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Targeting ferroptosis alleviates methionine‐choline deficient (MCD)‐diet induced NASH by suppressing liver lipotoxicity

Liver international, 2020-06, Vol.40 (6), p.1378-1394

2020

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Autophagy regulation by nutrient signaling

Cell research, 2014-01, Vol.24 (1), p.42-57

2014

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Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis

Nature communications, 2018-02, Vol.9 (1), p.508-17, Article 508

2018

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Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy

Autophagy, 2013-12, Vol.9 (12), p.1983-1995

2013

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Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma

Oncogene, 2018-03, Vol.37 (12), p.1637-1653

2018

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Structural insights into TSC complex assembly and GAP activity on Rheb

Nature communications, 2021-01, Vol.12 (1), p.339-339, Article 339

2021

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Endothelin Promotes Colorectal Tumorigenesis by Activating YAP/TAZ

Cancer research (Chicago, Ill.), 2017-05, Vol.77 (9), p.2413-2423

2017

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Osmotic stress‐induced phosphorylation by NLK at Ser128 activates YAP

EMBO reports, 2017-01, Vol.18 (1), p.72-86

2017

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The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis

Cell death & disease, 2019-10, Vol.10 (10), p.755-12, Article 755

2019

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GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

eLife, 2019-05, Vol.8

2019

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Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration

The Journal of biological chemistry, 2016-09, Vol.291 (36), p.18947-18958

2016

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The SIN1-PH Domain Connects mTORC2 to PI3K

Cancer discovery, 2015-11, Vol.5 (11), p.1127-1129

2015

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Structural insights of mTOR complex 1

Cell research, 2016-03, Vol.26 (3), p.267-268

2016

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SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes

The FEBS journal, 2017-11, Vol.284 (21), p.3619-3636

2017

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Nutrient Sensing, Metabolism, and Cell Growth Control

Molecular cell, 2013-02, Vol.49 (3), p.379-387

2013

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Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK

Cell death & disease, 2021-10, Vol.12 (11), p.972-972, Article 972

2021

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Elevated nuclear localization of glycolytic enzyme TPI1 promotes lung adenocarcinoma and enhances chemoresistance

Cell death & disease, 2022-03, Vol.13 (3), p.205-205, Article 205

2022

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NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition

Genes & development, 2015-11, Vol.29 (22), p.2362-2376

2015

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Integration analysis identifies the role of metallothionein in the progression from hepatic steatosis to steatohepatitis

Frontiers in endocrinology (Lausanne), 2022-10, Vol.13, p.951093-951093

2022

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CBFB-MYH11 Fusion Sequesters RUNX1 in Cytoplasm to Prevent DNMT3A Recruitment to Target Genes in AML

Frontiers in cell and developmental biology, 2021-07, Vol.9, p.675424-675424

2021

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ALK fusion promotes metabolic reprogramming of cancer cells by transcriptionally upregulating PFKFB3

Oncogene, 2022-09, Vol.41 (40), p.4547-4559

2022

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TET2 deficiency sensitizes tumor cells to statins by reducing HMGCS1 expression

Oncogene, 2022-12, Vol.41 (50), p.5385-5396

2022

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A Class of Disulfide Compounds Suppresses Ferroptosis by Stabilizing GPX4

ACS chemical biology, 2022-12, Vol.17 (12), p.3389-3406

2022

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ELP3 Acetyltransferase is phosphorylated and regulated by the oncogenic anaplastic lymphoma kinase (ALK)

Biochemical journal, 2019-08, Vol.476 (15), p.2239-2254

2019

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RNase9, an Androgen-Dependent Member of the RNase A Family, Is Specifically Expressed in the Rat Epididymis

Biology of reproduction, 2007, Vol.76 (1), p.63-73

2007

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Targeting ferroptosis alleviates methionine‐choline deficient (MCD)‐diet induced NASH by suppressing liver lipotoxicity

Autophagy regulation by nutrient signaling

Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis

Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy

Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma

Structural insights into TSC complex assembly and GAP activity on Rheb

Endothelin Promotes Colorectal Tumorigenesis by Activating YAP/TAZ

Osmotic stress‐induced phosphorylation by NLK at Ser128 activates YAP

The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration

The SIN1-PH Domain Connects mTORC2 to PI3K

Structural insights of mTOR complex 1

SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes

Nutrient Sensing, Metabolism, and Cell Growth Control

Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK

Elevated nuclear localization of glycolytic enzyme TPI1 promotes lung adenocarcinoma and enhances chemoresistance

NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition

Integration analysis identifies the role of metallothionein in the progression from hepatic steatosis to steatohepatitis

CBFB-MYH11 Fusion Sequesters RUNX1 in Cytoplasm to Prevent DNMT3A Recruitment to Target Genes in AML

ALK fusion promotes metabolic reprogramming of cancer cells by transcriptionally upregulating PFKFB3

TET2 deficiency sensitizes tumor cells to statins by reducing HMGCS1 expression

A Class of Disulfide Compounds Suppresses Ferroptosis by Stabilizing GPX4

ELP3 Acetyltransferase is phosphorylated and regulated by the oncogenic anaplastic lymphoma kinase (ALK)

RNase9, an Androgen-Dependent Member of the RNase A Family, Is Specifically Expressed in the Rat Epididymis

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