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Auger electrons for cancer therapy – a review

EJNMMI radiopharmacy and chemistry, 2019-10, Vol.4 (1), p.27-27, Article 27

2019

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Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tumor xenografts to X-radiation

Breast cancer research and treatment, 2013-01, Vol.137 (1), p.81-91

2013

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DNA strand breaks induced by 0-4 eV electrons: The role of shape resonances

Physical review letters, 2004-08, Vol.93 (6), p.068101.1-068101.4, Article 068101

2004

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Design and Characterization of HER-2-Targeted Gold Nanoparticles for Enhanced X-radiation Treatment of Locally Advanced Breast Cancer

Molecular pharmaceutics, 2010-12, Vol.7 (6), p.2194-2206

2010

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Bispecific radioimmunoconjugates exploit receptor heterogeneity for positron emission tomography of tumors expressing HER2 and/or EGFR

iScience, 2024-05, Vol.27 (5), p.109750-109750, Article 109750

2024

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Role of Antibody-Mediated Tumor Targeting and Route of Administration in Nanoparticle Tumor Accumulation in Vivo

Molecular pharmaceutics, 2012-08, Vol.9 (8), p.2168-2179

2012

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[225Ac]Ac- and [111In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-positive human breast cancer xenografts

EJNMMI radiopharmacy and chemistry, 2023-09, Vol.8 (1), p.24-24, Article 24

2023

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Dose predictions for [177Lu]Lu-DOTA-panitumumab F(ab′)2 in NRG mice with HNSCC patient-derived tumour xenografts based on [64Cu]Cu-DOTA-panitumumab F(ab′)2 – implications for a PET theranostic strategy

EJNMMI radiopharmacy and chemistry, 2021-08, Vol.6 (1), p.1-22, Article 25

2021

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Radiation nanomedicines for cancer treatment: a scientific journey and view of the landscape

EJNMMI radiopharmacy and chemistry, 2024-05, Vol.9 (1), p.37-37, Article 37

2024

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Synthesis of Polyglutamide-Based Metal-Chelating Polymers and Their Site-Specific Conjugation to Trastuzumab for Auger Electron Radioimmunotherapy

Biomacromolecules, 2014-06, Vol.15 (6), p.2027-2037

2014

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Radioimmunotherapy of PANC-1 human pancreatic cancer xenografts in NOD/SCID or NRG mice with Panitumumab labeled with Auger electron emitting, 111In or β-particle emitting, 177Lu

EJNMMI radiopharmacy and chemistry, 2020-11, Vol.5 (1), p.1-19, Article 22

2020

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Dual-Receptor-Targeted Radioimmunotherapy of Human Breast Cancer Xenografts in Athymic Mice Coexpressing HER2 and EGFR Using 177Lu- or 111In-Labeled Bispecific Radioimmunoconjugates

The Journal of nuclear medicine (1978), 2016-03, Vol.57 (3), p.444-452

2016

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Investigation of Proton Transfer within DNA Base Pair Anion and Cation Radicals by Density Functional Theory (DFT)

The journal of physical chemistry. B, 2001-10, Vol.105 (41), p.10115-10123

2001

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Intracellular Routing in Breast Cancer Cells of Streptavidin-Conjugated Trastuzumab Fab Fragments Linked to Biotinylated Doxorubicin-Functionalized Metal Chelating Polymers

Biomacromolecules, 2014-03, Vol.15 (3), p.715-725

2014

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111In-labeled trastuzumab-modified gold nanoparticles are cytotoxic in vitro to HER2-positive breast cancer cells and arrest tumor growth in vivo in athymic mice after intratumoral injection

Nuclear medicine and biology, 2016-12, Vol.43 (12), p.818-826

2016

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Energetics of the Radical Ions of the AT and AU Base Pairs: A Density Functional Theory (DFT) Study

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2002-10, Vol.106 (40), p.9345-9351

2002

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Comparison between X-ray Photon and Secondary Electron Damage to DNA in Vacuum

The journal of physical chemistry. B, 2005-03, Vol.109 (10), p.4796-4800

2005

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Alkali-thermal humification treatment for simultaneous plant-growth-promoting compounds production and antibiotic removal from lincomycin fermentation residues

Chemical engineering journal (Lausanne, Switzerland : 1996), 2024-04, Vol.485, p.149449, Article 149449

2024

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Reinvestigation of the acid–base equilibrium of the (bi)carbonate radical and pH dependence of its reactivity with inorganic reactants

Radiation physics and chemistry (Oxford, England : 1993), 1999-06, Vol.55 (1), p.15-23

1999

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Excess Electron Transfer in DNA: Effect of Base Sequence and Proton Transfer

The journal of physical chemistry. B, 2002-03, Vol.106 (10), p.2755-2762

2002

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Panitumumab-DOTA- 111 In: An Epidermal Growth Factor Receptor Targeted Theranostic for SPECT/CT Imaging and Meitner–Auger Electron Radioimmunotherapy of Triple-Negative Breast Cancer

Molecular pharmaceutics, 2022-10, Vol.19 (10), p.3652-3663

2022

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Cellular dosimetry of 197Hg, 197mHg and 111In: comparison of dose deposition and identification of the cell and nuclear membrane as important targets

International journal of radiation biology, 2023-01, Vol.99 (1), p.53-63

2023

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111In- or 99mTc-labeled recombinant VEGF bioconjugates: in vitro evaluation of their cytotoxicity on porcine aortic endothelial cells overexpressing Flt-1 receptors

Nuclear medicine and biology, 2010-02, Vol.37 (2), p.105-115

2010

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111 In-Labeled Trastuzumab-Modified Gold Nanoparticles are Cytotoxic In Vitro to HER2-Positive Breast Cancer Cells and Arrest Tumor Growth In Vivo in Athymic Mice After Intratumoral Injection

Nuclear medicine and biology, 2016-12, Vol.43 (12), p.818

2016

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Abstract 6030: Optimizing the therapeutic index of targeted α-particle radioimmuotherapy (TART) of HER2-positive breast cancer tumors in NRG mice with 225Ac-labeled trastuzumab

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.6030-6030

2024

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Auger electrons for cancer therapy – a review

Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tumor xenografts to X-radiation

DNA strand breaks induced by 0-4 eV electrons: The role of shape resonances

Design and Characterization of HER-2-Targeted Gold Nanoparticles for Enhanced X-radiation Treatment of Locally Advanced Breast Cancer

Bispecific radioimmunoconjugates exploit receptor heterogeneity for positron emission tomography of tumors expressing HER2 and/or EGFR

Role of Antibody-Mediated Tumor Targeting and Route of Administration in Nanoparticle Tumor Accumulation in Vivo

[225Ac]Ac- and [111In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-positive human breast cancer xenografts

Dose predictions for [177Lu]Lu-DOTA-panitumumab F(ab′)2 in NRG mice with HNSCC patient-derived tumour xenografts based on [64Cu]Cu-DOTA-panitumumab F(ab′)2 – implications for a PET theranostic strategy

Radiation nanomedicines for cancer treatment: a scientific journey and view of the landscape

Synthesis of Polyglutamide-Based Metal-Chelating Polymers and Their Site-Specific Conjugation to Trastuzumab for Auger Electron Radioimmunotherapy

Radioimmunotherapy of PANC-1 human pancreatic cancer xenografts in NOD/SCID or NRG mice with Panitumumab labeled with Auger electron emitting, 111In or β-particle emitting, 177Lu

Dual-Receptor-Targeted Radioimmunotherapy of Human Breast Cancer Xenografts in Athymic Mice Coexpressing HER2 and EGFR Using 177Lu- or 111In-Labeled Bispecific Radioimmunoconjugates

Investigation of Proton Transfer within DNA Base Pair Anion and Cation Radicals by Density Functional Theory (DFT)

Intracellular Routing in Breast Cancer Cells of Streptavidin-Conjugated Trastuzumab Fab Fragments Linked to Biotinylated Doxorubicin-Functionalized Metal Chelating Polymers

111In-labeled trastuzumab-modified gold nanoparticles are cytotoxic in vitro to HER2-positive breast cancer cells and arrest tumor growth in vivo in athymic mice after intratumoral injection

Energetics of the Radical Ions of the AT and AU Base Pairs: A Density Functional Theory (DFT) Study

Comparison between X-ray Photon and Secondary Electron Damage to DNA in Vacuum

Alkali-thermal humification treatment for simultaneous plant-growth-promoting compounds production and antibiotic removal from lincomycin fermentation residues

Reinvestigation of the acid–base equilibrium of the (bi)carbonate radical and pH dependence of its reactivity with inorganic reactants

Excess Electron Transfer in DNA: Effect of Base Sequence and Proton Transfer

Panitumumab-DOTA- 111 In: An Epidermal Growth Factor Receptor Targeted Theranostic for SPECT/CT Imaging and Meitner–Auger Electron Radioimmunotherapy of Triple-Negative Breast Cancer

Cellular dosimetry of 197Hg, 197mHg and 111In: comparison of dose deposition and identification of the cell and nuclear membrane as important targets

111In- or 99mTc-labeled recombinant VEGF bioconjugates: in vitro evaluation of their cytotoxicity on porcine aortic endothelial cells overexpressing Flt-1 receptors

111 In-Labeled Trastuzumab-Modified Gold Nanoparticles are Cytotoxic In Vitro to HER2-Positive Breast Cancer Cells and Arrest Tumor Growth In Vivo in Athymic Mice After Intratumoral Injection

Abstract 6030: Optimizing the therapeutic index of targeted α-particle radioimmuotherapy (TART) of HER2-positive breast cancer tumors in NRG mice with 225Ac-labeled trastuzumab

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