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Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

Chemical science (Cambridge), 2020-09, Vol.11 (36), p.994-999

2020

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Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B

Nucleic acids research, 2020-04, Vol.48 (7), p.3949

2020

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Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

Science (American Association for the Advancement of Science), 2016-07, Vol.353 (6297), p.394-399

2016

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RNA recognition motifs of disease-linked RNA-binding proteins contribute to amyloid formation

Scientific reports, 2019-04, Vol.9 (1), p.6171-6171, Article 6171

2019

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Using an Old Drug to Target a New Drug Site: Application of Disulfiram to Target the Zn-Site in HCV NS5A Protein

Journal of the American Chemical Society, 2016-03, Vol.138 (11), p.3856-3862

2016

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Mechanistic Insights into Harmine-Mediated Inhibition of Human DNA Methyltransferases and Prostate Cancer Cell Growth

ACS chemical biology, 2023-06, Vol.18 (6), p.1335-1350

2023

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The Truncated C-terminal RNA Recognition Motif of TDP-43 Protein Plays a Key Role in Forming Proteinaceous Aggregates

The Journal of biological chemistry, 2013-03, Vol.288 (13), p.9049-9057

2013

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Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G

Cell reports (Cambridge), 2016-07, Vol.16 (2), p.279-287

2016

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Stabilization and Enhancement of the Antiapoptotic Activity of Mcl-1 by TCTP

Molecular and Cellular Biology, 2005-04, Vol.25 (8), p.3117-3126

2005

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Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways

PLoS biology, 2014-03, Vol.12 (3), p.e1001803-e1001803

2014

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Crystal structure of Escherichia coli PNPase: central channel residues are involved in processive RNA degradation

RNA (Cambridge), 2008-11, Vol.14 (11), p.2361-2371

2008

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The Conserved Asparagine in the HNH Motif Serves an Important Structural Role in Metal Finger Endonucleases

Journal of molecular biology, 2007-05, Vol.368 (3), p.812-821

2007

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Lipid-Binding Regions within PKC-Related Serine/Threonine Protein Kinase N1 (PKN1) Required for Its Regulation

Biochemistry (Easton), 2024-03, Vol.63 (6), p.743-753

2024

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Crystal Structure of CRN-4: Implications for Domain Function in Apoptotic DNA Degradation

Molecular and Cellular Biology, 2009-01, Vol.29 (2), p.448-457

2009

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Structures, Mechanisms, and Functions of His-Me Finger Nucleases

Trends in biochemical sciences (Amsterdam. Regular ed.), 2020-11, Vol.45 (11), p.935-946

2020

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The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids

Nucleic acids research, 2014-04, Vol.42 (7), p.4712

2014

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Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

Nature communications, 2014-09, Vol.5 (1), p.4824, Article 4824

2014

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Frontotemporal dementia‐linked P112H mutation of TDP‐43 induces protein structural change and impairs its RNA binding function

Protein science, 2021-02, Vol.30 (2), p.350-365

2021

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Identification of an Essential Cleavage Site in ColE7 Required for Import and Killing of Cells

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.24663-24668

2005

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Structural insights into nanoRNA degradation by human Rexo2

RNA (Cambridge), 2019-06, Vol.25 (6), p.737-746

2019

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Dimeric assembly of human Suv3 helicase promotes its RNA unwinding function in mitochondrial RNA degradosome for RNA decay

Protein science, 2022-05, Vol.31 (5), p.e4312-n/a

2022

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Tudor staphylococcal nuclease is a structure-specific ribonuclease that degrades RNA at unstructured regions during microRNA decay

RNA (Cambridge), 2018-05, Vol.24 (5), p.739-748

2018

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Structural insights into TDP-43 in nucleic-acid binding and domain interactions

Nucleic acids research, 2009-04, Vol.37 (6), p.1799

2009

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Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography

Journal of molecular biology, 2001-04, Vol.308 (2), p.263-278

2001

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A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication

Nucleic acids research, 2019-06, Vol.47 (10), p.5405

2019

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Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B

Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

RNA recognition motifs of disease-linked RNA-binding proteins contribute to amyloid formation

Using an Old Drug to Target a New Drug Site: Application of Disulfiram to Target the Zn-Site in HCV NS5A Protein

Mechanistic Insights into Harmine-Mediated Inhibition of Human DNA Methyltransferases and Prostate Cancer Cell Growth

The Truncated C-terminal RNA Recognition Motif of TDP-43 Protein Plays a Key Role in Forming Proteinaceous Aggregates

Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G

Stabilization and Enhancement of the Antiapoptotic Activity of Mcl-1 by TCTP

Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways

Crystal structure of Escherichia coli PNPase: central channel residues are involved in processive RNA degradation

The Conserved Asparagine in the HNH Motif Serves an Important Structural Role in Metal Finger Endonucleases

Lipid-Binding Regions within PKC-Related Serine/Threonine Protein Kinase N1 (PKN1) Required for Its Regulation

Crystal Structure of CRN-4: Implications for Domain Function in Apoptotic DNA Degradation

Structures, Mechanisms, and Functions of His-Me Finger Nucleases

The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids

Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

Frontotemporal dementia‐linked P112H mutation of TDP‐43 induces protein structural change and impairs its RNA binding function

Identification of an Essential Cleavage Site in ColE7 Required for Import and Killing of Cells

Structural insights into nanoRNA degradation by human Rexo2

Dimeric assembly of human Suv3 helicase promotes its RNA unwinding function in mitochondrial RNA degradosome for RNA decay

Tudor staphylococcal nuclease is a structure-specific ribonuclease that degrades RNA at unstructured regions during microRNA decay

Structural insights into TDP-43 in nucleic-acid binding and domain interactions

Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography

A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication

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