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The Serum- and Glucocorticoid-inducible Kinases SGK1 and SGK3 Regulate hERG Channel Expression via Ubiquitin Ligase Nedd4-2 and GTPase Rab11

The Journal of biological chemistry, 2013-05, Vol.288 (21), p.15075-15084

2013

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Regulation of the Human Ether-a-go-go-related Gene (hERG) Channel by Rab4 Protein through Neural Precursor Cell-expressed Developmentally Down-regulated Protein 4-2 (Nedd4-2)

The Journal of biological chemistry, 2013-07, Vol.288 (30), p.21876-21886

2013

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Blockade of the Human Ether A-Go-Go-Related Gene (hERG) Potassium Channel by Fentanyl

Molecular pharmacology, 2019-04, Vol.95 (4), p.386-397

2019

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Isolation and characterization of IKr in cardiac myocytes by Cs+ permeation

American journal of physiology. Heart and circulatory physiology, 2006-03, Vol.290 (3), p.H1038

Zhang, Shetuan

2006

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Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips)

Biochemical journal, 2015-11, Vol.472 (1), p.71-82

2015

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The ion channel basis of pharmacological effects of amiodarone on myocardial electrophysiological properties, a comprehensive review

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116513, Article 116513

2024

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Effect of Preoperative Obstructive Sleep Apnea on the Frequency of Atrial Fibrillation After Coronary Artery Bypass Grafting

The American journal of cardiology, 2014-03, Vol.113 (6), p.919-923

2014

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Glycosylation stabilizes hERG channels on the plasma membrane by decreasing proteolytic susceptibility

The FASEB journal, 2018-04, Vol.32 (4), p.1933-1943

2018

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Extracellular K+ Is a Prerequisite for the Function and Plasma Membrane Stability of HERG Channels

Circulation research, 2010-04, Vol.106 (6), p.1072-1082

2010

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Cell Surface Expression of Human Ether-a-go-go-related Gene (hERG) Channels Is Regulated by Caveolin-3 Protein via the Ubiquitin Ligase Nedd4-2

The Journal of biological chemistry, 2012-09, Vol.287 (40), p.33132-33141

2012

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Reduced hemodynamic load aids low-dose resveratrol in reversing cardiovascular defects in hypertensive rats

Hypertension research, 2013-10, Vol.36 (10), p.866-872

2013

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Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.911

2007

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Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway

European journal of pharmacology, 2011-10, Vol.668 (1-2), p.217-224

2011

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Muscarinic receptor activation increases hERG channel expression through phosphorylation of ubiquitin ligase Nedd4-2

Molecular pharmacology, 2014-06, Vol.85 (6), p.877-886

2014

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Febrile temperature facilitates hERG/IKr degradation through an altered K+ dependence

Heart rhythm, 2016-10, Vol.13 (10), p.2004-2011

2016

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Involvement of Caveolin in Low K+-induced Endocytic Degradation of Cell-surface Human Ether-a-go-go-related Gene (hERG) Channels

The Journal of biological chemistry, 2010-08, Vol.285 (35), p.27259-27264

2010

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Interaction between the Cardiac Rapidly (IKr) and Slowly (IKs) Activating Delayed Rectifier Potassium Channels Revealed by Low K+-induced hERG Endocytic Degradation

The Journal of biological chemistry, 2011-10, Vol.286 (40), p.34664-34674

2011

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Extracellular K+ Is a Prerequisite for the Function and Stability of HERG Channels in the Plasma Membrane

Journal of arrhythmia, 2011, Vol.27 (Supplement), p.SS2_2

Zhang, Shetuan

2011

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The Role of Monoubiquitination in Endocytic Degradation of Human Ether-a-go-go-related Gene (hERG) Channels under Low K+ Conditions

The Journal of biological chemistry, 2011-02, Vol.286 (8), p.6751-6759

2011

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Na+ permeation and block of hERG potassium channels

The Journal of general physiology, 2006-07, Vol.128 (1), p.55-71

2006

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COVID-19 Drugs Chloroquine and Hydroxychloroquine, but Not Azithromycin and Remdesivir, Block hERG Potassium Channels

The Journal of pharmacology and experimental therapeutics, 2021-05, Vol.377 (2), p.265-272

2021

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Mechanism of Block and Identification of the Verapamil Binding Domain to HERG Potassium Channels

Circulation research, 1999-05, Vol.84 (9), p.989-998

1999

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Abstract 1718: Differential effects of remdesivir and lumacaftor on homo- and heterotetrameric hERG channels

The Journal of biological chemistry, 2023, Vol.299 (3), p.104056, Article 104056

2023

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Abstract 1663: Extracellular protease calpain cleaves Kv1.5 at the S1-S2 linker and increases the channel current

The Journal of biological chemistry, 2023, Vol.299 (3), p.104048, Article 104048

2023

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Differential Regulation of HERG Current and Expression by Activation of Protein Kinase C

Biophysical journal, 2018-02, Vol.114 (3), p.131a-131a

2018

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The Serum- and Glucocorticoid-inducible Kinases SGK1 and SGK3 Regulate hERG Channel Expression via Ubiquitin Ligase Nedd4-2 and GTPase Rab11

Regulation of the Human Ether-a-go-go-related Gene (hERG) Channel by Rab4 Protein through Neural Precursor Cell-expressed Developmentally Down-regulated Protein 4-2 (Nedd4-2)

Blockade of the Human Ether A-Go-Go-Related Gene (hERG) Potassium Channel by Fentanyl

Isolation and characterization of IKr in cardiac myocytes by Cs+ permeation

Regulation of the human ether-a-go-go-related gene (hERG) potassium channel by Nedd4 family interacting proteins (Ndfips)

The ion channel basis of pharmacological effects of amiodarone on myocardial electrophysiological properties, a comprehensive review

Effect of Preoperative Obstructive Sleep Apnea on the Frequency of Atrial Fibrillation After Coronary Artery Bypass Grafting

Glycosylation stabilizes hERG channels on the plasma membrane by decreasing proteolytic susceptibility

Extracellular K+ Is a Prerequisite for the Function and Plasma Membrane Stability of HERG Channels

Cell Surface Expression of Human Ether-a-go-go-related Gene (hERG) Channels Is Regulated by Caveolin-3 Protein via the Ubiquitin Ligase Nedd4-2

Reduced hemodynamic load aids low-dose resveratrol in reversing cardiovascular defects in hypertensive rats

Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes

Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway

Muscarinic receptor activation increases hERG channel expression through phosphorylation of ubiquitin ligase Nedd4-2

Febrile temperature facilitates hERG/IKr degradation through an altered K+ dependence

Involvement of Caveolin in Low K+-induced Endocytic Degradation of Cell-surface Human Ether-a-go-go-related Gene (hERG) Channels

Interaction between the Cardiac Rapidly (IKr) and Slowly (IKs) Activating Delayed Rectifier Potassium Channels Revealed by Low K+-induced hERG Endocytic Degradation

Extracellular K+ Is a Prerequisite for the Function and Stability of HERG Channels in the Plasma Membrane

The Role of Monoubiquitination in Endocytic Degradation of Human Ether-a-go-go-related Gene (hERG) Channels under Low K+ Conditions

Na+ permeation and block of hERG potassium channels

COVID-19 Drugs Chloroquine and Hydroxychloroquine, but Not Azithromycin and Remdesivir, Block hERG Potassium Channels

Mechanism of Block and Identification of the Verapamil Binding Domain to HERG Potassium Channels

Abstract 1718: Differential effects of remdesivir and lumacaftor on homo- and heterotetrameric hERG channels

Abstract 1663: Extracellular protease calpain cleaves Kv1.5 at the S1-S2 linker and increases the channel current

Differential Regulation of HERG Current and Expression by Activation of Protein Kinase C

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