isotopic Labeling with ^sup 13^C^sub 6^-Reducing Sugars

Asparagine Deamidation Dependence on Buffer Type, pH, and Temperature

Rapid Identification of Low Level Glycation Sites in Recombinant Antibodies by Isotopic Labeling with 13C6-Reducing Sugars

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