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Structural Mechanism of the Bromodomain of the Coactivator CBP in p53 Transcriptional Activation

Molecular cell, 2004-01, Vol.13 (2), p.251-263

2004

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MLL Repression Domain Interacts with Histone Deacetylases, the Polycomb Group Proteins HPC2 and BMI-1, and the Corepressor C-Terminal-Binding Protein

Proceedings of the National Academy of Sciences - PNAS, 2003-07, Vol.100 (14), p.8342-8347

2003

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An In vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region

Blood, 1998-11, Vol.92 (10), p.3793-3803

1998

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Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints

Leukemia, 1998-12, Vol.12 (12), p.1895-1902

1998

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DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis

Human molecular genetics, 2000-07, Vol.9 (11), p.1671-1679

2000

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MSF (MLL Septin-Like Fusion), a Fusion Partner Gene of MLL, in a Therapy-Related Acute Myeloid Leukemia with a t(11;17)(q23;q25)

Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (11), p.6428-6433

1999

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Intergenic Splicing of MDS1 and EVI1 Occurs in Normal Tissues as well as in Myeloid Leukemia and Produces a New Member of the PR Domain Family

Proceedings of the National Academy of Sciences - PNAS, 1996-02, Vol.93 (4), p.1642-1647

1996

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Cryptic ins(2;11) with clonal evolution showing amplification of 11q23-q25 either on hsr(11) or on dmin, in a patient with AML-M2

Leukemia, 2004-12, Vol.18 (12), p.2041-2044

2004

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11q23 Translocations Split the "AT-Hook" Cruciform DNA-Binding Region and the Transcriptional Repression Domain from the Activation Domain of the Mixed-Lineage Leukemia (MLL) Gene

Proceedings of the National Academy of Sciences - PNAS, 1994-10, Vol.91 (22), p.10610-10614

1994

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A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15

Oncogene, 2003-03, Vol.22 (9), p.1400-1410

2003

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Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia

The EMBO journal, 2000-09, Vol.19 (17), p.4655-4664

2000

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MLL: How complex does it get?

Journal of cellular biochemistry, 2005-05, Vol.95 (2), p.234-242

2005

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Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14)

Oncogene, 2003-03, Vol.22 (9), p.1418-1424

2003

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A New Member of the Leucine Zipper Class of Proteins That Binds to the HLA DRα Promoter

Science (American Association for the Advancement of Science), 1990-03, Vol.247 (4950), p.1581-1584

1990

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A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome

Genes chromosomes & cancer, 2002-09, Vol.35 (1), p.11-19

2002

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MLL is Fused to CBP, a Histone Acetyltransferase, in Therapy-Related Acute Myeloid Leukemia with a t(11;16)(q23;p13.3)

Proceedings of the National Academy of Sciences - PNAS, 1997-08, Vol.94 (16), p.8732-8737

1997

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The partial nontandem duplication of the MLL (ALL1) gene is a novel rearrangement that generates three distinct fusion transcripts in B-cell acute lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2001, Vol.61 (1), p.59-63

2001

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The Human Programmed Cell Death-2 (PDCD2) Gene is a Target of BCL6 Repression: Implications for a Role of BCL6 in the Down-Regulation of Apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.2860-2865

2002

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Establishment and characterization of a megakaryoblast cell line with amplification of MLL

Leukemia, 1998-07, Vol.12 (7), p.1119-1127

1998

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All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders

Blood, 1997-07, Vol.90 (2), p.535-541

1997

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The MLL Fusion Gene, MLL-AF4, Regulates Cyclin-Dependent Kinase Inhibitor CDKN1B ( p27kip1) Expression

Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (39), p.14028-14033

2005

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Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia : Correlation with scaffold attachment regions and topoisomerase II consensus binding sites

Blood, 1996-03, Vol.87 (5), p.1912-1922

1996

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Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with an MLL-AF9 translocation

Genes chromosomes & cancer, 2000-12, Vol.29 (4), p.333-338

2000

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Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene

Proceedings of the National Academy of Sciences - PNAS, 1991-03, Vol.88 (5), p.1873-1877

1991

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Therapy-Related Acute Leukemia Associated With t(11q23) After Primary Acute Myeloid Leukemia With t(8;21): A Report of Two Cases

Blood, 1995-11, Vol.86 (9), p.3613-3614

1995

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Structural Mechanism of the Bromodomain of the Coactivator CBP in p53 Transcriptional Activation

MLL Repression Domain Interacts with Histone Deacetylases, the Polycomb Group Proteins HPC2 and BMI-1, and the Corepressor C-Terminal-Binding Protein

An In vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region

Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints

DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis

MSF (MLL Septin-Like Fusion), a Fusion Partner Gene of MLL, in a Therapy-Related Acute Myeloid Leukemia with a t(11;17)(q23;q25)

Intergenic Splicing of MDS1 and EVI1 Occurs in Normal Tissues as well as in Myeloid Leukemia and Produces a New Member of the PR Domain Family

Cryptic ins(2;11) with clonal evolution showing amplification of 11q23-q25 either on hsr(11) or on dmin, in a patient with AML-M2

11q23 Translocations Split the "AT-Hook" Cruciform DNA-Binding Region and the Transcriptional Repression Domain from the Activation Domain of the Mixed-Lineage Leukemia (MLL) Gene

A t(11;15) fuses MLL to two different genes, AF15q14 and a novel gene MPFYVE on chromosome 15

Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia

MLL: How complex does it get?

Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14)

A New Member of the Leucine Zipper Class of Proteins That Binds to the HLA DRα Promoter

A novel gene, MDS2, is fused to ETV6/TEL in a t(1;12)(p36.1;p13) in a patient with myelodysplastic syndrome

MLL is Fused to CBP, a Histone Acetyltransferase, in Therapy-Related Acute Myeloid Leukemia with a t(11;16)(q23;p13.3)

The partial nontandem duplication of the MLL (ALL1) gene is a novel rearrangement that generates three distinct fusion transcripts in B-cell acute lymphoblastic leukemia

The Human Programmed Cell Death-2 (PDCD2) Gene is a Target of BCL6 Repression: Implications for a Role of BCL6 in the Down-Regulation of Apoptosis

Establishment and characterization of a megakaryoblast cell line with amplification of MLL

All patients with the T(11;16)(q23;p13.3) that involves MLL and CBP have treatment-related hematologic disorders

The MLL Fusion Gene, MLL-AF4, Regulates Cyclin-Dependent Kinase Inhibitor CDKN1B ( p27kip1) Expression

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia : Correlation with scaffold attachment regions and topoisomerase II consensus binding sites

Cytogenetic and molecular analysis of the acute monocytic leukemia cell line THP-1 with an MLL-AF9 translocation

Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene

Therapy-Related Acute Leukemia Associated With t(11q23) After Primary Acute Myeloid Leukemia With t(8;21): A Report of Two Cases

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