UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Bile Acids Activated Receptors Regulate Innate Immunity

Frontiers in immunology, 2018-08, Vol.9, p.1853-1853

2018

Volltextzugriff (PDF)

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

The Journal of immunology (1950), 2017-07, Vol.199 (2), p.718-733

2017

Volltextzugriff (PDF)

Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders

Current opinion in pharmacology, 2020-08, Vol.53, p.45-54

2020

Volltextzugriff (PDF)

Theonella : A Treasure Trove of Structurally Unique and Biologically Active Sterols

Marine drugs, 2023-05, Vol.21 (5), p.291

2023

Volltextzugriff (PDF)

Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1

PloS one, 2015-11, Vol.10 (11), p.e0141082-e0141082

2015

Volltextzugriff (PDF)

Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH

Scientific reports, 2023-01, Vol.13 (1), p.1602-1602, Article 1602

2023

Volltextzugriff (PDF)

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation

PloS one, 2013-01, Vol.8 (1), p.e54472

2013

Volltextzugriff (PDF)

Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

Frontiers in chemistry, 2020-10, Vol.8, p.572885-572885

2020

Volltextzugriff (PDF)

Development of dual GPBAR1 agonist and RORγt inverse agonist for the treatment of inflammatory bowel diseases

Pharmacological research, 2024-10, Vol.208, p.107403, Article 107403

2024

Volltextzugriff (PDF)

The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy

The FASEB journal, 2021-01, Vol.35 (1), p.e21271-n/a

2021

Volltextzugriff (PDF)

Design, Synthesis, and Biological Evaluation of Potent Dual Agonists of Nuclear and Membrane Bile Acid Receptors

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.937-954

2014

Volltextzugriff (PDF)

Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists

Molecules (Basel, Switzerland), 2023-03, Vol.28 (6), p.2840

2023

Volltextzugriff (PDF)

Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1092

2022

Volltextzugriff (PDF)

Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling

PloS one, 2015-07, Vol.10 (7), p.e0129866-e0129866

2015

Volltextzugriff (PDF)

Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential

Frontiers in oncology, 2021-05, Vol.11, p.663771-663771

2021

Volltextzugriff (PDF)

Development of FXR, PXR and CAR agonists and antagonists for treatment of liver disorders

Current topics in medicinal chemistry, 2012-03, Vol.12 (6), p.605-624

2012

Volltextzugriff (PDF)

Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis

Frontiers in oncology, 2022-06, Vol.12, p.939969-939969

2022

Volltextzugriff (PDF)

Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists

Scientific reports, 2016-01, Vol.6 (1), p.19008-19008, Article 19008

2016

Volltextzugriff (PDF)

Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma

Frontiers in oncology, 2023-03, Vol.13, p.1140730-1140730

2023

Volltextzugriff (PDF)

Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

Nutrients, 2019-05, Vol.11 (5), p.1132

2019

Volltextzugriff (PDF)

Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

ACS medicinal chemistry letters, 2019-04, Vol.10 (4), p.504-510

2019

Volltextzugriff (PDF)

Binding Mechanism of the Farnesoid X Receptor Marine Antagonist Suvanine Reveals a Strategy To Forestall Drug Modulation on Nuclear Receptors. Design, Synthesis, and Biological Evaluation of Novel Ligands

Journal of medicinal chemistry, 2013-06, Vol.56 (11), p.4701-4717

2013

Volltextzugriff (PDF)

Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism

Scientific reports, 2015-11, Vol.5 (1), p.16605-16605, Article 16605

2015

Volltextzugriff (PDF)

Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition

The FASEB journal, 2012-07, Vol.26 (7), p.3021-3031

2012

Volltextzugriff (PDF)

Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis

PloS one, 2012-01, Vol.7 (1), p.e30443-e30443

2012

Volltextzugriff (PDF)

1 – 25 von 243

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(225)
Mit Volltextzugriff
(231)

Publikationsform

Artikel
(242)
Buchkapitel
(1)

Sprache

Englisch
(241)
Italienisch
(1)

Erscheinungsjahr

n.n

Thema

Science & Technology
(162)
Life Sciences & Biomedicine
(97)
Humans
(78)
Animals
(75)
Pharmacology & Pharmacy
(59)
Chemistry
(57)
Physical Sciences
(56)
Chemistry, Organic
(43)
Chemistry, Medicinal
(42)
Mice
(30)
Hep G2 Cells
(29)
Bile Acids
(28)
Receptors, Cytoplasmic And Nuclear - Metabolism
(25)
Biochemistry & Molecular Biology
(24)
Ligands
(23)
Receptors, G-Protein-Coupled - Metabolism
(21)
Marine
(20)
Bile Acids And Salts - Metabolism
(18)
Biological And Medical Sciences
(18)
Structure-Activity Relationship
(18)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

Gastroenterology
(31)
Tetrahedron
(20)
Cheminform
(14)
Journal Of Medicinal Chemistry
(13)
European Journal Of Organic Chemistry
(11)
Scientific Reports
(10)
Journal Of Natural Products
(9)
Marine Drugs
(8)
Biochemical Pharmacology
(7)
Plos One
(6)

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(3)

Menü

Weitere Dienste

Einstellungen

Bile Acids Activated Receptors Regulate Innate Immunity

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis

Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders

Theonella : A Treasure Trove of Structurally Unique and Biologically Active Sterols

Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1

Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation

Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain

Development of dual GPBAR1 agonist and RORγt inverse agonist for the treatment of inflammatory bowel diseases

The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy

Design, Synthesis, and Biological Evaluation of Potent Dual Agonists of Nuclear and Membrane Bile Acid Receptors

Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists

Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction

Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling

Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential

Development of FXR, PXR and CAR agonists and antagonists for treatment of liver disorders

Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis

Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists

Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma

Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation

Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

Binding Mechanism of the Farnesoid X Receptor Marine Antagonist Suvanine Reveals a Strategy To Forestall Drug Modulation on Nuclear Receptors. Design, Synthesis, and Biological Evaluation of Novel Ligands

Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism

Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition

Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis

Suchergebnisse filtern