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Privileged structure based ligands for melanocortin receptors—4,4-Disubstituted piperidine derivatives

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (14), p.3843-3846

2006

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Synthesis and Structure−Activity Relationships of Novel Arylpiperazines as Potent and Selective Agonists of the Melanocortin Subtype-4 Receptor

Journal of medicinal chemistry, 2004-01, Vol.47 (3), p.744-755

2004

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5-HT1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs

Neuroreport, 1997-07, Vol.8 (9), p.2237-2239

1997

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Privileged structure-based ligands for melanocortin receptors—tetrahydroquinolines, indoles, and aminotetralines

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (20), p.4459-4462

2005

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Novel Potent 5-HT1F Receptor Agonists: Structure−Activity Studies of a Series of Substituted N-[3-(1-Methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides

Journal of medicinal chemistry, 2003-07, Vol.46 (14), p.3060-3071

2003

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Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brain penetration and activity in the neurogenic dural inflammation model of migraine

Life sciences (1973), 1997-10, Vol.61 (21), p.2117-2126

1997

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[3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties

Naunyn-Schmiedeberg's archives of pharmacology, 2005-03, Vol.371 (3), p.169-177

2005

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Privileged structure based ligands for melanocortin receptors—Substituted benzylic piperazine derivatives

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (22), p.4973-4978

2005

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Synthesis and structure–activity relationships of novel dipeptides and reduced dipeptides as ligands for melanocortin subtype-4 receptor

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (9), p.2341-2346

2006

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N-[3-(2-Dimethylaminoethyl)-2-methyl-1H- indol-5-yl]-4-fluorobenzamide: A Potent, Selective, and Orally Active 5-HT1F Receptor Agonist Potentially Useful for Migraine Therapy

Journal of medicinal chemistry, 2001-11, Vol.44 (24), p.4031-4034

2001

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Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT1F receptor agonists

Bioorganic & medicinal chemistry letters, 2004-01, Vol.14 (1), p.167-170

2004

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N-Methyl-5-tert-butyltryptamine: A Novel, Highly Potent 5-HT1D Receptor Agonist

Journal of medicinal chemistry, 1999-02, Vol.42 (3), p.526-531

1999

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Substituted furo[3,2- b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists

Bioorganic & medicinal chemistry letters, 2004-01, Vol.14 (1), p.167-170

2004

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Multiple subtypes of serotonin receptors are expressed in rat sensory neurons in culture

The Journal of pharmacology and experimental therapeutics, 1998-12, Vol.287 (3), p.1119

1998

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Human Serotonin 1D Receptor is Encoded by a Subfamily of Two Distinct Genes: 5-HT1Dαand 5-HT1Dβ

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (8), p.3630-3634

1992

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The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine

The Journal of pharmacology and experimental therapeutics, 2000-08, Vol.294 (2), p.688

2000

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LY215840, a high-affinity 5-HT7 receptor ligand, blocks serotonin-induced relaxation in canine coronary artery

The Journal of pharmacology and experimental therapeutics, 1996-06, Vol.277 (3), p.1560

1996

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Ketanserin and ritanserin discriminate between recombinant human 5-HT1Dα and 5-HT1Dβ receptor subtypes

European journal of pharmacology, 1995-09, Vol.291 (1), p.9-15

1995

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Dual coupling of cloned human 5-hydroxytryptamine1D alpha and 5-hydroxytryptamine1D beta receptors stably expressed in murine fibroblasts: inhibition of adenylate cyclase and elevation of intracellular calcium concentrations via pertussis toxin-sensitive G protein(s)

Molecular pharmacology, 1993-09, Vol.44 (3), p.575-582

1993

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Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor

Molecular pharmacology, 1992-08, Vol.42 (2), p.180-185

1992

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Expression and pharmacological characterization of a canine 5-hydroxytryptamine1D receptor subtype

Molecular pharmacology, 1991-12, Vol.40 (6), p.1036-1042

1991

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Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides

Journal of medicinal chemistry, 2003-07, Vol.46 (14), p.3060-3071

2003

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Novel Potent 5-HT 1F Receptor Agonists: Structure−Activity Studies of a Series of Substituted N -[3-(1-Methyl-4-piperidinyl)-1 H -pyrrolo[3,2- b ]pyridin-5-yl]amides

Journal of medicinal chemistry, 2003-07, Vol.46 (14), p.3060-3071

2003

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Cloning, expression, and pharmacological characterization of a human α2B-adrenergic receptor

Molecular pharmacology, 1990, Vol.38 (5), p.681-688

1990

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Functional characterization of the recombinant human 5-hydroxytryptamine7(a) receptor isoform coupled to adenylate cyclase stimulation

The Journal of pharmacology and experimental therapeutics, 1998-11, Vol.287 (2), p.508

1998

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Privileged structure based ligands for melanocortin receptors—4,4-Disubstituted piperidine derivatives

Synthesis and Structure−Activity Relationships of Novel Arylpiperazines as Potent and Selective Agonists of the Melanocortin Subtype-4 Receptor

5-HT1F receptor agonists inhibit neurogenic dural inflammation in guinea pigs

Privileged structure-based ligands for melanocortin receptors—tetrahydroquinolines, indoles, and aminotetralines

Novel Potent 5-HT1F Receptor Agonists: Structure−Activity Studies of a Series of Substituted N-[3-(1-Methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides

Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brain penetration and activity in the neurogenic dural inflammation model of migraine

[3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties

Privileged structure based ligands for melanocortin receptors—Substituted benzylic piperazine derivatives

Synthesis and structure–activity relationships of novel dipeptides and reduced dipeptides as ligands for melanocortin subtype-4 receptor

N-[3-(2-Dimethylaminoethyl)-2-methyl-1H- indol-5-yl]-4-fluorobenzamide: A Potent, Selective, and Orally Active 5-HT1F Receptor Agonist Potentially Useful for Migraine Therapy

Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT1F receptor agonists

N-Methyl-5-tert-butyltryptamine: A Novel, Highly Potent 5-HT1D Receptor Agonist

Substituted furo[3,2- b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists

Multiple subtypes of serotonin receptors are expressed in rat sensory neurons in culture

Human Serotonin 1D Receptor is Encoded by a Subfamily of Two Distinct Genes: 5-HT1Dαand 5-HT1Dβ

The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine

LY215840, a high-affinity 5-HT7 receptor ligand, blocks serotonin-induced relaxation in canine coronary artery

Ketanserin and ritanserin discriminate between recombinant human 5-HT1Dα and 5-HT1Dβ receptor subtypes

Dual coupling of cloned human 5-hydroxytryptamine1D alpha and 5-hydroxytryptamine1D beta receptors stably expressed in murine fibroblasts: inhibition of adenylate cyclase and elevation of intracellular calcium concentrations via pertussis toxin-sensitive G protein(s)

Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor

Expression and pharmacological characterization of a canine 5-hydroxytryptamine1D receptor subtype

Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides

Novel Potent 5-HT 1F Receptor Agonists: Structure−Activity Studies of a Series of Substituted N -[3-(1-Methyl-4-piperidinyl)-1 H -pyrrolo[3,2- b ]pyridin-5-yl]amides

Cloning, expression, and pharmacological characterization of a human α2B-adrenergic receptor

Functional characterization of the recombinant human 5-hydroxytryptamine7(a) receptor isoform coupled to adenylate cyclase stimulation

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