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Data integration of non-animal tests for the development of a test battery to predict the skin sensitizing potential and potency of chemicals

Toxicology in vitro, 2013-03, Vol.27 (2), p.609-618

2013

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Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency

Toxicology in vitro, 2012-10, Vol.26 (7), p.1150-1160

2012

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In silico systems for predicting chemical-induced side effects using known and potential chemical protein interactions, enabling mechanism estimation

The Journal of Toxicological Sciences, 2020, Vol.45(3), pp.137-149

2020

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Safety Pharmacological Evaluation of the Coffee Component, Caffeoylquinic Acid, and Its Metabolites, Using Ex Vivo and In Vitro Profiling Assays

Pharmaceuticals (Basel, Switzerland), 2019-07, Vol.12 (3), p.110

2019

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Comparative Evaluation of In Vitro Skin Sensitisation Tests: The Human Cell-line Activation Test (h-CLAT) versus the Local Lymph Node Assay (LLNA)

Alternatives to laboratory animals, 2010-08, Vol.38 (4), p.275-284

2010

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Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT)

Contact dermatitis, 2011-12, Vol.65 (6), p.343-353

2011

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Predictive performance and inter-laboratory reproducibility in assessing eye irritation potential of water- and oil-soluble mixtures using the Short Time Exposure test method

Toxicology in vitro, 2018-04, Vol.48, p.78-85

2018

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Definition of the applicability domain of the Short Time Exposure (STE) test for predicting the eye irritation of chemicals

Alternatives to laboratory animals, 2013-05, Vol.41 (2), p.157-171

2013

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Production of IL-8 in THP-1 cells following contact allergen stimulation via mitogen-activated protein kinase activation or tumor necrosis factor-α production

The Journal of Toxicological Sciences, 2008/05/01, Vol.33(2), pp.175-185

2008

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Alteration of Phosphatidylinositol 3-Kinase Cascade in the Multilobulated Nuclear Formation of Adult T Cell Leukemia/Lymphoma (ATLL)

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (42), p.15213-15218

2005

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Effects of internal hydrophilic groups of a newly developed sustainable anionic surfactant on biodegradability and ecotoxicity

Chemosphere (Oxford), 2022-01, Vol.286, p.131676-131676, Article 131676

2022

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The relationship between CD86 and CD54 protein expression and cytotoxicity following stimulation with contact allergen in THP-1 cells

The Journal of Toxicological Sciences, 2011/06/01, Vol.36(3), pp.313-324

2011

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Investigating the uncertainty of prediction accuracy for the application of physiologically based pharmacokinetic models to animal-free risk assessment of cosmetic ingredients

Regulatory toxicology and pharmacology, 2022-11, Vol.135, p.105262-105262, Article 105262

2022

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Comparison of toxicological effects and exposure levels between triclosan and its structurally similar chemicals using in vitro tests for read-across case study

Regulatory toxicology and pharmacology, 2022-07, Vol.132, p.105181-105181, Article 105181

2022

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An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens

Toxicology in vitro, 2017-04, Vol.40, p.11-25

2017

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Grouping of chemicals based on the potential mechanisms of hepatotoxicity of naphthalene and structurally similar chemicals using in vitro testing for read-across and its validation

Regulatory toxicology and pharmacology, 2021-04, Vol.121, p.104874, Article 104874

2021

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AILIM/ICOS-mediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade

International immunology, 2006-12, Vol.18 (12), p.1815-1824

2006

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Comparison of the potential mechanisms for hepatotoxicity of p-dialkoxy chlorobenzenes in rat primary hepatocytes for read-across

Regulatory toxicology and pharmacology, 2020-06, Vol.113, p.104617, Article 104617

2020

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Role of TNF-α and extracellular ATP in THP-1 cell activation following allergen exposure

The Journal of Toxicological Sciences, 2008, Vol.33(1), pp.71-83

2008

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4″-Sulfation Is the Major Metabolic Pathway of Epigallocatechin-3-gallate in Humans: Characterization of Metabolites, Enzymatic Analysis, and Pharmacokinetic Profiling

Journal of agricultural and food chemistry, 2022-07, Vol.70 (27), p.8264-8273

2022

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AILIM/ICOS signaling induces T-cell migration/polarization of memory/effector T-cells

International immunology, 2004-10, Vol.16 (10), p.1515-1522

2004

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A 90-day repeated-dose toxicity study of dietary alpha linolenic acid-enriched diacylglycerol oil in rats

Regulatory toxicology and pharmacology, 2018-08, Vol.97, p.33-47

2018

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Effects of dietary alpha-linolenic acid-enriched diacylglycerol oil on embryo/fetal development in rats

Regulatory toxicology and pharmacology, 2018-10, Vol.98, p.108-114

2018

Volltextzugriff (PDF)

Development of a new in vitro skin sensitization assay (Epidermal Sensitization Assay; EpiSensA) using reconstructed human epidermis

Toxicology in vitro, 2013-12, Vol.27 (8), p.2213-2224

2013

Volltextzugriff (PDF)

Development of an in vitro skin sensitization test based on ROS production in THP-1 cells

Toxicology in vitro, 2013-03, Vol.27 (2), p.857-863

2013

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Data integration of non-animal tests for the development of a test battery to predict the skin sensitizing potential and potency of chemicals

Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency

In silico systems for predicting chemical-induced side effects using known and potential chemical protein interactions, enabling mechanism estimation

Safety Pharmacological Evaluation of the Coffee Component, Caffeoylquinic Acid, and Its Metabolites, Using Ex Vivo and In Vitro Profiling Assays

Comparative Evaluation of In Vitro Skin Sensitisation Tests: The Human Cell-line Activation Test (h-CLAT) versus the Local Lymph Node Assay (LLNA)

Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT)

Predictive performance and inter-laboratory reproducibility in assessing eye irritation potential of water- and oil-soluble mixtures using the Short Time Exposure test method

Definition of the applicability domain of the Short Time Exposure (STE) test for predicting the eye irritation of chemicals

Production of IL-8 in THP-1 cells following contact allergen stimulation via mitogen-activated protein kinase activation or tumor necrosis factor-α production

Alteration of Phosphatidylinositol 3-Kinase Cascade in the Multilobulated Nuclear Formation of Adult T Cell Leukemia/Lymphoma (ATLL)

Effects of internal hydrophilic groups of a newly developed sustainable anionic surfactant on biodegradability and ecotoxicity

The relationship between CD86 and CD54 protein expression and cytotoxicity following stimulation with contact allergen in THP-1 cells

Investigating the uncertainty of prediction accuracy for the application of physiologically based pharmacokinetic models to animal-free risk assessment of cosmetic ingredients

Comparison of toxicological effects and exposure levels between triclosan and its structurally similar chemicals using in vitro tests for read-across case study

An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens

Grouping of chemicals based on the potential mechanisms of hepatotoxicity of naphthalene and structurally similar chemicals using in vitro testing for read-across and its validation

AILIM/ICOS-mediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade

Comparison of the potential mechanisms for hepatotoxicity of p-dialkoxy chlorobenzenes in rat primary hepatocytes for read-across

Role of TNF-α and extracellular ATP in THP-1 cell activation following allergen exposure

4″-Sulfation Is the Major Metabolic Pathway of Epigallocatechin-3-gallate in Humans: Characterization of Metabolites, Enzymatic Analysis, and Pharmacokinetic Profiling

AILIM/ICOS signaling induces T-cell migration/polarization of memory/effector T-cells

A 90-day repeated-dose toxicity study of dietary alpha linolenic acid-enriched diacylglycerol oil in rats

Effects of dietary alpha-linolenic acid-enriched diacylglycerol oil on embryo/fetal development in rats

Development of a new in vitro skin sensitization assay (Epidermal Sensitization Assay; EpiSensA) using reconstructed human epidermis

Development of an in vitro skin sensitization test based on ROS production in THP-1 cells

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