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Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia

Cancer cell, 2016-01, Vol.29 (1), p.32-48

2016

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Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

Cell stem cell, 2011-06, Vol.8 (6), p.649-662

2011

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Therapeutic Opportunities of Targeting Canonical and Noncanonical PcG TrxG Functions in Acute Myeloid Leukemia

Annual review of genomics and human genetics, 2021-08, Vol.22 (1), p.103-125

2021

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A Knockout Combo: Eradicating AML Stem Cells with TKI plus SIRT1 Inhibition

Cell stem cell, 2014-10, Vol.15 (4), p.395-397

2014

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Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular Immortalization

Molecular and Cellular Biology, 2004-01, Vol.24 (2), p.617-628

2004

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HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Cancer cell, 2019-12, Vol.36 (6), p.645-659.e8

2019

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Collaboration between PcG Proteins and MLL Fusions in Leukemogenesis: An Emerging Paradigm

Cancer cell, 2011-11, Vol.20 (5), p.551-553

2011

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Linking MLL Leukemia with Integrin Signaling

Cancer cell, 2013-07, Vol.24 (1), p.5-7

2013

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β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells

Cancer cell, 2010-12, Vol.18 (6), p.606-618

2010

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HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia

Molecular cell, 2022-02, Vol.82 (4), p.833-851.e11

2022

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Transforming activity of AML1-ETO is independent of CBFβ and ETO interaction but requires formation of homo-oligomeric complexes

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2853-2858

2009

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Combinatorial Tethering: A Novel Mode to Recruit Non-canonical PRC1 for Normal and Malignant GC B Cell Development

Cancer cell, 2016-08, Vol.30 (2), p.185-187

2016

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SnapShot: Acute Myeloid Leukemia

Cancer cell, 2012-11, Vol.22 (5), p.698-698.e1

2012

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MLL-AF4, a double-edged sword for iPSC respecification into HSPCs

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (9), p.1964-1966

2018

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Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia

Science translational medicine, 2021-02, Vol.13 (582)

2021

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Transcriptional memory of cells of origin overrides β‐catenin requirement of MLL cancer stem cells

The EMBO journal, 2017-11, Vol.36 (21), p.3139-3155

2017

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Reconstruction of Human AML Using Functionally and Immunophenotypically Defined Human Haematopoietic Stem and Progenitor Cells as Targeted Populations

Bio-protocol, 2021-12, Vol.11 (24), p.e4262-e4262

2021

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The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin

Oncogene, 2005-08, Vol.24 (35), p.5525-5532

2005

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Direct Physical and Functional Interaction of the NuA4 Complex Components Yaf9p and Swc4p

Eukaryotic Cell, 2004-08, Vol.3 (4), p.976-983

2004

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Forced homo-oligomerization of RARα leads to transformation of primary hematopoietic cells

Cancer cell, 2006-02, Vol.9 (2), p.95-108

2006

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The role of CBFβ in AML1-ETO's activity

Blood, 2010-04, Vol.115 (15), p.3176-3177

2010

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Reconstructing the Disease Model and Epigenetic Networks for MLL-AF4 Leukemia

Cancer cell, 2008-11, Vol.14 (5), p.345-347

2008

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Retroviral/Lentiviral transduction and transformation assay

Methods in molecular biology (Clifton, N.J.), 2009, Vol.538, p.207

2009

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Leukemic transformation by the APL fusion protein PRKAR1A-RARα critically depends on recruitment of RXRα

Blood, 2010-01, Vol.115 (3), p.643-652

2010

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Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation

The EMBO journal, 2013-04, Vol.32 (7), p.982-995

2013

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Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia

Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

Therapeutic Opportunities of Targeting Canonical and Noncanonical PcG TrxG Functions in Acute Myeloid Leukemia

A Knockout Combo: Eradicating AML Stem Cells with TKI plus SIRT1 Inhibition

Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular Immortalization

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Collaboration between PcG Proteins and MLL Fusions in Leukemogenesis: An Emerging Paradigm

Linking MLL Leukemia with Integrin Signaling

β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells

HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia

Transforming activity of AML1-ETO is independent of CBFβ and ETO interaction but requires formation of homo-oligomeric complexes

Combinatorial Tethering: A Novel Mode to Recruit Non-canonical PRC1 for Normal and Malignant GC B Cell Development

SnapShot: Acute Myeloid Leukemia

MLL-AF4, a double-edged sword for iPSC respecification into HSPCs

Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia

Transcriptional memory of cells of origin overrides β‐catenin requirement of MLL cancer stem cells

Reconstruction of Human AML Using Functionally and Immunophenotypically Defined Human Haematopoietic Stem and Progenitor Cells as Targeted Populations

The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin

Direct Physical and Functional Interaction of the NuA4 Complex Components Yaf9p and Swc4p

Forced homo-oligomerization of RARα leads to transformation of primary hematopoietic cells

The role of CBFβ in AML1-ETO's activity

Reconstructing the Disease Model and Epigenetic Networks for MLL-AF4 Leukemia

Retroviral/Lentiviral transduction and transformation assay

Leukemic transformation by the APL fusion protein PRKAR1A-RARα critically depends on recruitment of RXRα

Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation

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