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First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation

Journal of medicinal chemistry, 2022-09, Vol.65 (18), p.12140-12162

2022

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Design, synthesis, and biological activity evaluation of novel HDAC3 selective inhibitors for combination with Venetoclax against acute myeloid leukemia

European journal of medicinal chemistry, 2024-10, Vol.276, p.116663, Article 116663

2024

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Design, synthesis, and biological evaluation of novel HDAC/CD13 dual inhibitors for the treatment of cancer

European journal of medicinal chemistry, 2023-11, Vol.260, p.115752, Article 115752

2023

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Comparison of three zinc binding groups for HDAC inhibitors – A potency, selectivity and enzymatic kinetics study

Bioorganic & medicinal chemistry letters, 2022-08, Vol.70, p.128797-128797, Article 128797

2022

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Potent Hydrazide-Based HDAC Inhibitors with a Superior Pharmacokinetic Profile for Efficient Treatment of Acute Myeloid Leukemia In Vivo

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.285-302

2022

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Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors

European journal of medicinal chemistry, 2023-01, Vol.246, p.115004-115004, Article 115004

2023

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Psammaplin A analogues with modified disulfide bond targeting histone deacetylases: Synthesis and biological evaluation

European journal of medicinal chemistry, 2024-09, Vol.275, p.116541, Article 116541

2024

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Discovery of Novel 2,3-Dihydro‑1H‑indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.16141-16167

2023

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HDAC/NAMPT dual inhibitors overcome initial drug-resistance in p53-null leukemia cells

European journal of medicinal chemistry, 2024-02, Vol.266, p.116127-116127, Article 116127

2024

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Discovery of Novel 2,3-Dihydro-1 H -indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.16141-16167

2023

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Discovery of new non-covalent and covalent inhibitors targeting SARS-CoV-2 papain-like protease and main protease

Bioorganic chemistry, 2023-11, Vol.140, p.106830-106830, Article 106830

2023

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1,2-Isoselenazol-3(2H)-one derivatives as NDM-1 inhibitors displaying synergistic antimicrobial effects with meropenem on NDM-1 producing clinical isolates

Bioorganic chemistry, 2022-12, Vol.129, p.106153-106153, Article 106153

2022

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Design, synthesis and biological evaluation of hybrid of ubenimex-fluorouracil for hepatocellular carcinoma therapy

Bioorganic chemistry, 2021-11, Vol.116, p.105343-105343, Article 105343

2021

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Experimental investigation on the vortex-induced vibration response of a lazy-wave flexible riser filled with different fluid media

Physics of fluids (1994), 2024-03, Vol.36 (3)

2024

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Communication Topology Optimization for Time-Delay Cyber-Physical Microgrids Under Distributed Control

IEEE transactions on smart grid, 2024-09, Vol.15 (5), p.5087-5101

2024

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Prescribed performance adaptive event-triggered consensus control for multiagent systems with input saturation

Frontiers in neurorobotics, 2023-01, Vol.16, p.1103462-1103462

2023

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Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner

Cell reports (Cambridge), 2023-10, Vol.42 (10), p.113157-113157, Article 113157

2023

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ZIP Genes Are Involved in the Retransfer of Zinc Ions during the Senescence of Zinc-Deficient Rice Leaves

International journal of molecular sciences, 2023-09, Vol.24 (18), p.13989

2023

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Nonlinear Effects of Eco-Industrial Parks on Sulfur Dioxide and Carbon Dioxide Emissions—Estimation Based on Nonlinear DID

Sustainability, 2023-01, Vol.15 (3), p.1988

2023

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Label-free in vivo assessment of brain mitochondrial redox states during the development of diabetic cognitive impairment using Raman spectroscopy

Free radical biology & medicine, 2022-05, Vol.184, p.1-11

2022

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Fabrication of double core-shell Si-based anode materials with nanostructure for lithium-ion battery

RSC advances, 2018-01, Vol.8 (17), p.9094-9102

2018

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Engineering of Ni3S4/Co3S4 nanosheets@N, S co-doped carbon anode for lithium-ion batteries

Ionics, 2021-12, Vol.27 (12), p.5089-5096

2021

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Development of de-novo coronavirus 3-chymotrypsin-like protease (3CL pro ) inhibitors since COVID-19 outbreak: A strategy to tackle challenges of persistent virus infection

European journal of medicinal chemistry, 2024-01, Vol.264, p.115979-115979, Article 115979

2024

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Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy

Heliyon, 2024-04, Vol.10 (7), p.e28768-e28768, Article e28768

2024

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Improved design and optimization of synthetic n-Butyl acetate process to save energy

Separation science and technology, 2022-04, Vol.57 (6), p.1000-1011

2022

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First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation

Design, synthesis, and biological activity evaluation of novel HDAC3 selective inhibitors for combination with Venetoclax against acute myeloid leukemia

Design, synthesis, and biological evaluation of novel HDAC/CD13 dual inhibitors for the treatment of cancer

Comparison of three zinc binding groups for HDAC inhibitors – A potency, selectivity and enzymatic kinetics study

Potent Hydrazide-Based HDAC Inhibitors with a Superior Pharmacokinetic Profile for Efficient Treatment of Acute Myeloid Leukemia In Vivo

Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors

Psammaplin A analogues with modified disulfide bond targeting histone deacetylases: Synthesis and biological evaluation

Discovery of Novel 2,3-Dihydro‑1H‑indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis

HDAC/NAMPT dual inhibitors overcome initial drug-resistance in p53-null leukemia cells

Discovery of Novel 2,3-Dihydro-1 H -indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis

Discovery of new non-covalent and covalent inhibitors targeting SARS-CoV-2 papain-like protease and main protease

1,2-Isoselenazol-3(2H)-one derivatives as NDM-1 inhibitors displaying synergistic antimicrobial effects with meropenem on NDM-1 producing clinical isolates

Design, synthesis and biological evaluation of hybrid of ubenimex-fluorouracil for hepatocellular carcinoma therapy

Experimental investigation on the vortex-induced vibration response of a lazy-wave flexible riser filled with different fluid media

Communication Topology Optimization for Time-Delay Cyber-Physical Microgrids Under Distributed Control

Prescribed performance adaptive event-triggered consensus control for multiagent systems with input saturation

Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner

ZIP Genes Are Involved in the Retransfer of Zinc Ions during the Senescence of Zinc-Deficient Rice Leaves

Nonlinear Effects of Eco-Industrial Parks on Sulfur Dioxide and Carbon Dioxide Emissions—Estimation Based on Nonlinear DID

Label-free in vivo assessment of brain mitochondrial redox states during the development of diabetic cognitive impairment using Raman spectroscopy

Fabrication of double core-shell Si-based anode materials with nanostructure for lithium-ion battery

Engineering of Ni3S4/Co3S4 nanosheets@N, S co-doped carbon anode for lithium-ion batteries

Development of de-novo coronavirus 3-chymotrypsin-like protease (3CL pro ) inhibitors since COVID-19 outbreak: A strategy to tackle challenges of persistent virus infection

Cardiac magnetic resonance feature tracking derived left atrial strain in the diagnosis of patients with constrictive pericarditis and restrictive cardiomyopathy

Improved design and optimization of synthetic n-Butyl acetate process to save energy

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