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Advances and challenges in the treatment of esophageal cancer

Acta pharmaceutica Sinica. B, 2021-11, Vol.11 (11), p.3379-3392

2021

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Crizotinib enhances anti-CD30-LDM induced antitumor efficacy in NPM-ALK positive anaplastic large cell lymphoma

Cancer letters, 2019-04, Vol.448, p.84-93

2019

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A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer

Drug delivery, 2022-12, Vol.29 (1), p.1243-1256

2022

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A novel enediyne‐integrated antibody–drug conjugate shows promising antitumor efficacy against CD30+ lymphomas

Molecular oncology, 2018-03, Vol.12 (3), p.339-355

2018

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A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway

PloS one, 2018-02, Vol.13 (2), p.e0191984-e0191984

2018

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Construction of a genetically engineered chimeric apoprotein consisting of sequences derived from lidamycin and neocarzinostatin

Anti-cancer drugs, 2016-01, Vol.27 (1), p.24-28

2016

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An Engineered Fusion Protein Anti-CD19(Fab)-LDM Effectively Inhibits ADR-Resistant B Cell Lymphoma

Frontiers in oncology, 2019-09, Vol.9, p.861-861

2019

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Mithramycin suppresses tumor growth by regulating CD47 and PD-L1 expression

Biochemical pharmacology, 2022-03, Vol.197, p.114894-114894, Article 114894

2022

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Site-specific PEGylation of lidamycin and its antitumor activity

Acta pharmaceutica Sinica. B, 2015-05, Vol.5 (3), p.264-269

2015

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Binding capability of the enediyne-associated apoprotein to human tumors and constitution of a ligand oligopeptide-integrated protein

Journal of biotechnology, 2009-10, Vol.144 (2), p.142-150

2009

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A novel bivalent single-chain variable fragment (scFV) inhibits the action of tumour necrosis factor α

Biotechnology and applied biochemistry, 2008-08, Vol.50 (4), p.173-179

2008

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Antitumor effects of an engineered and energized fusion protein consisting of an anti-CD20 scFv fragment and lidamycin

Science China. Life sciences, 2011-03, Vol.54 (3), p.255-262

2011

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The recombinant EGFR/CD13 bi-targeted fusion protein induces apoptosis and blocks tube formation

Oncology reports, 2017-12, Vol.38 (6), p.3507-3514

2017

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An albumin‑binding domain and targeting peptide‑based recombinant protein and its enediyne‑integrated analogue exhibit directional delivery and potent inhibitory activity on pancreatic cancer with K‑ras mutation

Oncology reports, 2020-03, Vol.43 (3), p.851-863

2020

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Inhibition of histone deacetylases by trans-cinnamic acid and its antitumor effect against colon cancer xenografts in athymic mice

Molecular medicine reports, 2016-05, Vol.13 (5), p.4159-4166

2016

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A Macropinocytosis-Intensifying Albumin Domain-Based scFv Antibody and Its Conjugate Directed against K‑Ras Mutant Pancreatic Cancer

Molecular pharmaceutics, 2018-06, Vol.15 (6), p.2403-2412

2018

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Lidamycin Induces Apoptosis of B-Cell Lymphoma Cells and Inhibits Xenograft Growth in Nude Mice

Clinical oncology and cancer research, 2009-06, Vol.6 (3), p.203-207

2009

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Albumin‐Mediated Delivery of Bioactive Peptides for Pancreatic Cancer Therapy

Advanced therapeutics, 2020-07, Vol.3 (7), p.n/a

2020

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An EGFR/CD13 bispecific fusion protein and its enediyne-energized analog show potent antitumor activity

Anti-cancer drugs, 2014-01, Vol.25 (1), p.82-91

2014

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A tandem scFv-based fusion protein and its enediyne-energized analogue show intensified therapeutic efficacy against lung carcinoma xenograft in athymic mice

Cancer letters, 2010-09, Vol.295 (1), p.124-133

2010

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Inhibition of Tumor Metastasis by Sodium Caffeate and Its Effect on Angiogenesis

Oncology, 2004-01, Vol.67 (1), p.88-92

2004

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Antitumor efficacy of lidamycin against human multiple myeloma RPMI 8226 cells and the xenograft in nonobese diabetic/severe combined immunodeficiency mice

Journal of cancer research and therapeutics, 2016-01, Vol.12 (1), p.182-187

2016

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Generation and antitumor effects of an engineered and energized fusion protein VL-LDP-AE composed of single-domain antibody and lidamycin

Science China. Life sciences, 2007-08, Vol.50 (4), p.447-456

2007

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An arginine-rich cell penetrating peptide contained anti-gelatinase scFv-LDM fusion protein shows potent antitumor efficacy in pancreatic cancer

Journal of Cancer, 2018-01, Vol.9 (4), p.674-682

2018

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Antitumor effects of the molecule-downsized immunoconjugate composed of lidamycin and Fab' fragment of monoclonal antibody directed against type IV collagenase

Science China. Life sciences, 2004-02, Vol.47 (1), p.66-73

2004

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Advances and challenges in the treatment of esophageal cancer

Crizotinib enhances anti-CD30-LDM induced antitumor efficacy in NPM-ALK positive anaplastic large cell lymphoma

A recombinant scFv antibody-based fusion protein that targets EGFR associated with IMPDH2 downregulation and its drug conjugate show therapeutic efficacy against esophageal cancer

A novel enediyne‐integrated antibody–drug conjugate shows promising antitumor efficacy against CD30+ lymphomas

A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway

Construction of a genetically engineered chimeric apoprotein consisting of sequences derived from lidamycin and neocarzinostatin

An Engineered Fusion Protein Anti-CD19(Fab)-LDM Effectively Inhibits ADR-Resistant B Cell Lymphoma

Mithramycin suppresses tumor growth by regulating CD47 and PD-L1 expression

Site-specific PEGylation of lidamycin and its antitumor activity

Binding capability of the enediyne-associated apoprotein to human tumors and constitution of a ligand oligopeptide-integrated protein

A novel bivalent single-chain variable fragment (scFV) inhibits the action of tumour necrosis factor α

Antitumor effects of an engineered and energized fusion protein consisting of an anti-CD20 scFv fragment and lidamycin

The recombinant EGFR/CD13 bi-targeted fusion protein induces apoptosis and blocks tube formation

An albumin‑binding domain and targeting peptide‑based recombinant protein and its enediyne‑integrated analogue exhibit directional delivery and potent inhibitory activity on pancreatic cancer with K‑ras mutation

Inhibition of histone deacetylases by trans-cinnamic acid and its antitumor effect against colon cancer xenografts in athymic mice

A Macropinocytosis-Intensifying Albumin Domain-Based scFv Antibody and Its Conjugate Directed against K‑Ras Mutant Pancreatic Cancer

Lidamycin Induces Apoptosis of B-Cell Lymphoma Cells and Inhibits Xenograft Growth in Nude Mice

Albumin‐Mediated Delivery of Bioactive Peptides for Pancreatic Cancer Therapy

An EGFR/CD13 bispecific fusion protein and its enediyne-energized analog show potent antitumor activity

A tandem scFv-based fusion protein and its enediyne-energized analogue show intensified therapeutic efficacy against lung carcinoma xenograft in athymic mice

Inhibition of Tumor Metastasis by Sodium Caffeate and Its Effect on Angiogenesis

Antitumor efficacy of lidamycin against human multiple myeloma RPMI 8226 cells and the xenograft in nonobese diabetic/severe combined immunodeficiency mice

Generation and antitumor effects of an engineered and energized fusion protein VL-LDP-AE composed of single-domain antibody and lidamycin

An arginine-rich cell penetrating peptide contained anti-gelatinase scFv-LDM fusion protein shows potent antitumor efficacy in pancreatic cancer

Antitumor effects of the molecule-downsized immunoconjugate composed of lidamycin and Fab' fragment of monoclonal antibody directed against type IV collagenase

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