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Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

Nature communications, 2020-04, Vol.11 (1), p.1996-14, Article 1996

2020

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Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity

Nature communications, 2021-11, Vol.12 (1), p.6896-6896, Article 6896

2021

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Optimization of X-axis servo drive performance using PSO fuzzy control technique for double-axis dicing saw

Scientific reports, 2023-11, Vol.13 (1), p.20719-20719, Article 20719

2023

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Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells

Nature communications, 2021-02, Vol.12 (1), p.1281-1281, Article 1281

2021

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DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

Journal of hematology and oncology, 2020-07, Vol.13 (1), p.95-13, Article 95

2020

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Molecular Mechanisms of Hepatocarcinogenesis Following Sustained Virological Response in Patients with Chronic Hepatitis C Virus Infection

Viruses, 2018-09, Vol.10 (10), p.531

2018

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Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL

Nature communications, 2024-03, Vol.15 (1), p.2743-2743

2024

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Laboratory-scale Method to Assess the Durability of Rendering Mortar and Concrete Adhesion Systems

Journal of Advanced Concrete Technology, 2020/09/24, Vol.18(9), pp.521-531

2020

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TNF Receptor: Fc Fusion Protein Downregulates RANKL/OPG Ratio by Inhibiting CXCL16/CXCR6 in Active Ankylosing Spondylitis

Current pharmaceutical biotechnology, 2021-01, Vol.22 (2), p.305

2021

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Formulation development of anti-rheumatoid gel of Saraca asoca (Roxb.) De Wilde hydroalcoholic extract containing eucalyptus oil and peppermint oil as penetration enhancer

Brazilian Journal of Pharmaceutical Sciences, 2022-01, Vol.58

2022

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The burden of Hepatitis B virus infection in Kenya: A systematic review and meta-analysis

Frontiers in public health, 2023-01, Vol.11, p.986020-986020

2023

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The psychological impact of the COVID-19 outbreak among the fever patients in the lockdown zone

BMC Psychology, 2023-03, Vol.11 (1), p.69-69, Article 69

2023

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PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer

Cells (Basel, Switzerland), 2024-03, Vol.13 (6), p.528

2024

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Axial plane single-molecule super-resolution microscopy of whole cells

Biomedical optics express, 2020-01, Vol.11 (1), p.461-479

2020

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AhR agonist tapinarof ameliorates lupus autoimmunity by suppressing Tfh cell differentiation via regulation of the JAK2‐STAT3 signaling pathway

Immunity, Inflammation and Disease, 2023-06, Vol.11 (6), p.e903-n/a

2023

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Concise Synthesis of (S)‑δ-CEHC, a Metabolite of Vitamin E

ACS omega, 2021-02, Vol.6 (6), p.4355-4361

2021

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PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

Exploration of targeted anti-tumor therapy, 2020, Vol.1 (4), p.259-272

2020

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Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

Cell death discovery, 2023-01, Vol.9 (1), p.1-10, Article 1

2023

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BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers

Journal of hematology and oncology, 2022-03, Vol.15 (1), p.23-23, Article 23

2022

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In Situ Synthetic ZIF-8/Carbon Aerogel Composites as Solid-Phase Microextraction Coating for the Detection of Phthalic Acid Esters in Water Samples

Gels, 2022-09, Vol.8 (10), p.610

2022

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Targeting BCL-XL in fibrolamellar hepatocellular carcinoma

JCI insight, 2022-09, Vol.7 (17)

2022

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Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib

Therapeutic advances in medical oncology, 2020, Vol.12, p.1758835920922051

2020

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A Stochastic Approximation-Langevinized Ensemble Kalman Filter Algorithm for State Space Models with Unknown Parameters

Journal of computational and graphical statistics, 2023, Vol.32 (2), p.448-469

2023

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Utilizing PROTAC technology to address the on-target platelet toxicity associated with inhibition of BCL-X

Chemical communications (Cambridge, England), 2019-12, Vol.55 (98), p.14765-14768

2019

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Utilizing PROTAC technology to address the on-target platelet toxicity associated with inhibition of BCL-X L

Chemical communications (Cambridge, England), 2019-12, Vol.55 (98), p.14765-14768

2019

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Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity

Optimization of X-axis servo drive performance using PSO fuzzy control technique for double-axis dicing saw

Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells

DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

Molecular Mechanisms of Hepatocarcinogenesis Following Sustained Virological Response in Patients with Chronic Hepatitis C Virus Infection

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL

Laboratory-scale Method to Assess the Durability of Rendering Mortar and Concrete Adhesion Systems

TNF Receptor: Fc Fusion Protein Downregulates RANKL/OPG Ratio by Inhibiting CXCL16/CXCR6 in Active Ankylosing Spondylitis

Formulation development of anti-rheumatoid gel of Saraca asoca (Roxb.) De Wilde hydroalcoholic extract containing eucalyptus oil and peppermint oil as penetration enhancer

The burden of Hepatitis B virus infection in Kenya: A systematic review and meta-analysis

The psychological impact of the COVID-19 outbreak among the fever patients in the lockdown zone

PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer

Axial plane single-molecule super-resolution microscopy of whole cells

AhR agonist tapinarof ameliorates lupus autoimmunity by suppressing Tfh cell differentiation via regulation of the JAK2‐STAT3 signaling pathway

Concise Synthesis of (S)‑δ-CEHC, a Metabolite of Vitamin E

PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers

In Situ Synthetic ZIF-8/Carbon Aerogel Composites as Solid-Phase Microextraction Coating for the Detection of Phthalic Acid Esters in Water Samples

Targeting BCL-XL in fibrolamellar hepatocellular carcinoma

Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib

A Stochastic Approximation-Langevinized Ensemble Kalman Filter Algorithm for State Space Models with Unknown Parameters

Utilizing PROTAC technology to address the on-target platelet toxicity associated with inhibition of BCL-X

Utilizing PROTAC technology to address the on-target platelet toxicity associated with inhibition of BCL-X L

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