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Support Vector Machine model for hERG inhibitory activities based on the integrated hERG database using descriptor selection by NSGA-II

Scientific reports, 2019-08, Vol.9 (1), p.12220-12, Article 12220

2019

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Construction of an integrated database for hERG blocking small molecules

PloS one, 2018-07, Vol.13 (7), p.e0199348

2018

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The Genetics of Primary Biliary Cholangitis: A GWAS and Post-GWAS Update

Genes, 2023-02, Vol.14 (2), p.405

2023

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Clinical application of exome sequencing in undiagnosed genetic conditions

Journal of medical genetics, 2012-06, Vol.49 (6), p.353-361

2012

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Analysis of whole Y-chromosome sequences reveals the Japanese population history in the Jomon period

Scientific reports, 2019-06, Vol.9 (1), p.8556-8, Article 8556

2019

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Principal contribution of HLA-DQ alleles, DQB106:04 and DQB103:01, to disease resistance against primary biliary cholangitis in a Japanese population

Scientific reports, 2017-09, Vol.7 (1), p.11093-10, Article 11093

2017

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rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis

Scientific reports, 2021-02, Vol.11 (1), p.4557-4557, Article 4557

2021

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FMODB: The World’s First Database of Quantum Mechanical Calculations for Biomacromolecules Based on the Fragment Molecular Orbital Method

Journal of chemical information and modeling, 2021-02, Vol.61 (2), p.777-794

2021

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Inhibitory effects of biseokeaniamide A against lipopolysaccharide-induced signal transduction

Bioorganic & medicinal chemistry letters, 2020-06, Vol.30 (11), p.127069, Article 127069

2020

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Identification of HLA-A02:06:01 as the primary disease susceptibility HLA allele in cold medicine-related Stevens-Johnson syndrome with severe ocular complications by high-resolution NGS-based HLA typing

Scientific reports, 2019-11, Vol.9 (1), p.16240-8, Article 16240

2019

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rs10924104 in the expression enhancer motif of CD58 confers susceptibility to human autoimmune diseases

Human genetics, 2024-01, Vol.143 (1), p.19-33

2024

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Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

Journal of medicinal chemistry, 2019-04, Vol.62 (7), p.3407-3427

2019

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Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer

Journal of medicinal chemistry, 2020-04, Vol.63 (8), p.4183-4204

2020

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Mutation in TECPR2 Reveals a Role for Autophagy in Hereditary Spastic Paraparesis

American journal of human genetics, 2012-12, Vol.91 (6), p.1065-1072

2012

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Significance of functional disease-causal/susceptible variants identified by whole-genome analyses for the understanding of human diseases

Proceedings of the Japan Academy, Series B, 2017/11/10, Vol.93(9), pp.657-676

2017

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The ubiquinone synthesis pathway is a promising drug target for Chagas disease

PloS one, 2021-02, Vol.16 (2), p.e0243855-e0243855

2021

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Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis

Scientific reports, 2017-06, Vol.7 (1), p.2904-10, Article 2904

2017

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Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population

European journal of human genetics : EJHG, 2021-08, Vol.29 (8), p.1282-1291

2021

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Prediction of sites of metabolism in a substrate molecule, instanced by carbamazepine oxidation by CYP3A4

Bioorganic & medicinal chemistry, 2012-01, Vol.20 (2), p.775-783

2012

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Statistical analysis of interactions among amino acid residues in apo structures using fragment molecular orbital method

Chem-Bio Informatics Journal, 2024/06/28, Vol.24, pp.25-47

2024

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A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides

Journal of autoimmunity, 2021-01, Vol.116, p.102571-102571, Article 102571

2021

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Quantitative prediction of hERG inhibitory activities using support vector regression and the integrated hERG dataset in AMED cardiotoxicity database

Chem-Bio Informatics Journal, 2021/10/01, Vol.21, pp.70-80

2021

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rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis

Journal of autoimmunity, 2022-01, Vol.126, p.102775-102775, Article 102775

2022

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Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population

Frontiers in immunology, 2023, Vol.14, p.1151502-1151502

2023

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Disease susceptibility genes shared by primary biliary cirrhosis and Crohn's disease in the Japanese population

Journal of human genetics, 2015-09, Vol.60 (9), p.525-531

2015

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Support Vector Machine model for hERG inhibitory activities based on the integrated hERG database using descriptor selection by NSGA-II

Construction of an integrated database for hERG blocking small molecules

The Genetics of Primary Biliary Cholangitis: A GWAS and Post-GWAS Update

Clinical application of exome sequencing in undiagnosed genetic conditions

Analysis of whole Y-chromosome sequences reveals the Japanese population history in the Jomon period

Principal contribution of HLA-DQ alleles, DQB106:04 and DQB103:01, to disease resistance against primary biliary cholangitis in a Japanese population

rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis

FMODB: The World’s First Database of Quantum Mechanical Calculations for Biomacromolecules Based on the Fragment Molecular Orbital Method

Inhibitory effects of biseokeaniamide A against lipopolysaccharide-induced signal transduction

Identification of HLA-A02:06:01 as the primary disease susceptibility HLA allele in cold medicine-related Stevens-Johnson syndrome with severe ocular complications by high-resolution NGS-based HLA typing

rs10924104 in the expression enhancer motif of CD58 confers susceptibility to human autoimmune diseases

Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer

Mutation in TECPR2 Reveals a Role for Autophagy in Hereditary Spastic Paraparesis

Significance of functional disease-causal/susceptible variants identified by whole-genome analyses for the understanding of human diseases

The ubiquinone synthesis pathway is a promising drug target for Chagas disease

Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis

Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population

Prediction of sites of metabolism in a substrate molecule, instanced by carbamazepine oxidation by CYP3A4

Statistical analysis of interactions among amino acid residues in apo structures using fragment molecular orbital method

A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides

Quantitative prediction of hERG inhibitory activities using support vector regression and the integrated hERG dataset in AMED cardiotoxicity database

rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis

Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population

Disease susceptibility genes shared by primary biliary cirrhosis and Crohn's disease in the Japanese population

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