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The opposite impact of Janus kinase inhibitor Ruxolitinib on the function of bone marrow mesenchymal stem cells and immune cells in acute GVHD recipients

Blood science, 2023-10, Vol.5 (4), p.277-279

Zeng, Defu

2023

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IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

The Journal of experimental medicine, 2009-07, Vol.206 (7), p.1457-1464

2009

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Dual-responsive mesoporous poly-N-isopropylacrylamide-hydroxyapatite composite microspheres for controlled anticancer drug delivery

Journal of sol-gel science and technology, 2021-03, Vol.97 (3), p.600-609

2021

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IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice

Nature communications, 2021-02, Vol.12 (1), p.805-805, Article 805

2021

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Steroid-Refractory Gut Graft-Versus-Host Disease: What We Have Learned From Basic Immunology and Experimental Mouse Model

Frontiers in immunology, 2022-02, Vol.13, p.844271-844271

2022

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Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80

Frontiers in immunology, 2018-12, Vol.9, p.3061-3061

2018

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Growth factors and medium hyperglycemia induce Sox9⁺ ductal cell differentiation into β cells in mice with reversal of diabetes

Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (3), p.650-655

2016

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Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

Nature communications, 2017-10, Vol.8 (1), p.978-17, Article 978

2017

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Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice

Blood, 2016-05, Vol.127 (18), p.2249-2260

2016

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Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

Blood, 2009-10, Vol.114 (14), p.3101-3112

2009

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Murine Models Provide New Insights Into Pathogenesis of Chronic Graft- Versus -Host Disease in Humans

Frontiers in immunology, 2021-09, Vol.12, p.700857-700857

2021

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Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity

Frontiers in immunology, 2022-05, Vol.13, p.907673-907673

2022

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Mouse models usher in precision medicine

Blood, 2020-06, Vol.135 (26), p.2331-2333

Zeng, Defu

2020

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Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity

The Journal of clinical investigation, 2023-08, Vol.133 (15)

2023

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microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function

PLoS biology, 2022-02, Vol.20 (2), p.e3001552-e3001552

2022

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Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease

Blood, 2008-09, Vol.112 (5), p.2101-2110

2008

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Bridge between type 1 diabetes in mouse and man

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (41), p.10821-10823

Zeng, Defu

2017

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In vivo–activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease

Blood, 2008-09, Vol.112 (5), p.2129-2138

2008

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Newly found arsons ignite the fire of gut GVHD

The Journal of clinical investigation, 2018-03, Vol.128 (3), p.897-899

Zeng, Defu

2018

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HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (12), p.4796-4801

2008

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Induction of Mixed Chimerism Depletes Pre-existing and De Novo-Developed Autoreactive B Cells in Autoimmune NOD Mice

Diabetes (New York, N.Y.), 2014-06, Vol.63 (6), p.2051-2062

2014

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MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (52), p.15994-15999

2015

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Induction of Mixed Chimerism With MHC-Mismatched but Not Matched Bone Marrow Transplants Results in Thymic Deletion of Host-Type Autoreactive T-Cells in NOD Mice

Diabetes (New York, N.Y.), 2011-02, Vol.60 (2), p.555-564

2011

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Regulators help new immigrants settle down?

Blood, 2014-05, Vol.123 (18), p.2754-2756

Zeng, Defu

2014

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442.5: Cellular and molecular mechanisms that tolerize donor and host reactive T cells in MHC-mismatched mixed chimeras

Transplantation, 2024-09, Vol.108 (9S)

2024

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The opposite impact of Janus kinase inhibitor Ruxolitinib on the function of bone marrow mesenchymal stem cells and immune cells in acute GVHD recipients

IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

Dual-responsive mesoporous poly-N-isopropylacrylamide-hydroxyapatite composite microspheres for controlled anticancer drug delivery

IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice

Steroid-Refractory Gut Graft-Versus-Host Disease: What We Have Learned From Basic Immunology and Experimental Mouse Model

Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80

Growth factors and medium hyperglycemia induce Sox9⁺ ductal cell differentiation into β cells in mice with reversal of diabetes

Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease

Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

Murine Models Provide New Insights Into Pathogenesis of Chronic Graft- Versus -Host Disease in Humans

Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity

Mouse models usher in precision medicine

Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity

microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function

Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease

Bridge between type 1 diabetes in mouse and man

In vivo–activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease

Newly found arsons ignite the fire of gut GVHD

HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen

Induction of Mixed Chimerism Depletes Pre-existing and De Novo-Developed Autoreactive B Cells in Autoimmune NOD Mice

MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice

Induction of Mixed Chimerism With MHC-Mismatched but Not Matched Bone Marrow Transplants Results in Thymic Deletion of Host-Type Autoreactive T-Cells in NOD Mice

Regulators help new immigrants settle down?

442.5: Cellular and molecular mechanisms that tolerize donor and host reactive T cells in MHC-mismatched mixed chimeras

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