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Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy

Molecules (Basel, Switzerland), 2019-01, Vol.24 (3), p.429

2019

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Therapeutic gene regulation using pyrrole–imidazole polyamides

Advanced drug delivery reviews, 2019-07, Vol.147, p.66-85

2019

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Mitochondria and G-quadruplex evolution: an intertwined relationship

Trends in genetics, 2023-01, Vol.39 (1), p.15-30

2023

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Inhibition of GLI-Mediated Transcription by Cyclic Pyrrole-Imidazole Polyamide in Cancer Stem Cells

Bulletin of the Chemical Society of Japan, 2022-04, Vol.95 (4), p.693-699

2022

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Direct Observation of H3–H4 Octasome by High‐Speed AFM

Chemistry : a European journal, 2018-10, Vol.24 (60), p.15998-16002

2018

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Soluble Guanylate Cyclase Stimulators and Activators: Where are We and Where to Go?

Mini reviews in medicinal chemistry, 2019-01, Vol.19 (18), p.1544-1557

2019

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The RAF-MEK-ERK pathway: targeting ERK to overcome obstacles to effective cancer therapy

Future medicinal chemistry, 2015-03, Vol.7 (3), p.269-289

2015

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Direct Observation of the Double‐Stranded DNA Formation through Metal Ion‐Mediated Base Pairing in the Nanoscale Structure

Chemistry : a European journal, 2019-01, Vol.25 (6), p.1446-1450

2019

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A synthetic transcription factor pair mimic for precise recruitment of an epigenetic modifier to the targeted DNA locus

Chemical communications (Cambridge, England), 2020-02, Vol.56 (15), p.2296-2299

2020

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A Novel PDK1/MEK Dual Inhibitor Induces Cytoprotective Autophagy via the PDK1/Akt Signaling Pathway in Non-Small Cell Lung Cancer

Pharmaceuticals (Basel, Switzerland), 2023-02, Vol.16 (2), p.244

2023

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A novel dual MEK/PDK1 inhibitor 9za retards the cell cycle at G0/G1 phase and induces mitochondrial apoptosis in non-small cell lung cancer cells

PeerJ (San Francisco, CA), 2020-10, Vol.8, p.e9981-e9981

2020

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Synthetic DNA-Binding Inhibitor of HES1 Alters the Notch Signaling Pathway and Induces Neuronal Differentiation

ACS omega, 2018-03, Vol.3 (3), p.3608-3616

2018

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Mitochondria and G-quadruplex evolution: an intertwined relationship

Trends in genetics, 2023-01, Vol.39 (1), p.15-30

2023

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Current advances in idiopathic pulmonary fibrosis: the pathogenesis, therapeutic strategies and candidate molecules

Future medicinal chemistry, 2019-10, Vol.11 (19), p.2595-2620

2019

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Chem-map profiles drug binding to chromatin in cells

Nature biotechnology, 2023-09, Vol.41 (9), p.1265-1271

2023

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Artificial Assemblies with Cooperative DNA Recognition

YU, Zutao

1st edition, 2020

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Pip-HoGu: An Artificial Assembly with Cooperative DNA Recognition Capable of Mimicking Transcription Factor Pairs

Journal of the American Chemical Society, 2018-02, Vol.140 (7), p.2426-2429

2018

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G-quadruplex DNA structure is a positive regulator of MYC transcription

Proceedings of the National Academy of Sciences - PNAS, 2024-02, Vol.121 (7), p.e2320240121-e2320240121

2024

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Binding pocket-based design, synthesis and biological evaluation of novel selective BRD4-BD1 inhibitors

Bioorganic & medicinal chemistry, 2019-05, Vol.27 (9), p.1871-1881

2019

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Chemical Probe-Based Nanopore Sequencing to Selectively Assess the RNA Modifications

ACS chemical biology, 2022-10, Vol.17 (10), p.2704-2709

2022

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Dual inhibitors of RAF-MEK-ERK and PI3K-PDK1-AKT pathways: Design, synthesis and preliminary anticancer activity studies of 3-substituted-5-(phenylamino) indolone derivatives

Bioorganic & medicinal chemistry, 2019-03, Vol.27 (6), p.944-954

2019

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Effective treatment of vancomycin nephrotoxicity with continuous venous‐venous haemodiafiltration (CVVHDF) in a paediatric patient

Journal of clinical pharmacy and therapeutics, 2020-08, Vol.45 (4), p.852-855

2020

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Orthogonal γPNA Dimerization Domains Empower DNA Binders with Cooperativity and Versatility Mimicking that of Transcription Factor Pairs

Chemistry : a European journal, 2018-09, Vol.24 (53), p.14183-14188

2018

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UVA irradiation of BrU-substituted DNA in the presence of Hoechst 33258

Bioorganic & medicinal chemistry, 2018-01, Vol.26 (1), p.37-40

2018

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Antiproliferative and apoptotic activities of sequence-specific histone acetyltransferase inhibitors

European journal of medicinal chemistry, 2017-09, Vol.138, p.320-327

2017

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Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy

Therapeutic gene regulation using pyrrole–imidazole polyamides

Mitochondria and G-quadruplex evolution: an intertwined relationship

Inhibition of GLI-Mediated Transcription by Cyclic Pyrrole-Imidazole Polyamide in Cancer Stem Cells

Direct Observation of H3–H4 Octasome by High‐Speed AFM

Soluble Guanylate Cyclase Stimulators and Activators: Where are We and Where to Go?

The RAF-MEK-ERK pathway: targeting ERK to overcome obstacles to effective cancer therapy

Direct Observation of the Double‐Stranded DNA Formation through Metal Ion‐Mediated Base Pairing in the Nanoscale Structure

A synthetic transcription factor pair mimic for precise recruitment of an epigenetic modifier to the targeted DNA locus

A Novel PDK1/MEK Dual Inhibitor Induces Cytoprotective Autophagy via the PDK1/Akt Signaling Pathway in Non-Small Cell Lung Cancer

A novel dual MEK/PDK1 inhibitor 9za retards the cell cycle at G0/G1 phase and induces mitochondrial apoptosis in non-small cell lung cancer cells

Synthetic DNA-Binding Inhibitor of HES1 Alters the Notch Signaling Pathway and Induces Neuronal Differentiation

Mitochondria and G-quadruplex evolution: an intertwined relationship

Current advances in idiopathic pulmonary fibrosis: the pathogenesis, therapeutic strategies and candidate molecules

Chem-map profiles drug binding to chromatin in cells

Artificial Assemblies with Cooperative DNA Recognition

Pip-HoGu: An Artificial Assembly with Cooperative DNA Recognition Capable of Mimicking Transcription Factor Pairs

G-quadruplex DNA structure is a positive regulator of MYC transcription

Binding pocket-based design, synthesis and biological evaluation of novel selective BRD4-BD1 inhibitors

Chemical Probe-Based Nanopore Sequencing to Selectively Assess the RNA Modifications

Dual inhibitors of RAF-MEK-ERK and PI3K-PDK1-AKT pathways: Design, synthesis and preliminary anticancer activity studies of 3-substituted-5-(phenylamino) indolone derivatives

Effective treatment of vancomycin nephrotoxicity with continuous venous‐venous haemodiafiltration (CVVHDF) in a paediatric patient

Orthogonal γPNA Dimerization Domains Empower DNA Binders with Cooperativity and Versatility Mimicking that of Transcription Factor Pairs

UVA irradiation of BrU-substituted DNA in the presence of Hoechst 33258

Antiproliferative and apoptotic activities of sequence-specific histone acetyltransferase inhibitors

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