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Identifying Optimal Biologic Doses of Everolimus (RAD001) in Patients With Cancer Based on the Modeling of Preclinical and Clinical Pharmacokinetic and Pharmacodynamic Data

Journal of clinical oncology, 2008-04, Vol.26 (10), p.1596-1602

2008

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Dual Inhibition of mTOR and Estrogen Receptor Signaling In vitro Induces Cell Death in Models of Breast Cancer

Clinical cancer research, 2005-07, Vol.11 (14), p.5319-5328

2005

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Comprehensive Mapping of p53 Pathway Alterations Reveals an Apparent Role for Both SNP309 and MDM2 Amplification in Sarcomagenesis

Clinical cancer research, 2011-02, Vol.17 (3), p.416-426

2011

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A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression

PloS one, 2019, Vol.14 (10), p.e0221635-e0221635

2019

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Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells

Cancer research (Chicago, Ill.), 2004, Vol.64 (1), p.252-261

2004

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Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts

Bone (New York, N.Y.), 2004-11, Vol.35 (5), p.1144-1156

2004

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Inhibition of Cyclin-Dependent Kinase 4 (Cdk4) by Fascaplysin, a Marine Natural Product

Biochemical and biophysical research communications, 2000-09, Vol.275 (3), p.877-884

2000

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Integrated CRISPR screening and drug profiling identifies combination opportunities for EGFR, ALK, and BRAF/MEK inhibitors

Cell reports (Cambridge), 2023-04, Vol.42 (4), p.112297-112297, Article 112297

2023

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Selective In Vivo and In Vitro Effects of a Small Molecule Inhibitor of Cyclin-Dependent Kinase 4

JNCI : Journal of the National Cancer Institute, 2001-03, Vol.93 (6), p.436-446

2001

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A conditional inducible JAK2.sup.V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression

PloS one, 2019-10, Vol.14 (10), p.e0221635

2019

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DNA binding protein dbpA binds Cdk5 and inhibits its activity

FEBS letters, 1999-03, Vol.446 (2), p.343-350

1999

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Expression and purification of human recombinant GST-FGF receptor-1

Journal of biotechnology, 2001-03, Vol.86 (1), p.51-58

2001

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Identification of a Human cDNA Encoding a Kinase-Defective Cdk5 Isoform

Biochemical and biophysical research communications, 1998-12, Vol.253 (2), p.305-310

1998

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Selective In Vivo and In Vitro Effects of a Small Molecule Inhibitor of Cyclin-Dependent Kinase 4: p. 472

JNCI : Journal of the National Cancer Institute, 2001-03, Vol.93 (6), p.436

2001

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Identifying Optimal Biologic Doses of Everolimus (RAD001) in Patients With Cancer Based on the Modeling of Preclinical and Clinical Pharmacokinetic and Pharmacodynamic Data

Dual Inhibition of mTOR and Estrogen Receptor Signaling In vitro Induces Cell Death in Models of Breast Cancer

Comprehensive Mapping of p53 Pathway Alterations Reveals an Apparent Role for Both SNP309 and MDM2 Amplification in Sarcomagenesis

A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression

Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells

Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts

Inhibition of Cyclin-Dependent Kinase 4 (Cdk4) by Fascaplysin, a Marine Natural Product

Integrated CRISPR screening and drug profiling identifies combination opportunities for EGFR, ALK, and BRAF/MEK inhibitors

Selective In Vivo and In Vitro Effects of a Small Molecule Inhibitor of Cyclin-Dependent Kinase 4

A conditional inducible JAK2.sup.V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression

DNA binding protein dbpA binds Cdk5 and inhibits its activity

Expression and purification of human recombinant GST-FGF receptor-1

Identification of a Human cDNA Encoding a Kinase-Defective Cdk5 Isoform

Selective In Vivo and In Vitro Effects of a Small Molecule Inhibitor of Cyclin-Dependent Kinase 4: p. 472

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