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Rhabdomyolysis and myohemoglobinuric acute renal failure

Kidney international, 1996-02, Vol.49 (2), p.314-326

Zager, Richard A.

1996

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Acute nephrotoxic and obstructive injury primes the kidney to endotoxin-driven cytokine/chemokine production

Kidney international, 2006-04, Vol.69 (7), p.1181-1188

2006

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'Biologic memory' in response to acute kidney injury: cytoresistance, toll-like receptor hyper-responsiveness and the onset of progressive renal disease

Nephrology, dialysis, transplantation, 2013-08, Vol.28 (8), p.1985-1993

Zager, Richard A

2013

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Ischemic proximal tubular injury primes mice to endotoxin-induced TNF-alpha generation and systemic release

American journal of physiology. Renal physiology, 2005-08, Vol.289 (2), p.F289-F297

2005

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Hypocalcemia: A pervasive metabolic abnormality in the critically ill

American journal of kidney diseases, 2001-04, Vol.37 (4), p.689-698

2001

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Combined mannitol and deferoxamine therapy for myohemoglobinuric renal injury and oxidant tubular stress : mechanistic and therapeutic implications

The Journal of clinical investigation, 1992-09, Vol.90 (3), p.711-719

ZAGER, R. A

1992

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HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney

Kidney international, 1994-01, Vol.45 (1), p.48-57

1994

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Renal cortical cholesterol accumulation is an integral component of the systemic stress response

Kidney international, 2001-12, Vol.60 (6), p.2299-2310

2001

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Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression

Leukemia research, 2003-02, Vol.27 (2), p.133-145

2003

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Polyene antibiotics: Relative degrees of in vitro cytotoxicity and potential effects on tubule phospholipid and ceramide content

American journal of kidney diseases, 2000-08, Vol.36 (2), p.238-249

Zager, Richard A.

2000

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Plasma membrane cholesterol: A critical determinant of cellular energetics and tubular resistance to attack

Kidney international, 2000-07, Vol.58 (1), p.193-205

Zager, Richard A.

2000

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Myoglobin toxicity in proximal human kidney cells: Roles of Fe, Ca2+, H2O2, and terminal mitochondrial electron transport

Kidney international, 1997-03, Vol.51 (3), p.728-738

1997

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Mitochondrial free radical production induces lipid peroxidation during myohemoglobinuria

Kidney international, 1996-03, Vol.49 (3), p.741-751

Zager, Richard A.

1996

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Studies of mechanisms and protective maneuvers in myoglobinuric acute renal injury

Laboratory investigation, 1989-05, Vol.60 (5), p.619

Zager, R A

1989

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Changes in Free and Esterified Cholesterol : Hallmarks of Acute Renal Tubular Injury and Acquired Cytoresistance

The American journal of pathology, 2000-09, Vol.157 (3), p.1007-1016

2000

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Increased proximal tubular cholesterol content: Implications for cell injury and “acquired cytoresistance”

Kidney international, 1999-11, Vol.56 (5), p.1788-1797

1999

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Inorganic fluoride. Divergent effects on human proximal tubular cell viability

The American journal of pathology, 1997-02, Vol.150 (2), p.735-745

1997

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Iron, heme oxygenase, and glutathione: Effects on myohemoglobinuric proximal tubular injury

Kidney international, 1995-11, Vol.48 (5), p.1624-1634

1995

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Effects of inorganic iron and myoglobin on in vitro proximal tubular lipid peroxidation and cytotoxicity

The Journal of clinical investigation, 1992-03, Vol.89 (3), p.989-995

1992

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Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys

Kidney international, 1995-06, Vol.47 (6), p.1806-1810

1995

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An evaluation of renal tubular DNA laddering in response to oxygen deprivation and oxidant injury

Journal of the American Society of Nephrology, 1994-12, Vol.5 (6), p.1307-1313

1994

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Pathogenetic mechanisms in experimental hemoglobinuric acute renal failure

American journal of physiology. Renal physiology, 1989-03, Vol.256 (3), p.446-F455

1989

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Differential effects of glutathione and cysteine on Fe2+, Fe3+, H2O2 and myoglobin-induced proximal tubular cell attack

Kidney international, 1998-06, Vol.53 (6), p.1661-1672

1998

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Acute renal failure after cardiopulmonary bypass is related to decreased serum ferritin levels

Journal of the American Society of Nephrology, 1999-11, Vol.10 (11), p.2396-2402

1999

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Calcitriol Directly Sensitizes Renal Tubular Cells to ATP-Depletion- and Iron-Mediated Attack

The American journal of pathology, 1999-06, Vol.154 (6), p.1899-1909

Zager, Richard A.

1999

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Rhabdomyolysis and myohemoglobinuric acute renal failure

Acute nephrotoxic and obstructive injury primes the kidney to endotoxin-driven cytokine/chemokine production

'Biologic memory' in response to acute kidney injury: cytoresistance, toll-like receptor hyper-responsiveness and the onset of progressive renal disease

Ischemic proximal tubular injury primes mice to endotoxin-induced TNF-alpha generation and systemic release

Hypocalcemia: A pervasive metabolic abnormality in the critically ill

Combined mannitol and deferoxamine therapy for myohemoglobinuric renal injury and oxidant tubular stress : mechanistic and therapeutic implications

HK-2: An immortalized proximal tubule epithelial cell line from normal adult human kidney

Renal cortical cholesterol accumulation is an integral component of the systemic stress response

Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression

Polyene antibiotics: Relative degrees of in vitro cytotoxicity and potential effects on tubule phospholipid and ceramide content

Plasma membrane cholesterol: A critical determinant of cellular energetics and tubular resistance to attack

Myoglobin toxicity in proximal human kidney cells: Roles of Fe, Ca2+, H2O2, and terminal mitochondrial electron transport

Mitochondrial free radical production induces lipid peroxidation during myohemoglobinuria

Studies of mechanisms and protective maneuvers in myoglobinuric acute renal injury

Changes in Free and Esterified Cholesterol : Hallmarks of Acute Renal Tubular Injury and Acquired Cytoresistance

Increased proximal tubular cholesterol content: Implications for cell injury and “acquired cytoresistance”

Inorganic fluoride. Divergent effects on human proximal tubular cell viability

Iron, heme oxygenase, and glutathione: Effects on myohemoglobinuric proximal tubular injury

Effects of inorganic iron and myoglobin on in vitro proximal tubular lipid peroxidation and cytotoxicity

Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys

An evaluation of renal tubular DNA laddering in response to oxygen deprivation and oxidant injury

Pathogenetic mechanisms in experimental hemoglobinuric acute renal failure

Differential effects of glutathione and cysteine on Fe2+, Fe3+, H2O2 and myoglobin-induced proximal tubular cell attack

Acute renal failure after cardiopulmonary bypass is related to decreased serum ferritin levels

Calcitriol Directly Sensitizes Renal Tubular Cells to ATP-Depletion- and Iron-Mediated Attack

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