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Oral Treatment with PBI-4425 Decreases Fibrosis in Carbon Tetrachloride (CCL4)-Induced Hepatic Fibrosis Model

Journal of hepatology, 2016, Vol.64 (2), p.S228-S229

2016

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PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model

Journal of hepatology, 2016, Vol.64 (2), p.S707-S707

2016

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P72 ORAL TREATMENT WITH PBI-4050, A NOVEL FIRST-IN-CLASS ANTI-FIBROTIC COMPOUND, REDUCES HEPATIC FIBROSIS AND HEPATOCELLULAR CARCINOMA

Journal of hepatology, 2014-04, Vol.60 (1), p.S90-S90

2014

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A Mild Procedure for the Reduction of Pyridine N-Oxides to Piperidines Using Ammonium Formate

Journal of organic chemistry, 2001-07, Vol.66 (15), p.5264-5265

2001

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FRI-104 - PBI-4547 decreases hepatic stellate cell activation via AMPK signaling pathway, and reduces fibrosis in carbon tetrachloride (CCL4)-induced hepatic fibrosis model

Journal of hepatology, 2018-04, Vol.68, p.S408-S408

2018

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PBI-4547 decreases hepatic stellate cell activation via AMPK signaling pathway, and reduces fibrosis in carbon tetrachloride (CCL4)-induced hepatic fibrosis model

Journal of hepatology, 2018-04, Vol.68, p.S408

2018

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THU-281 - Oral Treatment with PBI-4425 Decreases Fibrosis in Carbon Tetrachloride (CCL4)-Induced Hepatic Fibrosis Model

Journal of hepatology, 2016, Vol.64 (2), p.S228-S229

2016

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SAT-405 - PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model

Journal of hepatology, 2016, Vol.64 (2), p.S707-S707

2016

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B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Pbi-4050 Reduces Inflammatory/fibrotic Markers In A Bleomycin-Induced Lung Fibrosis Model: A Comparative Study With Nintedanib

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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C74 MODELS AND METHODS IN LUNG BIOLOGY: Oral Treatment With Pbi-4050 Reduces Plasminogen Activator Inhibitor-1 (pai-1), Alpha-Smooth Muscle Actin ([alpha]-Sma) and Collagen Expression In Human Fibroblasts And Mice Fibrotic Lungs

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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B110 NOVEL THERAPIES AND TARGETS IN FIBROSIS: Oral Treatment With Pbi-4050 Reduces Serum And Lung Anti-Inflammatory/fibrotic Biomarkers

American journal of respiratory and critical care medicine, 2016-01, Vol.193, p.1

2016

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A60 LUNG FIBROSIS: ANIMAL MODELS I: Pbi-4050 Reduces Inflammatory/fibrotic Markers In A Bleomycin-Induced Lung Fibrosis Model: A Comparative Study With Pirfenidone

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Oral Treatment With Pbi-4050 Reduces Lung Fibrosis

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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Immunostimulant oxidized β-glucan conjugates

International immunopharmacology, 2001-03, Vol.1 (3), p.539-550

2001

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Synthesis of N-1-oxypyrimidine 1,3-dioxolane and 1,3-oxathiolane nucleosides

Chemical communications (Cambridge, England), 2000-01 (23), p.2311-2312

2000

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A Convenient, TiCl4/SnCl4-Mediated Synthesis of N-Phenyl or N-Aryl Benzamidines and N-Phenylpicolinamidines

ISRN Organic Chemistry, 2012-07, Vol.2012

2012

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Renal fibrosis and progression

Nephrology, dialysis, transplantation, 2013-05, Vol.28 (suppl 1), p.i27-i27

2013

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Enhancement of Th1 type cytokine production and primary T cell activation by PBI-1393

Clinical immunology (Orlando, Fla.), 2007-12, Vol.125 (3), p.318-327

2007

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Diabetes - basic research

Nephrology, dialysis, transplantation, 2013-05, Vol.28 (suppl 1), p.i50-i51

2013

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Thioamides: Synthesis, Stability, and Immunological Activities of Thioanalogues of Imreg. Preparation of New Thioacylating Agents Using Fluorobenzimidazolone Derivatives

Journal of medicinal chemistry, 1999-06, Vol.42 (11), p.2046-2052

1999

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Synergistic anti-tumor activity of a novel immunomodulator, BCH-1393, in combination with cyclophosphamide

International journal of immunopharmacology, 2000-09, Vol.22 (9), p.659-671

2000

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Synthesis and anti-HIV activity of 1,3-dithiolane nucleosides

Chemical communications (Cambridge, England), 1999-07 (13), p.1245-1246

1999

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Synthesis and antiviral activities of N-9-oxypurine 1,3-Dioxolane and 1,3-oxathiolane nucleosides

Bioorganic & medicinal chemistry letters, 2000-10, Vol.10 (19), p.2223-2226

2000

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Thioacylating agents. Use of thiobenzimidazolone derivatives for the preparation of thiotuftsin analogs

Tetrahedron, 1993, Vol.49 (46), p.10489-10500

1993

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A short synthesis of 4-substituted 1-(hydroxyalkyl)-1H-pyrazolo[3,4-d]pyrimidines

Tetrahedron, 1996-02, Vol.52 (7), p.2271-2278

1996

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Oral Treatment with PBI-4425 Decreases Fibrosis in Carbon Tetrachloride (CCL4)-Induced Hepatic Fibrosis Model

PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model

P72 ORAL TREATMENT WITH PBI-4050, A NOVEL FIRST-IN-CLASS ANTI-FIBROTIC COMPOUND, REDUCES HEPATIC FIBROSIS AND HEPATOCELLULAR CARCINOMA

A Mild Procedure for the Reduction of Pyridine N-Oxides to Piperidines Using Ammonium Formate

FRI-104 - PBI-4547 decreases hepatic stellate cell activation via AMPK signaling pathway, and reduces fibrosis in carbon tetrachloride (CCL4)-induced hepatic fibrosis model

PBI-4547 decreases hepatic stellate cell activation via AMPK signaling pathway, and reduces fibrosis in carbon tetrachloride (CCL4)-induced hepatic fibrosis model

THU-281 - Oral Treatment with PBI-4425 Decreases Fibrosis in Carbon Tetrachloride (CCL4)-Induced Hepatic Fibrosis Model

SAT-405 - PBI-4050 Decreases Hepatic Stellate Cell Activation and Ameliorates Fibrosis in Carbon Tetrachloride (CCL4)- Induced Hepatic Fibrosis Model

B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Pbi-4050 Reduces Inflammatory/fibrotic Markers In A Bleomycin-Induced Lung Fibrosis Model: A Comparative Study With Nintedanib

C74 MODELS AND METHODS IN LUNG BIOLOGY: Oral Treatment With Pbi-4050 Reduces Plasminogen Activator Inhibitor-1 (pai-1), Alpha-Smooth Muscle Actin ([alpha]-Sma) and Collagen Expression In Human Fibroblasts And Mice Fibrotic Lungs

B110 NOVEL THERAPIES AND TARGETS IN FIBROSIS: Oral Treatment With Pbi-4050 Reduces Serum And Lung Anti-Inflammatory/fibrotic Biomarkers

A60 LUNG FIBROSIS: ANIMAL MODELS I: Pbi-4050 Reduces Inflammatory/fibrotic Markers In A Bleomycin-Induced Lung Fibrosis Model: A Comparative Study With Pirfenidone

B56 SCAR WARS: INSIGHTS INTO MECHANISMS AND TREATMENTS OF PULMONARY FIBROSIS: Oral Treatment With Pbi-4050 Reduces Lung Fibrosis

Immunostimulant oxidized β-glucan conjugates

Synthesis of N-1-oxypyrimidine 1,3-dioxolane and 1,3-oxathiolane nucleosides

A Convenient, TiCl4/SnCl4-Mediated Synthesis of N-Phenyl or N-Aryl Benzamidines and N-Phenylpicolinamidines

Renal fibrosis and progression

Enhancement of Th1 type cytokine production and primary T cell activation by PBI-1393

Diabetes - basic research

Thioamides: Synthesis, Stability, and Immunological Activities of Thioanalogues of Imreg. Preparation of New Thioacylating Agents Using Fluorobenzimidazolone Derivatives

Synergistic anti-tumor activity of a novel immunomodulator, BCH-1393, in combination with cyclophosphamide

Synthesis and anti-HIV activity of 1,3-dithiolane nucleosides

Synthesis and antiviral activities of N-9-oxypurine 1,3-Dioxolane and 1,3-oxathiolane nucleosides

Thioacylating agents. Use of thiobenzimidazolone derivatives for the preparation of thiotuftsin analogs

A short synthesis of 4-substituted 1-(hydroxyalkyl)-1H-pyrazolo[3,4-d]pyrimidines

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