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The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies

Cancer research (Chicago, Ill.), 2015-09, Vol.75 (18), p.3865-3878

2015

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Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor

Journal of medicinal chemistry, 2016-02, Vol.59 (4), p.1440-1454

2016

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Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

Molecular therapy, 2014-08, Vol.22 (8), p.1494-1503

2014

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Insulin-like Growth Factor-1 Receptor Transactivation Modulates the Inflammatory and Proliferative Responses of Neurotensin in Human Colonic Epithelial Cells

The Journal of biological chemistry, 2011-02, Vol.286 (8), p.6092-6099

2011

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Substance P Mediates Antiapoptotic Responses in Human Colonocytes by Akt activation

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (6), p.2013-2018

2007

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Substance P Stimulates Cyclooxygenase-2 and Prostaglandin E2 Expression through JAK-STAT Activation in Human Colonic Epithelial Cells

The Journal of immunology (1950), 2006-04, Vol.176 (8), p.5050-5059

2006

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Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery

Epigenetics & chromatin, 2015-09, Vol.8 (1), p.37-37, Article 37

2015

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Control of Cell Growth and Survival by Enzymes of the Fatty Acid Synthesis Pathway in HCT-116 Colon Cancer Cells

Clinical cancer research, 2008-09, Vol.14 (18), p.5735-5742

2008

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Neurotensin stimulates expression of early growth response gene‐1 and EGF receptor through MAP kinase activation in human colonic epithelial cells

International journal of cancer, 2007-04, Vol.120 (8), p.1652-1656

2007

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Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2

Biochemical journal, 2015-03, Vol.466 (2), p.337-346

2015

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C-Met Inhibitor MK-8003 Radiosensitizes c-Met–Expressing Non–Small-Cell Lung Cancer Cells With Radiation-Induced c-Met–Expression

Journal of thoracic oncology, 2012-08, Vol.7 (8), p.1211-1217

2012

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Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-κB pathway in human colonic epithelial cells

Journal of cellular biochemistry, 2006-04, Vol.97 (6), p.1317-1327

2006

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Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2A

Biochemical journal, 2015-03, Vol.466 (2), p.337-346

2015

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Abstract 3528: The SMARCA2/4 catalytic activity, but not the bromodomain, is a drug target in SWI/SNF mutant cancers

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.3528-3528

2015

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Abstract 1099: MiR-200c overexpression radiosensitizes lung cancer cells

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1099-1099

2012

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Substance P-Stimulated Interleukin-8 Expression in Human Colonic Epithelial Cells Involves Protein Kinase Cδ Activation

The Journal of pharmacology and experimental therapeutics, 2005-09, Vol.314 (3), p.1393-1400

2005

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Metalloproteinase-dependent transforming growth factor-alpha release mediates neurotensin-stimulated MAP kinase activation in human colonic epithelial cells

The Journal of biological chemistry, 2004-10, Vol.279 (42), p.43547-43554

2004

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Neurotensin stimulates interleukin-8 expression through modulation of I kappa B alpha phosphorylation and p65 transcriptional activity: involvement of protein kinase C alpha

Molecular pharmacology, 2005-06, Vol.67 (6), p.2025-2031

2005

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Substance P Stimulates Cyclooxygenase-2 and Prostaglandin E2 Expression through JAK-STAT Activation in Human Colonic Epithelial Cells1

The Journal of immunology (1950), 2006-04, Vol.176 (8), p.5050-5059

2006

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Substance P Stimulates Cyclooxygenase-2 and Prostaglandin E sub(2) Expression through JAK-STAT Activation in Human Colonic Epithelial Cells

Journal of Immunology, 2006-04, Vol.176 (8), p.5050-5059

2006

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Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-kappaB pathway in human colonic epithelial cells

Journal of cellular biochemistry, 2006-04, Vol.97 (6), p.1317

2006

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Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves protein kinase Cdelta activation

The Journal of pharmacology and experimental therapeutics, 2005-09, Vol.314 (3), p.1393

2005

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Ghrelin stimulates interleukin-8 gene expression through protein kinase C- mediated NF-[kappa]B pathway in human colonic epithelial cells

Journal of cellular biochemistry, 2006-01, Vol.97 (6), p.1317-1327

2006

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Neurotensin Stimulates Interleukin-8 Expression through Modulation of IÎºBÎ± Phosphorylation and p65 Transcriptional Activity: Involvement of Protein Kinase CÎ

Molecular pharmacology, 2005-06, Vol.67 (6), p.2025

2005

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Metalloproteinase-dependent Transforming Growth Factor-Î± Release Mediates Neurotensin-stimulated MAP Kinase Activation in Human Colonic Epithelial Cells

The Journal of biological chemistry, 2004-10, Vol.279 (42), p.43547

2004

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The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies

Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor

Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

Insulin-like Growth Factor-1 Receptor Transactivation Modulates the Inflammatory and Proliferative Responses of Neurotensin in Human Colonic Epithelial Cells

Substance P Mediates Antiapoptotic Responses in Human Colonocytes by Akt activation

Substance P Stimulates Cyclooxygenase-2 and Prostaglandin E2 Expression through JAK-STAT Activation in Human Colonic Epithelial Cells

Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery

Control of Cell Growth and Survival by Enzymes of the Fatty Acid Synthesis Pathway in HCT-116 Colon Cancer Cells

Neurotensin stimulates expression of early growth response gene‐1 and EGF receptor through MAP kinase activation in human colonic epithelial cells

Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2

C-Met Inhibitor MK-8003 Radiosensitizes c-Met–Expressing Non–Small-Cell Lung Cancer Cells With Radiation-Induced c-Met–Expression

Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-κB pathway in human colonic epithelial cells

Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2A

Abstract 3528: The SMARCA2/4 catalytic activity, but not the bromodomain, is a drug target in SWI/SNF mutant cancers

Abstract 1099: MiR-200c overexpression radiosensitizes lung cancer cells

Substance P-Stimulated Interleukin-8 Expression in Human Colonic Epithelial Cells Involves Protein Kinase Cδ Activation

Metalloproteinase-dependent transforming growth factor-alpha release mediates neurotensin-stimulated MAP kinase activation in human colonic epithelial cells

Neurotensin stimulates interleukin-8 expression through modulation of I kappa B alpha phosphorylation and p65 transcriptional activity: involvement of protein kinase C alpha

Substance P Stimulates Cyclooxygenase-2 and Prostaglandin E2 Expression through JAK-STAT Activation in Human Colonic Epithelial Cells1

Substance P Stimulates Cyclooxygenase-2 and Prostaglandin E sub(2) Expression through JAK-STAT Activation in Human Colonic Epithelial Cells

Ghrelin stimulates interleukin-8 gene expression through protein kinase C-mediated NF-kappaB pathway in human colonic epithelial cells

Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves protein kinase Cdelta activation

Ghrelin stimulates interleukin-8 gene expression through protein kinase C- mediated NF-[kappa]B pathway in human colonic epithelial cells

Neurotensin Stimulates Interleukin-8 Expression through Modulation of IÎºBÎ± Phosphorylation and p65 Transcriptional Activity: Involvement of Protein Kinase CÎ

Metalloproteinase-dependent Transforming Growth Factor-Î± Release Mediates Neurotensin-stimulated MAP Kinase Activation in Human Colonic Epithelial Cells

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