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A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis

Nature communications, 2022-02, Vol.13 (1), p.649-14, Article 649

2022

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Regulation of autoimmune and anti‐tumour T‐cell responses by PTPN22

Immunology, 2018-07, Vol.154 (3), p.377-382

2018

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Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

Nature immunology, 2003-07, Vol.4 (7), p.680-686

2003

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Translation factor eIF5a is essential for IFNγ production and cell cycle regulation in primary CD8 + T lymphocytes

Nature communications, 2022-12, Vol.13 (1), p.7796-7796, Article 7796

2022

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The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals

Nature immunology, 2014-09, Vol.15 (9), p.875-883

2014

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Resistance to TGFβ suppression and improved anti-tumor responses in CD8 + T cells lacking PTPN22

Nature communications, 2017-11, Vol.8 (1), p.1343-10, Article 1343

2017

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Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2

Frontiers in immunology, 2018-11, Vol.9, p.2595-2595

2018

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Modulation of TCR Signaling by Tyrosine Phosphatases: From Autoimmunity to Immunotherapy

Frontiers in cell and developmental biology, 2020-12, Vol.8, p.608747-608747

2020

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The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens

Scientific reports, 2018-08, Vol.8 (1), p.12692-11, Article 12692

2018

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Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice

The Journal of immunology (1950), 2016-07, Vol.197 (2), p.429-440

2016

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miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

PLoS biology, 2019-03, Vol.17 (3), p.e2006716-e2006716

2019

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Protein tyrosine phosphatase PTPN22 regulates IL‐1β dependent Th17 responses by modulating dectin‐1 signaling in mice

European journal of immunology, 2018-02, Vol.48 (2), p.306-315

2018

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Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells

The Journal of immunology (1950), 2017-08, Vol.199 (3), p.874-884

2017

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Centrosome docking at the immunological synapse is controlled by Lck signaling

The Journal of cell biology, 2011-02, Vol.192 (4), p.663-674

2011

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PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion

Frontiers in immunology, 2020-01, Vol.11, p.52-52

2020

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Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion

Journal for immunotherapy of cancer, 2023-12, Vol.11 (12), p.e007614

2023

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Lck Regulates the Threshold of Activation in Primary T Cells, While both Lck and Fyn Contribute to the Magnitude of the Extracellular Signal-Related Kinase Response

Molecular and Cellular Biology, 2006-11, Vol.26 (22), p.8655-8665

2006

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Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells

PloS one, 2012-04, Vol.7 (4), p.e35466

2012

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Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells

PloS one, 2017-10, Vol.12 (10), p.e0186625-e0186625

2017

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T cell receptor signalling networks: branched, diversified and bounded

Nature reviews. Immunology, 2013-04, Vol.13 (4), p.257-269

2013

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Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival

Ecology and evolution, 2016-12, Vol.6 (24), p.8695-8705

2016

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Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses

Frontiers in immunology, 2020-03, Vol.11, p.376

2020

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Differential Requirement for Lck during Primary and Memory CD8⁺ T Cell Responses

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (44), p.16388-16393

2006

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Fyn Regulates the Duration of TCR Engagement Needed for Commitment to Effector Function

Journal of Immunology, 2007-10, Vol.179 (7), p.4635-4644

2007

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How does the mammalian target of rapamycin (mTOR) influence CD8 T-cell differentiation?

Cell cycle (Georgetown, Tex.), 2010-08, Vol.9 (15), p.3024-3029

2010

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A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis

Regulation of autoimmune and anti‐tumour T‐cell responses by PTPN22

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

Translation factor eIF5a is essential for IFNγ production and cell cycle regulation in primary CD8 + T lymphocytes

The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals

Resistance to TGFβ suppression and improved anti-tumor responses in CD8 + T cells lacking PTPN22

Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2

Modulation of TCR Signaling by Tyrosine Phosphatases: From Autoimmunity to Immunotherapy

The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens

Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice

miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

Protein tyrosine phosphatase PTPN22 regulates IL‐1β dependent Th17 responses by modulating dectin‐1 signaling in mice

Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells

Centrosome docking at the immunological synapse is controlled by Lck signaling

PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion

Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion

Lck Regulates the Threshold of Activation in Primary T Cells, While both Lck and Fyn Contribute to the Magnitude of the Extracellular Signal-Related Kinase Response

Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells

Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells

T cell receptor signalling networks: branched, diversified and bounded

Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival

Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses

Differential Requirement for Lck during Primary and Memory CD8⁺ T Cell Responses

Fyn Regulates the Duration of TCR Engagement Needed for Commitment to Effector Function

How does the mammalian target of rapamycin (mTOR) influence CD8 T-cell differentiation?

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