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The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors

Frontiers in immunology, 2023-01, Vol.13, p.1109938-1109938

2023

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Postoperative rehabilitation exercise experiences of geriatric patients with femoral neck fractures based on the perspective of medical staff: a qualitative study

BMC geriatrics, 2024-08, Vol.24 (1), p.667-11, Article 667

2024

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Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90

JCI insight, 2021-01, Vol.6 (2)

2021

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Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome

Acta pharmaceutica Sinica. B, 2019-07, Vol.9 (4), p.734-744

2019

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Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity

Cell communication and signaling, 2021-02, Vol.19 (1), p.13-14, Article 13

2021

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Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation

The Journal of experimental medicine, 2020-05, Vol.217 (5)

2020

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Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases

Cell death & disease, 2020-04, Vol.11 (4), p.252-252, Article 252

2020

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Pentagalloylglucose alleviates acetaminophen-induced acute liver injury by modulating inflammation via cGAS-STING pathway

Molecular medicine (Cambridge, Mass.), 2024-09, Vol.30 (1), p.160-16, Article 160

2024

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Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate

mBio, 2018-09, Vol.9 (5)

2018

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Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis

Frontiers in pharmacology, 2023-04, Vol.14, p.1160445-1160445

2023

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Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC

Molecular medicine (Cambridge, Mass.), 2023-07, Vol.29 (1), p.84-84, Article 84

2023

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Icariside Ⅱ, a main compound in Epimedii Folium, induces idiosyncratic hepatotoxicity by enhancing NLRP3 inflammasome activation

Acta pharmaceutica Sinica. B, 2020-09, Vol.10 (9), p.1619-1633

2020

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Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo

Cellular immunology, 2020-03, Vol.349, p.104046-104046, Article 104046

2020

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Glabridin improves autoimmune disease in Trex1-deficient mice by reducing type I interferon production

Molecular medicine (Cambridge, Mass.), 2023-12, Vol.29 (1), p.167-167, Article 167

2023

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Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity

Frontiers of medicine, 2021-08, Vol.15 (4), p.594-607

2021

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Dipeptide PA3264 derived from rare and endangered Squama Manis is a novel bioactive peptide for the treatment of triple-negative breast cancer

Chinese medicine, 2024-08, Vol.19 (1), p.112-16

2024

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Schisandrin C enhances type I IFN response activation to reduce tumor growth and sensitize chemotherapy through antitumor immunity

Frontiers in pharmacology, 2024-08, Vol.15, p.1369563

2024

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Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation

Cell communication and signaling, 2023-05, Vol.21 (1), p.123-123, Article 123

2023

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Correction: Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding

Chinese medicine, 2024-10, Vol.19 (1), p.147-3, Article 147

2024

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Unveiling correlations between aristolochic acids and liver cancer: spatiotemporal heterogeneity phenomenon

Chinese medicine, 2024-09, Vol.19 (1), p.132-13, Article 132

2024

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Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding

Chinese medicine, 2024-08, Vol.19 (1), p.107-17, Article 107

2024

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The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages

Chinese medicine, 2024-03, Vol.19 (1), p.48-48, Article 48

2024

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Variational Bayesian Neural Network for Ensemble Flood Forecasting

Water (Basel), 2020-10, Vol.12 (10), p.2740

2020

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Dihydrotanshinone I Specifically Inhibits NLRP3 Inflammasome Activation and Protects Against Septic Shock In Vivo

Frontiers in pharmacology, 2021-10, Vol.12, p.750815-750815

2021

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The Cytosolic DNA-Sensing cGAS-STING Pathway in Liver Diseases

Frontiers in cell and developmental biology, 2021-07, Vol.9, p.717610-717610

2021

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The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors

Postoperative rehabilitation exercise experiences of geriatric patients with femoral neck fractures based on the perspective of medical staff: a qualitative study

Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90

Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome

Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity

Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation

Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases

Pentagalloylglucose alleviates acetaminophen-induced acute liver injury by modulating inflammation via cGAS-STING pathway

Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate

Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis

Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC

Icariside Ⅱ, a main compound in Epimedii Folium, induces idiosyncratic hepatotoxicity by enhancing NLRP3 inflammasome activation

Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo

Glabridin improves autoimmune disease in Trex1-deficient mice by reducing type I interferon production

Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity

Dipeptide PA3264 derived from rare and endangered Squama Manis is a novel bioactive peptide for the treatment of triple-negative breast cancer

Schisandrin C enhances type I IFN response activation to reduce tumor growth and sensitize chemotherapy through antitumor immunity

Tricyclic antidepressants induce liver inflammation by targeting NLRP3 inflammasome activation

Correction: Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding

Unveiling correlations between aristolochic acids and liver cancer: spatiotemporal heterogeneity phenomenon

Total tanshinones ameliorates cGAS-STING-mediated inflammatory and autoimmune diseases by affecting STING-IRF3 binding

The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages

Variational Bayesian Neural Network for Ensemble Flood Forecasting

Dihydrotanshinone I Specifically Inhibits NLRP3 Inflammasome Activation and Protects Against Septic Shock In Vivo

The Cytosolic DNA-Sensing cGAS-STING Pathway in Liver Diseases

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