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Pharmacogenetics/genomics and personalized medicine

Human molecular genetics, 2005-10, Vol.14 (suppl-2), p.R207-R214

2005

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Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance

Cancer research (Chicago, Ill.), 2005-08, Vol.65 (16), p.7446-7454

2005

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MicroRNAs modulate the chemosensitivity of tumor cells

Molecular cancer therapeutics, 2008-01, Vol.7 (1), p.1-9

2008

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Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia

Cancer chemotherapy and pharmacology, 2007-03, Vol.59 (4), p.495-505

2007

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MicroRNA expression profiles for the NCI-60 cancer cell panel

Molecular cancer therapeutics, 2007-05, Vol.6 (5), p.1483-1491

2007

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Membrane transporters and channels: Role of the transportome in Cancer chemosensitivity and chemoresistance

Cancer research (Chicago, Ill.), 2004-06, Vol.64 (12), p.4294-4301

2004

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Deletions of the PRKAR1A Locus at 17q24.2-q24.3 in Carney Complex: Genotype-Phenotype Correlations and Implications for Genetic Testing

The journal of clinical endocrinology and metabolism, 2014-01, Vol.99 (1), p.E183-E188

2014

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A Multi-Institutional Phase II Study of the Efficacy and Tolerability of Lapatinib in Patients with Advanced Hepatocellular Carcinomas

Clinical cancer research, 2009-09, Vol.15 (18), p.5895-5901

2009

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Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues

Pharmacogenetics and genomics, 2008-09, Vol.18 (9), p.781-791

2008

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Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia

Nature genetics, 2005-03, Vol.37 (3), p.265-274

2005

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Chemoinformatics Analysis Identifies Cytotoxic Compounds Susceptible to Chemoresistance Mediated by Glutathione and Cystine/Glutamate Transport System xc

Journal of medicinal chemistry, 2007-04, Vol.50 (8), p.1896-1906

2007

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Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition

PloS one, 2010-11, Vol.5 (11), p.e13792

2010

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Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells

Oncogene, 2001-11, Vol.20 (53), p.7787-7796

2001

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A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes

Human molecular genetics, 2003-04, Vol.12 (7), p.791-801

2003

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Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomas

Molecular cytogenetics, 2012, Vol.5 (1), p.44-44

2012

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Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas : Implications for tumor biology and potential clinical utility

Oncogene, 2001-08, Vol.20 (36), p.5033-5042

2001

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Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines

The Journal of pharmacology and experimental therapeutics, 2005-07, Vol.314 (1), p.467-475

2005

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Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.268-276

2005

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LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer

Oncogene, 2003-02, Vol.22 (8), p.1243-1246

2003

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Cystine-Glutamate Transporter SLC7A11 Mediates Resistance to Geldanamycin but Not to 17-(Allylamino)-17-demethoxygeldanamycin

Molecular pharmacology, 2007-12, Vol.72 (6), p.1637-1646

2007

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Genotyping panel for assessing response to cancer chemotherapy

BMC medical genomics, 2008-06, Vol.1 (1), p.24-24, Article 24

2008

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Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1

Pharmaceutical research, 2007-09, Vol.24 (9), p.1702-1712

2007

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Haploinsufficiency of HDAC4 does not cause intellectual disability in all affected individuals

American journal of medical genetics. Part A, 2014-07, Vol.164A (7), p.1826-1829

2014

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Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci

Blood, 2001-05, Vol.97 (10), p.3226-3233

2001

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Pharmacogenetics/genomics and personalized medicine

Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance

MicroRNAs modulate the chemosensitivity of tumor cells

Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia

MicroRNA expression profiles for the NCI-60 cancer cell panel

Membrane transporters and channels: Role of the transportome in Cancer chemosensitivity and chemoresistance

Deletions of the PRKAR1A Locus at 17q24.2-q24.3 in Carney Complex: Genotype-Phenotype Correlations and Implications for Genetic Testing

A Multi-Institutional Phase II Study of the Efficacy and Tolerability of Lapatinib in Patients with Advanced Hepatocellular Carcinomas

Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues

Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia

Chemoinformatics Analysis Identifies Cytotoxic Compounds Susceptible to Chemoresistance Mediated by Glutathione and Cystine/Glutamate Transport System xc

Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition

Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells

A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes

Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomas

Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas : Implications for tumor biology and potential clinical utility

Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines

Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1

LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer

Cystine-Glutamate Transporter SLC7A11 Mediates Resistance to Geldanamycin but Not to 17-(Allylamino)-17-demethoxygeldanamycin

Genotyping panel for assessing response to cancer chemotherapy

Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1

Restriction landmark genomic scanning (RLGS) spot identification by second generation virtual RLGS in multiple genomes with multiple enzyme combinations

Haploinsufficiency of HDAC4 does not cause intellectual disability in all affected individuals

Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci

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