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A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

eLife, 2018-11, Vol.7

2018

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Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment

Cell reports (Cambridge), 2021-01, Vol.34 (2), p.108622-108622, Article 108622

2021

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Developmental gene networks: a triathlon on the course to T cell identity

Nature reviews. Immunology, 2014-08, Vol.14 (8), p.529-545

2014

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gene regulatory network armature for T lymphocyte specification

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20100-20105

2008

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Launching the T-cell-lineage developmental programme

Nature reviews. Immunology, 2008-01, Vol.8 (1), p.9-21

2008

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Notch/Delta Signaling Constrains Reengineering of Pro-T Cells by PU.1

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (32), p.11993-11998

2006

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Fine-scale staging of T cell lineage commitment in adult mouse thymus

The Journal of immunology (1950), 2010-07, Vol.185 (1), p.284-293

2010

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Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

Nature immunology, 2018-12, Vol.19 (12), p.1427-1440

2018

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Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment

Nature immunology, 2016-08, Vol.17 (8), p.956-965

2016

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Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

Nature Immunology, 2007-08, Vol.8 (8), p.845-855

2007

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Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development

Cell systems, 2019-10, Vol.9 (4), p.321-337.e9

2019

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Deficiency of Nuclear Factor-κB c-Rel Accelerates the Development of Autoimmune Diabetes in NOD Mice

Diabetes (New York, N.Y.), 2016-08, Vol.65 (8), p.2367-2379

2016

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Hematopoiesis and T-cell specification as a model developmental system

Immunological reviews, 2016-05, Vol.271 (1), p.72-97

2016

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Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

Leukemia, 2020-05, Vol.34 (5), p.1241-1252

2020

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Transcription factor expression dynamics of early T-lymphocyte specification and commitment

Developmental biology, 2009-01, Vol.325 (2), p.444-467

2009

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Lineage Divergence at the First TCR-Dependent Checkpoint: Preferential gamma delta and Impaired alpha beta T Cell Development in Nonobese Diabetic Mice

The Journal of immunology (1950), 2011-01, Vol.186 (2), p.826-837

2011

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Lineage divergence at the first TCR-dependent checkpoint: preferential γδ and impaired αβ T cell development in nonobese diabetic mice

The Journal of immunology (1950), 2011-01, Vol.186 (2), p.826-837

2011

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Loss of T cell progenitor checkpoint control underlies leukemia initiation in Rag1-deficient nonobese diabetic mice

The Journal of immunology (1950), 2013-04, Vol.190 (7), p.3276-3288

2013

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Progression of regulatory gene expression states in fetal and adult pro-T-cell development

Immunological reviews, 2006-02, Vol.209 (1), p.212-236

2006

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Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment

Cold Spring Harbor Symposia on Quantitative Biology, 2013, Vol.78, p.31-41

2013

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Deranged Early T Cell Development in Immunodeficient Strains of Nonobese Diabetic Mice

The Journal of immunology (1950), 2004-11, Vol.173 (9), p.5381-5391

2004

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A New Regulatory Region of the IL-2 Locus That Confers Position-Independent Transgene Expression

The Journal of immunology (1950), 2001-02, Vol.166 (3), p.1730-1739

2001

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Developmental and Molecular Characterization of Emerging β- and γδ-Selected Pre-T Cells in the Adult Mouse Thymus

Immunity (Cambridge, Mass.), 2006, Vol.24 (1), p.53-64

2006

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Developmental and Molecular Characterization of Emerging beta - and gamma delta - Selected Pre-T Cells in the Adult Mouse Thymus

Immunity (Cambridge, Mass.), 2006-01, Vol.24 (1), p.53-64

2006

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MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells

Kidney international, 1990-02, Vol.37 (2), p.783-792

1990

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A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment

Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment

Developmental gene networks: a triathlon on the course to T cell identity

gene regulatory network armature for T lymphocyte specification

Launching the T-cell-lineage developmental programme

Notch/Delta Signaling Constrains Reengineering of Pro-T Cells by PU.1

Fine-scale staging of T cell lineage commitment in adult mouse thymus

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment

Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development

Deficiency of Nuclear Factor-κB c-Rel Accelerates the Development of Autoimmune Diabetes in NOD Mice

Hematopoiesis and T-cell specification as a model developmental system

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

Transcription factor expression dynamics of early T-lymphocyte specification and commitment

Lineage Divergence at the First TCR-Dependent Checkpoint: Preferential gamma delta and Impaired alpha beta T Cell Development in Nonobese Diabetic Mice

Lineage divergence at the first TCR-dependent checkpoint: preferential γδ and impaired αβ T cell development in nonobese diabetic mice

Loss of T cell progenitor checkpoint control underlies leukemia initiation in Rag1-deficient nonobese diabetic mice

Progression of regulatory gene expression states in fetal and adult pro-T-cell development

Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment

Deranged Early T Cell Development in Immunodeficient Strains of Nonobese Diabetic Mice

A New Regulatory Region of the IL-2 Locus That Confers Position-Independent Transgene Expression

Developmental and Molecular Characterization of Emerging β- and γδ-Selected Pre-T Cells in the Adult Mouse Thymus

Developmental and Molecular Characterization of Emerging beta - and gamma delta - Selected Pre-T Cells in the Adult Mouse Thymus

MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells

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