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Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells

Cell stem cell, 2015-04, Vol.16 (4), p.373-385

2015

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Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

Nature (London), 2012-02, Vol.482 (7384), p.216-220

2012

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Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells

PloS one, 2011-03, Vol.6 (3), p.e17540-e17540

2011

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The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells

Cell reports (Cambridge), 2013-11, Vol.5 (4), p.974-985

2013

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The Role of PERK in Understanding Development of Neurodegenerative Diseases

International journal of molecular sciences, 2021-08, Vol.22 (15), p.8146

2021

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A high efficiency precision genome editing method with CRISPR in iPSCs

Scientific reports, 2024-04, Vol.14 (1), p.9933-9933, Article 9933

2024

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Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

Neurobiology of disease, 2017-10, Vol.106, p.222-234

2017

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Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo

Journal of Alzheimer's disease, 2019-01, Vol.67 (2), p.541-553

2019

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Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1

Human molecular genetics, 2012-06, Vol.21 (12), p.2651-2662

2012

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TOX3 regulates calcium-dependent transcription in neurons

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2909-2914

2009

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A narrative review of music therapy for neuropsychiatric symptoms in Alzheimer's disease and rationale for protocolized music teletherapy

Frontiers in medicine, 2023, Vol.10, p.1248245-1248245

2023

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Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons

ACS omega, 2021-05, Vol.6 (20), p.13033-13056

2021

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Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients

Cell stem cell, 2021-09, Vol.28 (9), p.1533-1548.e6

2021

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Extracellular Vesicles Isolated from Familial Alzheimer’s Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain

Journal of Alzheimer's disease, 2019-01, Vol.72 (2), p.575-585

2019

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Alzheimer’s Dementia due to Suspected CTE from Subconcussive Head Impact

Case reports in neurological medicine, 2018-01, Vol.2018 (2018), p.1-4

2018

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Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo

Journal of Alzheimer's disease, 2019, Vol.67 (2), p.541

2019

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Emotional Lability as a Unique Presenting Sign of Suspected Chronic Traumatic Encephalopathy

Case reports in neurological medicine, 2018-01, Vol.2018 (2018), p.1-4

2018

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Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress

Human molecular genetics, 2018-11, Vol.27 (22), p.3951-3963

2018

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A Case of Frontotemporal Lobar Degeneration With FUS-Positive Pathology (FTLD-FET) With Corticobasal Features and Language Deficits

Journal of neuropathology and experimental neurology, 2021-09, Vol.80 (9), p.890-892

2021

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Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds

Tissue engineering. Part A, 2011-11, Vol.17 (21-22), p.2583-2592

2011

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Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers

JAMA neurology, 2014-12, Vol.71 (12), p.1481

2014

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Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome: A Phase 1b Randomized Clinical Trial

JAMA neurology, 2022-06, Vol.79 (6), p.565

2022

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Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease

Alzheimer's & dementia, 2022-11, Vol.18 (11), p.2117-2130

2022

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TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex

Journal of cell science, 2011-01, Vol.124 (2), p.252-260

2011

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Dedifferentiation and neuronal repression define familial Alzheimer's disease

Science advances, 2020-11, Vol.6 (46)

2020

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Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells

The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells

The Role of PERK in Understanding Development of Neurodegenerative Diseases

A high efficiency precision genome editing method with CRISPR in iPSCs

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo

Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1

TOX3 regulates calcium-dependent transcription in neurons

A narrative review of music therapy for neuropsychiatric symptoms in Alzheimer's disease and rationale for protocolized music teletherapy

Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons

Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients

Extracellular Vesicles Isolated from Familial Alzheimer’s Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain

Alzheimer’s Dementia due to Suspected CTE from Subconcussive Head Impact

Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo

Emotional Lability as a Unique Presenting Sign of Suspected Chronic Traumatic Encephalopathy

Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress

A Case of Frontotemporal Lobar Degeneration With FUS-Positive Pathology (FTLD-FET) With Corticobasal Features and Language Deficits

Decellularized porcine brain matrix for cell culture and tissue engineering scaffolds

Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers

Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome: A Phase 1b Randomized Clinical Trial

Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease

TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex

Dedifferentiation and neuronal repression define familial Alzheimer's disease

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