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7-Phenyl-pyrido[2,3-d]pyrimidine-2,4-diamines: Novel and highly selective protein tyrosine phosphatase 1B inhibitors

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (24), p.7518-7522

2012

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C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (14), p.3835-3839

2007

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N-Acyl- l-phenylalanine derivatives as potent VLA-4 antagonists that mimic a cyclic peptide conformation

Bioorganic & medicinal chemistry letters, 2002-01, Vol.12 (2), p.137-140

2002

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CBI-TMI: Synthesis and Evaluation of a Key Analog of the Duocarmycins. Validation of a Direct Relationship between Chemical Solvolytic Stability and Cytotoxic Potency and Confirmation of the Structural Features Responsible for the Distinguishing Behavior of Enantiomeric Pairs of Agents

Journal of the American Chemical Society, 1994-09, Vol.116 (18), p.7996-8006

1994

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Reversibility of the duocarmycin A and SA DNA alkylation reaction

Journal of the American Chemical Society, 1993-10, Vol.115 (21), p.9872-9873

1993

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Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (10), p.2936-2940

2013

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An improved synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI): a simplified analog of the CC-1065 alkylation subunit

Journal of organic chemistry, 1992-05, Vol.57 (10), p.2873-2876

1992

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Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (23), p.7205-7209

2011

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Solid-phase synthesis of N-substituted amidinophenoxy pyridines as factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (14), p.1877-1882

1998

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Heck reaction on solid support: synthesis of indole analogs

Tetrahedron letters, 1996-09, Vol.37 (40), p.7189-7192

1996

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N-substituted sultam carboxylic acids as novel glycogen synthase activators

MedChemComm, 2013-05, Vol.4 (5), p.833-838

2013

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(+)- and ent-(-)-duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA alkylation properties. Alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity of the enantiomeric agents

Journal of the American Chemical Society, 1994-03, Vol.116 (5), p.1635-1656

1994

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1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation

Bioorganic & medicinal chemistry, 1995-11, Vol.3 (11), p.1429-1453

1995

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Solid-phase synthesis of diaryl ketones through a three-component Stille coupling reaction

Tetrahedron letters, 2001-01, Vol.42 (2), p.175-177

2001

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Molecular basis for sequence selective DNA alkylation by (+)- and ent-(−)-CC-1065 and related agents: Alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity

Bioorganic & medicinal chemistry, 1994-02, Vol.2 (2), p.115-135

1994

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1,2,9,9 a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation

Bioorganic & medicinal chemistry, 1995, Vol.3 (11), p.1429-1453

1995

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DNA alkylation properties of the duocarmycins: (+)-duocarmycin A, epi-(+)-duocarmycin A, ent-(−)-duocarmycin A and epi,ent-(−)-duocarmycin A

Bioorganic & medicinal chemistry letters, 1992, Vol.2 (7), p.759-765

1992

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CBI-CDPBO1 and CBI-CDPBI1: CC-1065 analogs containing deep-seated modifications in the DNA binding subunit

Bioorganic & medicinal chemistry, 1995-06, Vol.3 (6), p.761-775

1995

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CC-1065 CBI analogs: an example of enhancement of DNA alkylation efficiency through introduction of stabilizing electrostatic interactions

Bioorganic & medicinal chemistry, 1995-06, Vol.3 (6), p.611-621

1995

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Synthesis and evaluation of CBI-based agents: Enhanced functional analogs of the potent antitumor antibiotics (+)-CC-1065 and the duocarmycins

Yun, Weiya

1994

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ProQuest

Role of the CC-1065 and Duocarmycin N2 Substituent: Validation of a Direct Relationship between Solvolysis Chemical Stability and in vitro Biological Potency

Journal of the American Chemical Society, 1994-06, Vol.116 (12), p.5523-5524

1994

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CBI-CDPBO 1 and CBI-CDPBI 1: CC-1065 analogs containing deep-seated modifications in the DNA binding subunit

Bioorganic & medicinal chemistry, 1995, Vol.3 (6), p.761-775

1995

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(+)- and ent-(-)-duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA alkylation properties. Alkylation site models that accomodate the offset AT-rich adenine N3 alkylation selectivity of the enantiomeric agents

Journal of the American Chemical Society, 1994, Vol.116 (5), p.1635-1656

1994

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(+)- and ent-(-)-Duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA Alkylation Properties.Alkylation Site Models That Accommodate the Offset AT-Rich Adenine N3 Alkylation Selectivity of the Enantiomeric Agents

Journal of the American Chemical Society, 1994-03, Vol.116 (5), p.1635-1656

1994

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7-Phenyl-pyrido[2,3-d]pyrimidine-2,4-diamines: Novel and highly selective protein tyrosine phosphatase 1B inhibitors

C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase

N-Acyl- l-phenylalanine derivatives as potent VLA-4 antagonists that mimic a cyclic peptide conformation

CBI-TMI: Synthesis and Evaluation of a Key Analog of the Duocarmycins. Validation of a Direct Relationship between Chemical Solvolytic Stability and Cytotoxic Potency and Confirmation of the Structural Features Responsible for the Distinguishing Behavior of Enantiomeric Pairs of Agents

Reversibility of the duocarmycin A and SA DNA alkylation reaction

Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators

An improved synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI): a simplified analog of the CC-1065 alkylation subunit

Discovery of Orally Active Carboxylic Acid Derivatives of 2-Phenyl-5-trifluoromethyloxazole-4-carboxamide as Potent Diacylglycerol Acyltransferase-1 Inhibitors for the Potential Treatment of Obesity and Diabetes

Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors

Solid-phase synthesis of N-substituted amidinophenoxy pyridines as factor Xa inhibitors

Heck reaction on solid support: synthesis of indole analogs

N-substituted sultam carboxylic acids as novel glycogen synthase activators

(+)- and ent-(-)-duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA alkylation properties. Alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity of the enantiomeric agents

1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation

Solid-phase synthesis of diaryl ketones through a three-component Stille coupling reaction

Molecular basis for sequence selective DNA alkylation by (+)- and ent-(−)-CC-1065 and related agents: Alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity

1,2,9,9 a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation

DNA alkylation properties of the duocarmycins: (+)-duocarmycin A, epi-(+)-duocarmycin A, ent-(−)-duocarmycin A and epi,ent-(−)-duocarmycin A

CBI-CDPBO1 and CBI-CDPBI1: CC-1065 analogs containing deep-seated modifications in the DNA binding subunit

CC-1065 CBI analogs: an example of enhancement of DNA alkylation efficiency through introduction of stabilizing electrostatic interactions

Synthesis and evaluation of CBI-based agents: Enhanced functional analogs of the potent antitumor antibiotics (+)-CC-1065 and the duocarmycins

Role of the CC-1065 and Duocarmycin N2 Substituent: Validation of a Direct Relationship between Solvolysis Chemical Stability and in vitro Biological Potency

CBI-CDPBO 1 and CBI-CDPBI 1: CC-1065 analogs containing deep-seated modifications in the DNA binding subunit

(+)- and ent-(-)-duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA alkylation properties. Alkylation site models that accomodate the offset AT-rich adenine N3 alkylation selectivity of the enantiomeric agents

(+)- and ent-(-)-Duocarmycin SA and (+)- and ent-(-)-N-BOC-DSA DNA Alkylation Properties.Alkylation Site Models That Accommodate the Offset AT-Rich Adenine N3 Alkylation Selectivity of the Enantiomeric Agents

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