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Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus

Antimicrobial Agents and Chemotherapy, 1997-07, Vol.41 (7), p.1444-1448

1997

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BMS-200475, a novel carbocyclic 2′-deoxyguanosine analog with potent and selective anti-hepatitis B virus activity in vitro

Bioorganic & medicinal chemistry letters, 1997-01, Vol.7 (2), p.127-132

1997

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Accounts in drug discovery: case studies in medicinal chemistry.

1, 2010

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Na-K-ATPase alpha-isoform expression in heart and vascular endothelia: cellular and developmental regulation

American Journal of Physiology: Cell Physiology, 1996-01, Vol.270 (1), p.C361-C371

1996

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Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor

Journal of Virology, 1995-04, Vol.69 (4), p.2148-2152

1995

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Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics

Journal of medicinal chemistry, 2005-01, Vol.48 (1), p.171-179

2005

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The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase

Proceedings of the National Academy of Sciences - PNAS, 1992-01, Vol.89 (1), p.99-103

1992

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Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2233-2239

2004

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Na, K-ATPase isoform gene expression in normal and hypertrophied dog heart

Basic research in cardiology, 1996-05, Vol.91 (3), p.256-266

1996

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Metabolic Studies on BMS-200475, a New Antiviral Compound Active against Hepatitis B Virus

Antimicrobial Agents and Chemotherapy, 1999-01, Vol.43 (1), p.190-193

1999

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Synthesis of SQ-32,829, a new nucleoside antiviral agent

Tetrahedron letters, 1989, Vol.30 (50), p.6955-6958

1989

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Lactic acidosis: effect of treatment on intracellular pH and energetics in living rat heart

American journal of physiology. Heart and circulatory physiology, 1992-05, Vol.262 (5), p.H1572-H1578

1992

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Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease

Antimicrobial Agents and Chemotherapy, 1995-02, Vol.39 (2), p.374-379

1995

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Estimation of heart mitochondrial creatine kinase flux using magnetization transfer NMR spectroscopy

American journal of physiology. Heart and circulatory physiology, 1992-04, Vol.262 (4), p.H1022-H1028

1992

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Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1435-1440

2005

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Titanium-mediated methylene-transfer reactions. Direct conversion of esters into vinyl ethers

Journal of the American Chemical Society, 1980-04, Vol.102 (9), p.3270-3272

1980

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Synthesis of SQ-33,054, a novel cyclobutane nucleoside with potent antiviral activity

Tetrahedron letters, 1989, Vol.30 (47), p.6453-6456

1989

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Sodium kinetics of Na,K-ATPase alpha isoforms in intact transfected HeLa cells

The Journal of general physiology, 1997-08, Vol.110 (2), p.201-213

1997

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Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2227-2231

2004

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Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors

Bioorganic & medicinal chemistry letters, 2002-11, Vol.12 (21), p.3229-3233

2002

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Synthesis of potent and highly selective inhibitors of human tryptase

Bioorganic & medicinal chemistry letters, 2002-11, Vol.12 (21), p.3235-3238

2002

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Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors

Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (24), p.5453-5458

2005

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Aminodiol HIV protease inhibitors. 2. 1,1-Dimethyl-2-hydroxyethyl carbamate derivatives with enhanced potency

Bioorganic & medicinal chemistry letters, 1995-03, Vol.5 (5), p.459-464

1995

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A new detail in a complex case

Annals of internal medicine, 1983-05, Vol.98 (5 Pt 1), p.674

Zahler, R

1983

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Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells

Oncogene, 1995-05, Vol.10 (9), p.1763-1779

1995

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Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus

BMS-200475, a novel carbocyclic 2′-deoxyguanosine analog with potent and selective anti-hepatitis B virus activity in vitro

Accounts in drug discovery: case studies in medicinal chemistry.

Na-K-ATPase alpha-isoform expression in heart and vascular endothelia: cellular and developmental regulation

Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor

Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics

The cardiac conduction system in the rat expresses the alpha 2 and alpha 3 isoforms of the Na+,K(+)-ATPase

Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors

Na, K-ATPase isoform gene expression in normal and hypertrophied dog heart

Metabolic Studies on BMS-200475, a New Antiviral Compound Active against Hepatitis B Virus

Synthesis of SQ-32,829, a new nucleoside antiviral agent

Lactic acidosis: effect of treatment on intracellular pH and energetics in living rat heart

Antiviral properties of aminodiol inhibitors against human immunodeficiency virus and protease

Estimation of heart mitochondrial creatine kinase flux using magnetization transfer NMR spectroscopy

Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase

Titanium-mediated methylene-transfer reactions. Direct conversion of esters into vinyl ethers

Synthesis of SQ-33,054, a novel cyclobutane nucleoside with potent antiviral activity

Sodium kinetics of Na,K-ATPase alpha isoforms in intact transfected HeLa cells

Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase

Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors

Synthesis of potent and highly selective inhibitors of human tryptase

Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors

Aminodiol HIV protease inhibitors. 2. 1,1-Dimethyl-2-hydroxyethyl carbamate derivatives with enhanced potency

A new detail in a complex case

Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells

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